PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 26-AUG-2017

⊟Summary

• organism: Streptococcus pneumoniae SPN994039
• locus tag: SPN994039_09680 [new locus tag: SPN994039_RS05195 ]
• pan locus tag^?: PNEUPAN002213000
• symbol: ftsW
• pan gene symbol^?: ftsW
• synonym:
• product: putative cell division protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPN994039_09680 [new locus tag: SPN994039_RS05195 ]
• symbol: ftsW
• product: putative cell division protein
• replicon: chromosome
• strand: +
• coordinates: 972427..973656
• length: 1230
• essential: unknown other strains

⊟Accession numbers

• Location: FQ312044 (972427..973656) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0952 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  
  ATGAAGATTAGTAAGAGGCACTTATTAAATTATTCCATCTTGATTCCCTACTTGCTTTTA
  TCTATTTTGGGCTTGATTGTGGTCTATTCGACCACCAGTGCTATTTTAATTGAAGAAGGT
  AAGAGCGCCTTGCAGTTGGTTCGAAACCAAGGAATCTTTTGGATTGTTAGTTTGATACTG
  ATTGCCTTAATTTATAAATTGAGACTAGATTTTTTGAGAAATGAGCGACTAATCATTTTA
  GTTATATTAATAGAAATGCTTTTATTGTTCTTGGCTCGTTTTATTGGTATTTCCGTAAAC
  GGGGCATACGGTTGGATTTCGGTTGCAGGAGTAACTATTCAGCCAGCTGAGTACTTAAAA
  ATCATTATTATTTGGTATTTAGCTCACCGATTCTCCAAACAGCAAGAAGAAATAGCTACT
  TATGATTTTCAAGTTTTGACTCAAAATCAATGGCTTCCCCGTGCTTTTAATGATTGGCGA
  TTCGTTCTCCTAGTTCTGATTGGAAGTTTGGGAATTTTCCCTGATTTAGGAAATGCGACT
  ATTTTAGTCTTGGTTTCCTTGATTATGTATACAGTTAGTGGAATCGCTTATCGCTGGTTT
  TCAACTATTCTGGCACTCGTATCTGCCACTTCTGTCTTTGTCTTGACCACTATCAGCCTA
  ATCGGTGTTGAGACCTTTTCAAAAATTCCAGTATTTGGCTATGTAGCCAAGCGCTTTAGT
  GCCTTTTTTAATCCTTTTGCCGATCGTGCTGATGCAGGTCACCAGTTAGCTAATTCTTAT
  TTTGCCATGGTCAATGGCGGTTGGTTTGGTCTAGGTCTTGGAAACTCGATTGAAAAACGA
  GGTTATTTGCCAGAAGCTCATACAGACTTTGTCTTTTCTATCGTGATTGAAGAATTTGGC
  TTTGTTGGTGCCAGTCTTATTTTAGCTCTCTTGTTTTTCATGATTTTGCGGATTATCTTG
  GTCGGTATCCGAGCGGAGAATCCTTTCAATGCCATGGTTGCACTCGGTGTCGGAGGGATG
  ATGTTGGTTCAGGTATTTGTCAATATCGGAGGGATTTCGGGCTTGATTCCATCTACAGGA
  GTGACTTTCCCCTTCTTATCCCAGGGTGGAAATAGTCTTCTAGTCTTATCAGTGGCAGTA
  GCCTTTGTCTTAAATATTGATGCCAGTGAAAAACGCGCTAAGTTGTACCGAGAATTGGAA
  AATCAACCAATGAACCTTCTGTTGAAGTAG
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1230
  

⊟Protein

⊟General

• locus tag: SPN994039_09680 [new locus tag: SPN994039_RS05195 ]
• symbol: FtsW
• description: putative cell division protein
• length: 409
• theoretical pI: 9.59959
• theoretical MW: 45464.7
• GRAVY: 0.822983

⊟Function

• TIGRFAM:
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan cell division protein FtsW (TIGR02614; HMM-score: 288.9)
  Cellular processes Cellular processes Cell division cell division protein FtsW (TIGR02614; HMM-score: 288.9)
  and 4 more
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein RodA (TIGR02210; HMM-score: 221.7)
  Cellular processes Cellular processes Cell division rod shape-determining protein RodA (TIGR02210; HMM-score: 221.7)
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan stage V sporulation protein E (TIGR02615; HMM-score: 216.6)
  Cellular processes Cellular processes Sporulation and germination stage V sporulation protein E (TIGR02615; HMM-score: 216.6)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  Membrane_trans (CL0142) FTSW_RODA_SPOVE; Cell cycle protein (PF01098; HMM-score: 265.2)
  and 1 more
  TIM_barrel (CL0036) ALAD; Delta-aminolevulinic acid dehydratase (PF00490; HMM-score: 11.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 8
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.03164
  • TAT(Tat/SPI): 0.000529
  • LIPO(Sec/SPII): 0.033166
• predicted transmembrane helices (TMHMM): 8

⊟Accession numbers

• GI:
• RefSeq: CCP34662 NCBI
• UniProt:

⊟Protein sequence

• MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWRFVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTISLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELENQPMNLLLK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_0952 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications