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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS07970 [old locus tags: SPN23F15810 SPN23F_15810 ]
  • pan locus tag?: PNEUPAN000155000
  • symbol: whiA
  • pan gene symbol?: whiA
  • synonym:
  • product: DNA-binding protein WhiA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS07970 [old locus tags: SPN23F15810 SPN23F_15810 ]
  • symbol: whiA
  • product: DNA-binding protein WhiA
  • replicon: chromosome
  • strand: -
  • coordinates: 1526952..1527863
  • length: 912
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAGTTTCACAGTAGCAGTAAAAGAAGAAATCCTGGGCCAACACCATCTGAGCCGGCAT
    GAATTATCTGCCATTATCAAAATGTCTGGTAGCATCGGTCTCTCGACTTCGGGCTTGACT
    TTGTCAGTTGTGACAGAAAATGCCAAACTGGCCCGTCACCTCTATGAGTCCTTTCTCCAT
    TTCTATGAAATCAAATCTGAAATTCGTCACCACCAACGGAGCAATCTTCGCAAGAATCGC
    GTCTATACCGTTTTTACAGATGAAAAGGTGCAGGATTTGTTAAGTGATTTGCACTTGGCA
    GACTCTTTCTTTGGCCTGGAAACAGGTATTGATGAGGCGATTTTATCGGACGAGGAAGCA
    GGTCGTGCCTATCTCTGTGGCGCTTTCTTGGCAAATGGGAGCATTCGTGACCCTGAGTCA
    GGCAAGTACCAGTTGGAAATCAGTTCTGTTTATCTGGACCACGCGCAAGGAATTGCCTCC
    CTTCTCCAACAGTTTTTACTGGATGCCAAGGTGCTTGAGCGCAAGAAGGGGGCTGTGACC
    TATCTCCAGCGAGCAGAAGACATTATGGACTTCTTGATAGTAATAGGAGCCATGCAGGCA
    CGTGATGATTTTGAGCGGGTTAAGATTTTGCGAGAAACCCGTAACGACCTCAATCGGGCT
    AATAATGCCGAGACAGCTAATATCGCTCGGACAGTTTCTGCCAGCATGAAGACCATTAAC
    AATATCAGTAAAATCAAAGATATCATGGGCTTAGAAAATTTGCCAGTAGATTTGCAGGAA
    GTGGCGCAACTGAGGATTCAGCACCCAGACTACTCTATCCAGCAGTTAGCAGATAGTCTC
    AGCACCCCTCTGACCAAAAGTGGTGTCAATCACAGACTCAGAAAAATCAATAAGATAGCG
    GATGAATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS07970 [old locus tags: SPN23F15810 SPN23F_15810 ]
  • symbol: WhiA
  • description: DNA-binding protein WhiA
  • length: 303
  • theoretical pI: 6.59263
  • theoretical MW: 34061.5
  • GRAVY: -0.248845

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division DNA-binding protein WhiA (TIGR00647; HMM-score: 388)
  • TheSEED: see SPN23F15810
  • PFAM:
    Homing_endonuc (CL0324) LAGLIDADG_WhiA; WhiA LAGLIDADG-like domain (PF14527; HMM-score: 111)
    HTH (CL0123) HTH_WhiA; WhiA C-terminal HTH domain (PF02650; HMM-score: 106.2)
    Homing_endonuc (CL0324) WhiA_N; WhiA N-terminal LAGLIDADG-like domain (PF10298; HMM-score: 97.4)
    and 3 more
    LAGLIDADG_3; LAGLIDADG-like domain (PF14528; HMM-score: 23.7)
    l-integrase_N (CL0469) Phage_int_SAM_2; Phage integrase, N-terminal (PF12834; HMM-score: 17.7)
    DNA-mend (CL0382) Integrase_2; Putative integrase (PF13009; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.031367
    • TAT(Tat/SPI): 0.120228
    • LIPO(Sec/SPII): 0.0039
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVVTENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADSFFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIASLLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLNRANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQLADSLSTPLTKSGVNHRLRKINKIADEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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