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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1992 [new locus tag: SP_RS10010 ]
  • pan locus tag?: PNEUPAN003611000
  • symbol: SP_1992
  • pan gene symbol?: diiA
  • synonym:
  • product: cell wall surface anchor family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP_1992 [new locus tag: SP_RS10010 ]
  • symbol: SP_1992
  • product: cell wall surface anchor family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1895473..1896138
  • length: 666
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    GTGACGATTCTAGGAAAAGATACAGTTCAACAATCTGCGAAAGGTGAATCTGTAACTCAA
    GAAGCTACACCAGAGTATAAGCTAGAAAATACACCAGGTGGAGATAAGGGAGGCAATACT
    GGAAGCTCAGATGCTAATGCGAATGAAGGCGGTGGTAGCCAGGCGGGTGGATCAGCTCAC
    ACAGGTTCACAAAACTCAGCTCAATCACAAGCTTCTAAGCAATTAGCTACTGAAAAAGAA
    TCAGCTAAAAATGCCATTGAAAAAGCAGCCAAGGACAAGCAGGATGAAATCAAAGGCGCA
    CCGCTTTCTGATAAAGAAAAAGCAGAACTTTTAGCAAGAGTGGAAGCAGAAAAACAAGCA
    GCTCTCAAAGAGATTGAAAATGCGAAAACTATGGAAGATGTGAAGGAAGCAGAAACGATT
    GGAGTGCAAGCCATTGCCATGGTTACAGTTCCTAAGAGACCAGTGGCTCCTAATGCTGCT
    CCTAAGACAACAAGTGCACCGCAAGCAACTGCAGGAACAATGCAAGATGTTACCTACCAG
    TCACCTGCTGGCAAACAATTACCTAACACAGGTTCAGCATCAAGTGCAGCACTTGCTAGT
    CTTGGTCTAGTGGTGGCAACAAGTGGTTTTGCTTTGCTAGGAAGAAAGACTAGACGTAGA
    AAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    666

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP_1992 [new locus tag: SP_RS10010 ]
  • symbol: SP_1992
  • description: cell wall surface anchor family protein
  • length: 221
  • theoretical pI: 9.38491
  • theoretical MW: 22648
  • GRAVY: -0.672851

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 26)
  • TheSEED  :
    • Cell wall surface anchor family protein
  • PFAM:
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 55.4)
    and 3 more
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 32.4)
    P-loop_NTPase (CL0023) AAA_13; AAA domain (PF13166; HMM-score: 11.1)
    no clan defined DUF2605; Protein of unknown function (DUF2605) (PF10792; HMM-score: 10.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.2014
    • Cell wall & surface Score: 0.7575
    • Extracellular Score: 0.041
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.059552
    • TAT(Tat/SPI): 0.008979
    • LIPO(Sec/SPII): 0.013145
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTRRRK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]