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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS08400 [old locus tag: SPNA45_01498 ]
  • pan locus tag?: PNEUPAN001501000
  • symbol: SPNA45_RS08400
  • pan gene symbol?: nagAa
  • synonym:
  • product: ferredoxin reductase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS08400 [old locus tag: SPNA45_01498 ]
  • symbol: SPNA45_RS08400
  • product: ferredoxin reductase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1518114..1519259
  • length: 1146
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (1518114..1519259) NCBI
  • BioCyc: SPNA45_RS08400 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0527 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAATCAATCAAAGAACTACTCTTTATCATAGCTAGTTTTATCTTGACTCTTTTGACT
    TGGATGAACACTTCTCCCCAATTCATGATTCCAGGACTAGCTTTAACAAGCCTATCTCTG
    ACTTTTATCCTAGCCACTCGTCTCCCACTACTAGAAAGCTGGTTTCACGGTTTGGAGAAG
    GTCTACACCGTCCACAAATTCACAGCCTTTCTCTCAATCATCCTACTAATCTTTCATAAC
    TTTAGTATGGGCGGTTTGTGGGGCTCTCGCTTAGCTGCTCAGTTTGGCAATCTTGCCATC
    TATATCTTTGCCAGCATCATCCTTGTCGCCTATTTAGGCAAATACATCCAATACGAAGCT
    TGGCGATGGATTCACCGCCTGGTTTACCTAGCCTATATTTTAGGACTCTTTCACATCTAC
    ATGATAATGGGCAATCGTCTCCTTACATTTAATCTTCTAAGTTTTCTTGTTGGTAGCTAT
    GCCCTTTTAGGCTTACTAGCTGGTTTTTATATCATTTTTCTATATCAAAAGATTTCCTTC
    CCCTATCTAGGAAAAATTACCCATCTCAAACGCTTAAATCACGATACTAGAGAAATTCAA
    ATCCATCTTAGCAGACCTTTCAACTATCAATCAGGACAATTTGCCTTTCTAAAGATTTTC
    CAAGAAGGCTTTGAAAGTGCTCCGCATCCCTTTTCTATCTCAGGAGGTCATGGTCAAACT
    CTTTACTTTACTATTAAAAATTCAGGCGACCATACCAAGAATATCTATGATAATCTTCAA
    GCCGGCAGCAAAGTAACCCTAGACAGAGCTTACGGACACATGATCATAGAAGAAGGACGA
    GAAAATCAGGTTTGGATTGCTGGAGGTATTGGGATCACCCCCTTCATCTCTTACATCCGT
    GAACATCCTATTTTAGATAAACAGGTTCACTTCTACTATAGCTTCCGTGGAGATGAAAAT
    GCAGTCTACCTAGATTTACTCCGTAACTATGCTCAGAAAAATCCTAATTTTGAACAAAAA
    GAAGTGCCCGAACATGCAACCATCTATATGTGTGGTCCTATTTCTATGATGAAGGCACTT
    GCCAAACAGATTAAGAAACAAAATCCAAAAACAGAGCTTATTTACGAAGGATTCAAGTTC
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1146

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS08400 [old locus tag: SPNA45_01498 ]
  • symbol: SPNA45_RS08400
  • description: ferredoxin reductase family protein
  • length: 381
  • theoretical pI: 9.76304
  • theoretical MW: 43995.2
  • GRAVY: 0.189764

⊟Function[edit | edit source]

  • reaction:
    EC 1.-.-.-?  ExPASy
  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit (TIGR01941; EC 1.6.5.-; HMM-score: 35.5)
    and 2 more
    Metabolism Central intermediary metabolism Sulfur metabolism sulfite reductase, subunit B (TIGR02911; EC 1.8.-.-; HMM-score: 25.7)
    Metabolism Energy metabolism Other phenylacetate-CoA oxygenase/reductase, PaaK subunit (TIGR02160; HMM-score: 21.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    NAD_Ferredoxin (CL0091) NAD_binding_1; Oxidoreductase NAD-binding domain (PF00175; HMM-score: 34.8)
    2heme_cytochrom (CL0328) Ferric_reduct; Ferric reductase like transmembrane component (PF01794; HMM-score: 29.6)
    and 3 more
    FAD_Lum_binding (CL0076) FAD_binding_8; FAD-binding domain (PF08022; HMM-score: 25.9)
    NAD_Ferredoxin (CL0091) NAD_binding_6; Ferric reductase NAD binding domain (PF08030; HMM-score: 22)
    2heme_cytochrom (CL0328) Ni_hydr_CYTB; Prokaryotic cytochrome b561 (PF01292; HMM-score: 7.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9995
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0005
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.12219
    • TAT(Tat/SPI): 0.011708
    • LIPO(Sec/SPII): 0.019666
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000835792 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKSIKELLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLKIFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKNPNFEQKEVPEHATIYMCGPISMMKALAKQIKKQNPKTELIYEGFKFK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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