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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
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serotype 6A
70585
serotype 5
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A66
serotype 3
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ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
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HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
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INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
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R6
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SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS08455 [old locus tags: SPN23F16770 SPN23F_16770 ]
  • pan locus tag?: PNEUPAN003073000
  • symbol: SPN23F_RS08455
  • pan gene symbol?: nanA_2
  • synonym:
  • product: dihydrodipicolinate synthase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS08455 [old locus tags: SPN23F16770 SPN23F_16770 ]
  • symbol: SPN23F_RS08455
  • product: dihydrodipicolinate synthase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1616449..1617366
  • length: 918
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCAGATTTGAAAAAATACGAAGGTGTCATTCCAGCCTTCTACGCATGTTATGATGAG
    CAAGGAGAAGTAAGTCCAGAGCGTACGCGTGCCTTGGTTCAATACTTCATTGATAAAGGT
    GTTCAAGGTCTTTATGTCAATGGTTCTTCTGGTGAATGTATCTACCAAAGCGTTGAAGAT
    CGCAAGTTGATTTTGGAAGAAGTCATGGCGGTAGCCAAAGGTAAATTGACCATTATTGCC
    CATGTTGCTTGCAATAATACTAAAGATAGTATGGAACTTGCTCGCCATGCTGAAAGCTTG
    GGAGTAGATGCTATTGCAACGATTCCACCAATTTACTTCCGCTTGCCAGAATACTCAGTT
    GCCAAATACTGGAACGATATTAGTTCTGCAGCTCCAAACACAGACTACGTGATTTACAAC
    ATTCCTCAATTGGCAGGGGTTGCTTTGACTTCAAGCCTTTACACAGAAATGTTGAAAAAT
    CCTCGTGTTATCGGTGTTAAGAACTCTTCAATGCCAGTTCAAGATATCCAAACCTTTGTC
    AGCCTTGGCGGGGAAGACCATATTGTCTTTAACGGTCCAGATGAACAGTTCCTAGGTGGC
    CGCCTCATGGGTGCTAAGGCTGGTATCGGTGGTACTTATGGTGCTATGCCAGAACTCTTC
    TTGAAACTCAATCAGTTGATTGCGGATAAAGATTTAGAAACAGCGCGTGAATTGCAGTAT
    GCTATCAACGCAATCATTGGTAAACTCACTGCTGCACATGGAAATATGTACGGTGTCATC
    AAAGAAGTTTTGAAGATCAATGAAGGCTTGAATATTGGTTCTGTTCGTTCACCATTGACA
    CCAGTGACTGAAGACGATCGTCCAGTTGTAGAAGCGGCTGCAGCCTTGATTCGTGAAACC
    AAGGAGCGCTTCCTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    918

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS08455 [old locus tags: SPN23F16770 SPN23F_16770 ]
  • symbol: SPN23F_RS08455
  • description: dihydrodipicolinate synthase family protein
  • length: 305
  • theoretical pI: 4.84514
  • theoretical MW: 33371
  • GRAVY: -0.0452459

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides N-acetylneuraminate lyase (TIGR00683; EC 4.1.3.3; HMM-score: 195)
    Metabolism Central intermediary metabolism Amino sugars N-acetylneuraminate lyase (TIGR00683; EC 4.1.3.3; HMM-score: 195)
    and 3 more
    Metabolism Amino acid biosynthesis Aspartate family 4-hydroxy-tetrahydrodipicolinate synthase (TIGR00674; EC 4.3.3.7; HMM-score: 128.9)
    2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (TIGR02313; EC 4.1.2.-; HMM-score: 98.5)
    5-dehydro-4-deoxyglucarate dehydratase (TIGR03249; EC 4.2.1.41; HMM-score: 57.2)
  • TheSEED: see SPN23F16770
  • PFAM:
    TIM_barrel (CL0036) DHDPS; Dihydrodipicolinate synthetase family (PF00701; HMM-score: 198.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012993
    • TAT(Tat/SPI): 0.000749
    • LIPO(Sec/SPII): 0.01854
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001281530 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGLYVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGVDAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKNPRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPELFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVRSPLTPVTEDDRPVVEAAAALIRETKERFL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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