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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994039
  • locus tag: SPN994039_RS05185 [old locus tag: SPN994039_09660 ]
  • pan locus tag?: PNEUPAN002057000
  • symbol: SPN994039_RS05185
  • pan gene symbol?: pepE
  • synonym:
  • product: Type 1 glutamine amidotransferase-like domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN994039_RS05185 [old locus tag: SPN994039_09660 ]
  • symbol: SPN994039_RS05185
  • product: Type 1 glutamine amidotransferase-like domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 970752..971339
  • length: 588
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021005 (970752..971339) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGGTGGGAATCCCCCAATAAAGAAATATAGTATTGTTGATAAAATTGTATTATCAACC
    AAGATTAAAAGAATTATCATTTTTACAGTTTTTCGAGAAAATTGGGAACCGTACATGAAA
    AAGTACACGGAAGTTTTTCAAAGTCAATTTCCTAATCTAAACATTGATTACTTGCTCCTG
    GACACTGAGCAGATTGATCTTGATAGCTATCTAGATGCTGATCTAATTATCATCGGTGGT
    GGAAATACGGAAAAATATATAGCTACTTATGTCAATCAGGAGTTCAAAAATTATATTGAT
    CATATGCTTAACAAAGGGGCGAAAGTTATAGGGTTTTCTGCAGGAGCCCTATTATTAGGA
    GAAAAAGTCTACGTCTCACCTAACGATAATTCAGATCATCAGATAAAGATAAAAGATGGA
    TTAGGACTCTTTAGTCAGTTTTTAATTAGTGTCTATTATGATTCATGGAATGATAAAGCA
    AATAAGGATAGAGCTGAAGAACTCGTTAATGTTCCCATAATTCCACTAAATGATCATTCA
    TGTCTTGTATTAGATAAACTTGGAAACATTATTGAGAAAATTGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    588

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN994039_RS05185 [old locus tag: SPN994039_09660 ]
  • symbol: SPN994039_RS05185
  • description: Type 1 glutamine amidotransferase-like domain-containing protein
  • length: 195
  • theoretical pI: 4.88214
  • theoretical MW: 22256.4
  • GRAVY: -0.170769

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Other cyanophycinase (TIGR02069; EC 3.4.15.6; HMM-score: 35.2)
    and 1 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin cobyric acid synthase CobQ (TIGR00313; EC 6.3.5.10; HMM-score: 17.5)
  • TheSEED:
  • PFAM:
    Glutaminase_I (CL0014) Peptidase_S51; Peptidase family S51 (PF03575; HMM-score: 52.3)
    and 3 more
    GATase_3; CobB/CobQ-like glutamine amidotransferase domain (PF07685; HMM-score: 31.2)
    BPL_N; Biotin-protein ligase, N terminal (PF09825; HMM-score: 15.6)
    no clan defined ARL2_Bind_BART; The ARF-like 2 binding protein BART (PF11527; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00082
    • TAT(Tat/SPI): 0.000081
    • LIPO(Sec/SPII): 0.000277
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_061634172 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTEVFQSQFPNLNIDYLLLDTEQIDLDSYLDADLIIIGGGNTEKYIATYVNQEFKNYIDHMLNKGAKVIGFSAGALLLGEKVYVSPNDNSDHQIKIKDGLGLFSQFLISVYYDSWNDKANKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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