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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-NOV-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS08030 [old locus tag: SPT_1615 ]
  • pan locus tag?: PNEUPAN003073000
  • symbol: SPT_RS08030
  • pan gene symbol?: nanA_2
  • synonym:
  • product: dihydrodipicolinate synthase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS08030 [old locus tag: SPT_1615 ]
  • symbol: SPT_RS08030
  • product: dihydrodipicolinate synthase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1537365..1538282
  • length: 918
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012469 (1537365..1538282) NCBI
  • BioCyc: SPT_RS08030 BioCyc
  • MicrobesOnline: see SPT_1615
  • PneumoBrowse for strain D39V: SPV_2375 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCAGATTTGAAAAAATACGAAGGTGTCATTCCAGCCTTCTACGCATGTTATGATGAT
    CAAGGAGAAGTAAGTCCAGAGCGTACGCGTGCCTTGGTTCAATACTTCATTGATAAAGGT
    GTTCAAGGTCTTTATGTCAATGGTTCTTCTGGTGAATGTATCTACCAAAGCGTTGAAGAT
    CGCAAGTTAATTTTGGAAGAAGTCATGGCAGTTGCCAAGGGTAAATTGACCATCATTGCT
    CACGTTGCTTGCAACAATACCAAAGATAGTATGGAACTTGCTCGCCACGCAGAAAGCTTG
    GGTGTAGATGCCATTGCAACGATTCCACCAATTTACTTCCGCTTGCCAGAATACTCAGTT
    GCTAAATATTGGAACGATATCAGTTCTGCAGCTCCAAATACAGACTACGTGATTTATAAC
    ATTCCTCAATTGGCAGGGGTTGCTTTGACTCCAAGCCTTTACACAGAAATGTTAAAAAAT
    CCACGTGTTATCGGTGTTAAAAATTCTTCAATGCCAGTTCAAGATATCCAAACCTTTGTG
    AGCCTTGGTGGGGAAGATCATATCGTCTTTAATGGTCCAGATGAACAGTTCCTAGGTGGC
    CGCCTTATGGGTGCTAAGGCTGGTATCGGTGGTACTTATGGTGCTATGCCAGAACTCTTC
    TTGAAACTCAATCAGTTGATTGCTGACAAGGACTTGGAAACAGCGCGTGAGTTGCAGTAT
    GCTATCAATGCTATCATTGGTAAACTCACTGCTGCACATGGAAATATGTACGGTGTCATC
    AAAGAAGTTTTGAAAATCAATGAAGGCTTGAATATTGGTTCTGTTCGTTCACCATTGACA
    CCAGTGACTGAAGAAGATCGCCCAGCTGTAGAAGCAGCTGCAGCCTTGATTCGTGAAACC
    AAGGAGCGCTTCCTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    918

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_RS08030 [old locus tag: SPT_1615 ]
  • symbol: SPT_RS08030
  • description: dihydrodipicolinate synthase family protein
  • length: 305
  • theoretical pI: 4.84514
  • theoretical MW: 33353
  • GRAVY: -0.0557377

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides N-acetylneuraminate lyase (TIGR00683; EC 4.1.3.3; HMM-score: 194.1)
    Metabolism Central intermediary metabolism Amino sugars N-acetylneuraminate lyase (TIGR00683; EC 4.1.3.3; HMM-score: 194.1)
    and 3 more
    Metabolism Amino acid biosynthesis Aspartate family 4-hydroxy-tetrahydrodipicolinate synthase (TIGR00674; EC 4.3.3.7; HMM-score: 130.4)
    2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (TIGR02313; EC 4.1.2.-; HMM-score: 99.6)
    5-dehydro-4-deoxyglucarate dehydratase (TIGR03249; EC 4.2.1.41; HMM-score: 58.2)
  • TheSEED: see SPT_1615
  • PFAM:
    TIM_barrel (CL0036) DHDPS; Dihydrodipicolinate synthetase family (PF00701; HMM-score: 202.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013157
    • TAT(Tat/SPI): 0.000737
    • LIPO(Sec/SPII): 0.019674
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001281494 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGLYVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGVDAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKNPRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPELFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVRSPLTPVTEEDRPAVEAAAALIRETKERFL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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