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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS01390 [old locus tag: SPNA45_00227 ]
  • pan locus tag?: PNEUPAN003611000
  • symbol: SPNA45_RS01390
  • pan gene symbol?: diiA
  • synonym:
  • product: DUF1542 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS01390 [old locus tag: SPNA45_00227 ]
  • symbol: SPNA45_RS01390
  • product: DUF1542 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 237840..238739
  • length: 900
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (237840..238739) NCBI
  • BioCyc: SPNA45_RS01390 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1789 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    TTGGTAGCACAAGATCCAAAAGCACAAGATAGCACTAAACCGACTGCTGAAAAATCAACT
    GTTAAAGCACCTGCTCAAAGAGTAGATGTAAAAGATATAACTCATTTAACAGATGAAGAA
    AAAGAAAAAGTTAAGGTTGCTATTTTACAAGCAAATGGTTCAGCATTAGACGGAGCGACA
    ATCAATGTAGCTGGATATGGTACAGCAACAATCACATTCCCAGATGGTTCAGTAGTGACG
    ATTCTAGGAAAAGATACAGTTCAACAATCTGCGAAAGGTGAATCTGTAACTCAAGAAGCT
    ACACCAGAGTATAAGCTAGAAACTACACCAGGTGGAGATAAGGGAGGCAATACTGGAAGC
    TCAGATGCTAATGCGAATGAAGGCGGTGGTAGCCAGGCGGGTGGATCAGCTCACACAGGT
    TCACAAAACTCAGCTCAATCACAAGCTTCTAAGCAATTAGCTACTGAAAAAGAATCAGCT
    AAAAATGCCATTGAAAAAGCAGCCAAGGACAAGCAGGATGAAATCAAAGGCGCACCGCTT
    TCTGATAAAGAAAAAGCAGAACTTTTAGCAAGAGTGGAAGCAGAAAAACAAGCAGCTCTC
    AAAGAGATTGAAAATGCGAAAACTATGGAAGATGTGAAGGAAGCAGAAACGATTGGAGTG
    CAAGCCATTGTCATGGTTACAGTTCCTAAGAGACCAGTGGCTCTTAATGCTGCTCCTAAG
    ACAACAAGTACACCGCAAGCAACTGCAGGAACAATGCAAGATGTTACCTACCAGTCACCT
    GCTGGCAAACAATTACCTAACACAGGTTCAGCATCAAGTGCAGCACTTGCTAGTCTTGGT
    CTAGCGGCGGCAACAAGTGGTTTTGCTTTGCTAGGAAGAAAGACTAGACGTAGAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS01390 [old locus tag: SPNA45_00227 ]
  • symbol: SPNA45_RS01390
  • description: DUF1542 domain-containing protein
  • length: 299
  • theoretical pI: 7.66425
  • theoretical MW: 30743
  • GRAVY: -0.579264

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 25.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    E-set (CL0159) aRib; Atypical Rib domain (PF18938; HMM-score: 73.1)
    and 5 more
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 57.2)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 33.1)
    P-loop_NTPase (CL0023) AAA_13; AAA domain (PF13166; HMM-score: 12.2)
    B_GA (CL0598) GA; GA module (PF01468; HMM-score: 11.8)
    no clan defined DUF2605; Protein of unknown function (DUF2605) (PF10792; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.0636
    • Cell wall & surface Score: 0.906
    • Extracellular Score: 0.0303
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.030167
    • TAT(Tat/SPI): 0.002025
    • LIPO(Sec/SPII): 0.002249
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000226473 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKVKVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIVMVTVPKRPVALNAAPKTTSTPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLAAATSGFALLGRKTRRRK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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