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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 26-AUG-2017
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPN034156
 - locus tag: SPN034156_18520 [new locus tag: SPN034156_RS10270 ]
 - pan locus tag?: PNEUPAN001864000
 - symbol: pfk
 - pan gene symbol?: pfkA
 - synonym:
 - product: 6-phosphofructokinase
 
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
 - locus tag: SPN034156_18520 [new locus tag: SPN034156_RS10270 ]
 - symbol: pfk
 - product: 6-phosphofructokinase
 - replicon: chromosome
 - strand: +
 - coordinates: 1922366..1923373
 - length: 1008
 - essential: unknown other strains
 
⊟Accession numbers[edit | edit source]
- Location: FQ312045 (1922366..1923373) NCBI
 - BioCyc:
 - MicrobesOnline:
 - PneumoBrowse for strain D39V: SPV_0789 PneumoBrowse
 
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGAAACGTATTGCTGTTTTGACTAGTGGCGGAGACGCACCTGGTATGAACGCTGCTATC
CGTGCAGTTGTTCGTCAAGCAATTTCAGAAGGAATGGAAGTGTTTGGTATCTATGACGGA
TATGCTGGTATGGTTGCCGGTGAAATTCATCCCCTAGATGCAGCTTCAGTAGGAGACATC
ATTTCTCGTGGTGGTACTTTTCTTCACTCAGCTCGTTACCCAGAGTTCGCTCAACTTGAA
GGGCAACTTAAAGGGATTGAGCAATTGAAAAAACACGGAATTGAAGGTGTAGTTGTTATC
GGTGGTGACGGATCTTACCACGGCGCTATGCGTTTGACTGAACATGGCTTCCCAGCTATT
GGTCTTCCAGGTACAATCGATAACGATATCGTTGGTACTGACTTTACAATCGGTTTTGAC
ACAGCGGTTACTACTGCCATGGACGCTATCGATAAGATTCGTGATACATCATCAAGTCAC
CGTCGTACTTTTGTAATCGAAGTTATGGGACGTAACGCTGGTGATATCGCTCTTTGGGCT
GGTATTGCAACTGGTGCTGATGAAATCATCATCCCTGAAGCAGGCTGCAAGATGGAAGAT
ATCGTAGCAAGCATCAAAGCTGGTTATGAATGTGGTAAAAAACACAATATCATCGTCTTA
GCTGAAGGTGTGATGTCAGCGGCTGAATTTGGTCAAAAACTTAAAGAAGCTGGAGATACA
AGCGACCTTCGTGTAACAGAACTTGGACATATTCAACGTGGTGGTTCTCCAACTGCGCGT
GACCGTGTTTTGGCGTCACGTATGGGTGCACATGCTGTTAAACTTCTTAAAGAAGGTATC
GGTGGTGTTGCGGTTGGTATTCGTAACGAAAAAATGGTTGAAAATCCAATTCTTGGTACT
GCAGAAGAAGGGGCATTGTTTAGCCTTACTGCAGAAGGTAAGATTGTGGTTAACAACCCA
CACAAAGCCGATATTGAGCTATCTAGCTTGAATAAGAGCTTGTCATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN034156_18520 [new locus tag: SPN034156_RS10270 ]
 - symbol: Pfk
 - description: 6-phosphofructokinase
 - length: 335
 - theoretical pI: 5.59903
 - theoretical MW: 35129.9
 - GRAVY: 0.0229851
 
⊟Function[edit | edit source]
- TIGRFAM: Energy metabolism Glycolysis/gluconeogenesis 6-phosphofructokinase (TIGR02482; EC 2.7.1.11; HMM-score: 414.1)and 3 moreEnergy metabolism Glycolysis/gluconeogenesis phosphofructokinase (TIGR02483; HMM-score: 306.4)6-phosphofructokinase (TIGR02478; EC 2.7.1.11; HMM-score: 273.5)Energy metabolism Glycolysis/gluconeogenesis diphosphate--fructose-6-phosphate 1-phosphotransferase (TIGR02477; EC 2.7.1.90; HMM-score: 74.7)
 - TheSEED  : 
- 6-phosphofructokinase (EC 2.7.1.11)
 
Carbohydrates Aminosugars N-Acetyl-Galactosamine and Galactosamine Utilization 6-phosphofructokinase (EC 2.7.1.11)and 1 more - PFAM: PFK (CL0240) PFK; Phosphofructokinase (PF00365; HMM-score: 352.1)and 2 moreNAD_kinase; ATP-NAD kinase N-terminal domain (PF01513; HMM-score: 16.4)Periplas_BP (CL0144) Peripla_BP_1; Periplasmic binding proteins and sugar binding domain of LacI family (PF00532; HMM-score: 12.5)
 
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
 - modifications:
 - cofactors:
 - effectors:
 
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
 - Cytoplasmic Membrane Score: 0
 - Cellwall Score: 0.01
 - Extracellular Score: 0.02
 - Internal Helices: 0
 
 - DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9772
 - Cytoplasmic Membrane Score: 0.0033
 - Cell wall & surface Score: 0.0001
 - Extracellular Score: 0.0194
 
 - SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.020315
 - TAT(Tat/SPI): 0.000856
 - LIPO(Sec/SPII): 0.001981
 
 - predicted transmembrane helices (TMHMM): 0
 
⊟Accession numbers[edit | edit source]
- GI:
 - RefSeq: CCP37521 NCBI
 - UniProt:
 
⊟Protein sequence[edit | edit source]
- MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGMVAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSHRRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGCKMEDIVASIKAGYECGKKHNIIVLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLLKEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSLS
 
⊟Experimental data[edit | edit source]
- protein localization:
 - interaction partners:
 
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
 
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0789 PneumoExpress
 
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]