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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 14-DEC-2023
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPNA45
- locus tag: SPNA45_RS08365 [old locus tag: SPNA45_01492 ]
- pan locus tag?: PNEUPAN001508000
- symbol: SPNA45_RS08365
- pan gene symbol?: estA
- synonym:
- product: alpha/beta hydrolase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNA45_RS08365 [old locus tag: SPNA45_01492 ]
- symbol: SPNA45_RS08365
- product: alpha/beta hydrolase
- replicon: chromosome
- strand: -
- coordinates: 1509762..1510541
- length: 780
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_018594 (1509762..1510541) NCBI
- BioCyc: SPNA45_RS08365 BioCyc
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0534 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGGCAGTAATGAAAATCGAGTATTACTCACAAGTATTGGATATGGAGTGGGGGGTGAAT
GTCCTCTACCCTGATGCCAATCGAGTGGAAGAACCAGAGTGTGAAGATATTCCCGTCTTG
TACCTTTTACACGGGATGTCTGGAAATCATAATAGTTGGCTTAAGCGGACCAATGTAGAA
CGCTTGCTTCGAGGAACTAATCTCATCGTTGTTATGCCCAATACCAGCAATGGTTGGTAC
ACCGATACCCAGTATGGTTTTGACTACTACACGGCTCTAGCAGAGGAATTGCCACAGGTT
CTGAAACGCTTCTTCCCTAATATGACTAGCAAGCGTGAAAAGACCTTTATCGCTGGTCTT
TCTATGGGAGGCTACGGCTGCTTCAAACTGGCTCTTGCGACAAATCGTTTTTCTCATGCA
GCTAGCTTTTCAGGTGCATTGAGCTTTCAAGATTTTTCTCCTGAGAGTCAAAATCTGGGA
AGTCCAGCCTACTGGAGAGGTGTTTTTGGAGAGATTAAAGACTGGACAACTAGTCCCTAT
TCTCTTGAAAGTCTGGCTAAAAAATCGGATAAAAAGACCAAACTTTGGGCGTGGTGTGGC
GAACAGGATTTCTTGTACGAAGCCAATAATCTCGCAGTGAAAAATCTCAAAAAACTGGGT
TTTGATGTGACCTATAGCCATAGCGTTGGAACTCACGAGTGGTACTACTGGGAAAAACAA
TTGGAAGTTTTTTTAACAACCCTACCAATTGATTTCAAATTAGAAGAGAGACTGACTTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNA45_RS08365 [old locus tag: SPNA45_01492 ]
- symbol: SPNA45_RS08365
- description: alpha/beta hydrolase
- length: 259
- theoretical pI: 5.6926
- theoretical MW: 29870.7
- GRAVY: -0.367181
⊟Function[edit | edit source]
- reaction: EC 3.-.-.-? ExPASy
- TIGRFAM: Cellular processes Detoxification S-formylglutathione hydrolase (TIGR02821; EC 3.1.2.12; HMM-score: 39.4)and 2 moreFatty acid and phospholipid metabolism Degradation esterase, PHB depolymerase family (TIGR01840; EC 3.1.1.-; HMM-score: 16.3)Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (TIGR03695; EC 4.2.99.20; HMM-score: 14)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: AB_hydrolase (CL0028) Esterase; Putative esterase (PF00756; HMM-score: 71.1)and 5 moreChlorophyllase2; Chlorophyllase enzyme (PF12740; HMM-score: 21.4)Chlorophyllase; Chlorophyllase (PF07224; HMM-score: 20.9)Abhydrolase_6; Alpha/beta hydrolase family (PF12697; HMM-score: 17.8)Abhydrolase_2; Phospholipase/Carboxylesterase (PF02230; HMM-score: 15.9)Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 15.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.8987
- Cytoplasmic Membrane Score: 0.0086
- Cell wall & surface Score: 0.0008
- Extracellular Score: 0.0918
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004623
- TAT(Tat/SPI): 0.000253
- LIPO(Sec/SPII): 0.000477
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000290019 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLHGMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLKRFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLGSPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKKLGFDVTYSHSVGTHEWYYWEKQLEVFLTTLPIDFKLEERLT
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0534 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]