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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 06-FEB-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F15300 [new locus tag: SPN23F_RS07730 ]
- pan locus tag?: PNEUPAN000126000
- symbol: hol
- pan gene symbol?: hol
- synonym:
- product: antiholin
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F15300 [new locus tag: SPN23F_RS07730 ]
- symbol: hol
- product: antiholin
- replicon: chromosome
- strand: -
- coordinates: 1488824..1489156
- length: 333
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: FM211187 (1488824..1489156) NCBI
- BioCyc: see SPN23F_RS07730
- MicrobesOnline: 5831352 MicrobesOnline
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301ATGCAACAAATTACTGAAATCATCATTGCTTTTGCGACAAGCTTTTTAACAGTAGCAGTA
GGCGGTATTGTAAAAGCAGTAAAAGATTATCTTTTGCGTAAAGGCGGAGAGAAAGCGGTG
ATCATCGCTGAAATTCTAGCTAAAAATGCAGTTCATGCCGTTGAGCAAGTAGCTTCAGAG
ACTGGCTATAAGGGCGAAGAAAAGCTGGAGCAGGCTCGTGCTAAAGTCCGTGCTGAGCTT
ACAAAATACAATATTAGTATGACTGACAAAGACTTAGACACCTTCGTAGAGTCAGCAGTG
AAGCAGATGAATGACGCATGGAAAGGACGATAG60
120
180
240
300
333
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F15300 [new locus tag: SPN23F_RS07730 ]
- symbol: Hol
- description: antiholin
- length: 110
- theoretical pI: 8.90779
- theoretical MW: 12100.9
- GRAVY: -0.0890909
⊟Function[edit | edit source]
- TIGRFAM: Mobile and extrachromosomal element functions Prophage functions phage holin, LL-H family (TIGR01673; HMM-score: 53.6)and 2 moreSignal transduction Other diguanylate cyclase (GGDEF) domain (TIGR00254; HMM-score: 12.9)Regulatory functions Small molecule interactions diguanylate cyclase (GGDEF) domain (TIGR00254; HMM-score: 12.9)
- TheSEED :
- Phage holin
- PFAM: no clan defined Phage_holin_6_1; Bacteriophage holin of superfamily 6 (Holin_LLH) (PF09682; HMM-score: 90.2)and 1 moreFrhB_FdhB_N; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term (PF04422; HMM-score: 15.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helix: 1
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.327455
- TAT(Tat/SPI): 0.006375
- LIPO(Sec/SPII): 0.019643
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CAR69310 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAEILAKNAVHAVEQVASETGYKGEEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQMNDAWKGR
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SPN23F15290 < hol < SPN23F15310 < SPN23F15320 < SPN23F15330 < SPN23F15340 < SPN23F15350 < SPN23F15360 < SPN23F15370 < SPN23F15380 < SPN23F15390 < SPN23F15400 < SPN23F15410 < SPN23F15420 < SPN23F15430 < SPN23F15440 < SPN23F15450 < SPN23F15460 < SPN23F15470 < SPN23F15490 < SPN23F15500 < SPN23F15510
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.