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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 06-FEB-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F11730 [new locus tag: SPN23F_RS05945 ]
- pan locus tag?: PNEUPAN002532000
- symbol: nth
- pan gene symbol?: nth
- synonym:
- product: putative endonuclease III
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F11730 [new locus tag: SPN23F_RS05945 ]
- symbol: nth
- product: putative endonuclease III
- replicon: chromosome
- strand: -
- coordinates: 1149846..1150451
- length: 606
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: FM211187 (1149846..1150451) NCBI
- BioCyc: see SPN23F_RS05945
- MicrobesOnline: 5831020 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1135 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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121
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541
601ATGGTCTTGTCAAAAAAACGAGCACGAAAGGTGCTAGAAGAAATCATTGCCCTCTTCCCA
GATGCCAAGCCTAGTCTTGATTTTACCAATCATTTTGAACTCCTGGTTGCGGTCATGTTA
TCAGCCCAGACGACAGATGCAGCGGTAAATAAGGCCACACCAGGTCTCTTTGTTGCCTTT
CCAACACCCCAAGCTATGTCTGTAGCGACAGAGAGTGAGATTGCTTCACATATTTCTCGC
TTGGGATTGTATCGGAATAAAGCTAAATTCCTTAAAAAATGTGCCCAACAGTTACTAGAC
GATTTTGATGGTCAAGTCCCTCAGACACGTGAAGAATTGGAGAGTTTGGCAGGTGTTGGT
CGCAAGACAGCCAATGTTGTCATGAGTGTAGGATTTGGGATTCCAGCCTTTGCAGTGGAT
ACTCATGTGGAGCGTATTTGCAAACACCACGATATTGTCAAAAAATCAGCGACGCCACTT
GAGGTGGAAAAGCGGGTCATGGATATCTTGCCGCCTGAGCAGTGGTTAGCTGCCCATCAG
GCCATGATTTATTTTGGAAGAGCCATTTGCCATCCAAAAAATCCAGAGTGTGACCAGTAC
CCATAA60
120
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606
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F11730 [new locus tag: SPN23F_RS05945 ]
- symbol: Nth
- description: putative endonuclease III
- length: 201
- theoretical pI: 8.00285
- theoretical MW: 22295.8
- GRAVY: -0.0950249
⊟Function[edit | edit source]
- reaction: EC 4.2.99.18? ExPASyDNA-(apurinic or apyrimidinic site) lyase The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
- TIGRFAM: DNA metabolism DNA replication, recombination, and repair endonuclease III (TIGR01083; EC 4.2.99.18; HMM-score: 234.6)and 2 moreDNA metabolism DNA replication, recombination, and repair A/G-specific adenine glycosylase (TIGR01084; EC 3.2.2.-; HMM-score: 85.6)DNA metabolism DNA replication, recombination, and repair 8-oxoguanine DNA-glycosylase (ogg) (TIGR00588; EC 3.2.2.-; HMM-score: 30.5)
- TheSEED :
- Endonuclease III (EC 4.2.99.18)
Cell Division and Cell Cycle Cell Division and Cell Cycle - no subcategory Control of cell elongation - division cycle in Bacilli Endonuclease III (EC 4.2.99.18)and 1 more - PFAM: HHH (CL0198) HhH-GPD; HhH-GPD superfamily base excision DNA repair protein (PF00730; HMM-score: 83.4)and 3 moreHHH; Helix-hairpin-helix motif (PF00633; HMM-score: 38.4)HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 17.6)no clan defined TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit (PF08626; HMM-score: 11.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.78
- Cytoplasmic Membrane Score: 8.16
- Cellwall Score: 0.06
- Extracellular Score: 0.01
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9657
- Cytoplasmic Membrane Score: 0.0057
- Cell wall & surface Score: 0.0025
- Extracellular Score: 0.026
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.049045
- TAT(Tat/SPI): 0.009167
- LIPO(Sec/SPII): 0.003281
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CAR68979 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQTTDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDFDGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPLEVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYP
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1135 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]