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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_00580 [new locus tag: SPNA45_RS03335 ]
  • pan locus tag?: PNEUPAN003077000
  • symbol: SPNA45_00580
  • pan gene symbol?: divIVA
  • synonym:
  • product: putative cell-division protein DivIVA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_00580 [new locus tag: SPNA45_RS03335 ]
  • symbol: SPNA45_00580
  • product: putative cell-division protein DivIVA
  • replicon: chromosome
  • strand: +
  • coordinates: 575333..576067
  • length: 735
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGCCAATTACATCATTAGAAATAAAGGACAAGACTTTTGGAACTCGATTCAGAGGTTTT
    GATCCAGAAGAAGTCGATGAATTTTTAGATATTGTGGTTCGTGATTACGAAGCTCTTGTG
    CGTGCGAATCATGATAAAAATTTGCGTGTTAAGAGTTTAGAAGAGCGTTTGTCTTACTTT
    GATGAAATAAAAGATTCATTGAGCCAGTCTGTATTGATTGCTCAGGATACAGCTGAGAGA
    GTGAAACAGGCGGCGCATGAACGTTCAAACAATATCATTCATCAAGCAGAGCAAGATGCG
    CAACGCTTGTTGGAAGAAGCTAAATATAAGGCAAACGAGATTCTTCGTCAAGCAACTGAT
    AATGCTAAGAAAGTCGCTGTTGAAACAGAAGAATTGAAGAACAAGAGCCGTGTCTTCCAC
    CAACGTCTCAAATCTACAATTGAGAGTCAGTTGGCTATTGTTGAATCTTCAGATTGGGAA
    GATCTTCTCCGTCCAACAGCTACTTATCTTCAAACCAGTGATGAAGCCTTTAAAGAAGTG
    GTTAGCAAAGTACTTGGAGAACCGATTCCAGCTCCAATTGAAGAAGAACCAATTGATATG
    ACACGTCAGTTCTCTCAAGCAGAAATGGCAGAGTTACAAGCTCGTATTGAGGTAGCCGAT
    AAAGAATTGGCTGAATTTGAAGCTCAGATTAAACAGGAAGTGGAAGCTCCAACTTGTAGT
    GAGTCCTCAGGTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    735

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_00580 [new locus tag: SPNA45_RS03335 ]
  • symbol: SPNA45_00580
  • description: putative cell-division protein DivIVA
  • length: 244
  • theoretical pI: 4.42565
  • theoretical MW: 27867.9
  • GRAVY: -0.647951

⊟Function[edit | edit source]

  • TIGRFAM:
    DivIVA domain (TIGR03544; HMM-score: 50)
    and 7 more
    HflK protein (TIGR01933; HMM-score: 23.6)
    ATP synthase archaeal, H subunit (TIGR02926; EC 3.6.3.14; HMM-score: 17.9)
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 14.5)
    flagellar assembly protein FliH (TIGR03825; HMM-score: 10.1)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F0, B subunit (TIGR01144; EC 3.6.3.14; HMM-score: 8.1)
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus protein, HrpE/YscL family (TIGR02499; HMM-score: 4.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus protein, HrpE/YscL family (TIGR02499; HMM-score: 4.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined DivIVA; DivIVA protein (PF05103; HMM-score: 130.9)
    and 14 more
    ATP_synthase (CL0255) HrpE; HrpE/YscL/FliH and V-type ATPase subunit E (PF06188; HMM-score: 21.2)
    no clan defined Med2; Mediator complex subunit 2 (PF11214; HMM-score: 15.9)
    ATP_synthase (CL0255) vATP-synt_E; ATP synthase (E/31 kDa) subunit (PF01991; HMM-score: 15.2)
    no clan defined YlqD; YlqD protein (PF11068; HMM-score: 12.8)
    KfrA_N; Plasmid replication region DNA-binding N-term (PF11740; HMM-score: 11.6)
    ATP_synthase (CL0255) V-ATPase_G_2; Vacuolar (H+)-ATPase G subunit (PF16999; HMM-score: 10.9)
    no clan defined CSN5_C; Cop9 signalosome subunit 5 C-terminal domain (PF18323; HMM-score: 10.4)
    SlyX; SlyX (PF04102; HMM-score: 9.8)
    DUF3135; Protein of unknown function (DUF3135) (PF11333; HMM-score: 9.6)
    Actin_ATPase (CL0108) FtsA; Cell division protein FtsA (PF14450; HMM-score: 9.5)
    ATP_synthase (CL0255) ATP-synt_B; ATP synthase B/B' CF(0) (PF00430; HMM-score: 8.7)
    no clan defined BEX; Brain expressed X-linked like family (PF04538; HMM-score: 8.2)
    YtxH; YtxH-like protein (PF12732; HMM-score: 8)
    ATP_synthase (CL0255) V-ATPase_G; Vacuolar (H+)-ATPase G subunit (PF03179; HMM-score: 7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9909
    • Cytoplasmic Membrane Score: 0.0025
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0066
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001371
    • TAT(Tat/SPI): 0.000171
    • LIPO(Sec/SPII): 0.000285
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM07868 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEALVRANHDKNLRVKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQRLLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWEDLLRPTATYLQTSDEAFKEVVSKVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEVADKELAEFEAQIKQEVEAPTCSESSG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Aurore Fleurie, Sylvie Manuse, Chao Zhao, Nathalie Campo, Caroline Cluzel, Jean-Pierre Lavergne, Céline Freton, Christophe Combet, Sébastien Guiral, Boumediene Soufi, Boris Macek, Erkin Kuru, Michael S VanNieuwenhze, Yves V Brun, Anne-Marie Di Guilmi, Jean-Pierre Claverys, Anne Galinier, Christophe Grangeasse
Interplay of the serine/threonine-kinase StkP and the paralogs DivIVA and GpsB in pneumococcal cell elongation and division.
PLoS Genet: 2014, 10(4);e1004275
[PubMed:24722178] [WorldCat.org] [DOI] (I e)

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