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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-APR-2017

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu15
  • locus tag: SPNHU15_01278 [new locus tag: SPNHU15_RS06045 ]
  • pan locus tag?: PNEUPAN002493000
  • symbol: SPNHU15_01278
  • pan gene symbol?: ftsY
  • synonym:
  • product: cell division protein FtsY

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU15_01278 [new locus tag: SPNHU15_RS06045 ]
  • symbol: SPNHU15_01278
  • product: cell division protein FtsY
  • replicon: chromosome
  • strand: -
  • coordinates: 1216917..1218194
  • length: 1278
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: CP020551 (1216917..1218194) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1101 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTA
    AAAGAAGCTCTGGAAAATCTTGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTT
    GAGGAAGTTTCTCAGGAAGAAGCAGAGGTTGAAATTGTTGAACAAGCTGTGTTCCAAGAA
    GAGGAAATCCAAGACACAGTTGAAGAAAGTCTGGATTTAGAGCCAGTTATAGAAGTTTCT
    CAAAAAGAAGTCAAAGAATTTCCACACTCAGAAGAAGGGAATACTGAGTTTCTAGAGACT
    GTAGAAGAAAATAATTCTGAAGTTCTTGAAGCAGAAAGGCCTCAAACAGAAGAAACTGTT
    CAGGAAAAATATGACCGCAGTCTTAAGAAAACTCGCACAGGTTTCGGTGCCCGCTTGAAT
    GCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAACTGGAAGAACTG
    TTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAGGAACTACGTTAC
    GAAGCCAAGCTTGAAAATGCCAAGAAACCTGATGCACTTCGTCGTGTCATCATTGAGAAA
    TTGGTTGAGCTTTATGAAAAGGATGGTAGCTACGATGAAAGCATCCACTTCCAAGATAAC
    TTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACTTCTATCGGAAAA
    CTAGCTCACCGCTACAAACGAGCTGGTAAGAAGGTCATGCTGGTTGCAGCAGATACCTTC
    CGTGCGGGTGCAGTAGCTCAGCTAGCTGAATGGGGCCGACGAGTAGATGTTCCAGTAGTA
    ACTGGACCTGAAAAAGCTGATCCAGCCAGCGTGGTCTTTGATGGTATGGAACGTGCCGTG
    GCTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAAAATAAGGATAAC
    CTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTGCCAGAAGCACCA
    CATGAAACCTTCTTGGCACTTGATGCATCAACAGGTCAAAATGCCCTAGTACAGGCCAAA
    GAATTTTCGAAAATCACACCTTTAACGGGAATTGTTTTGACTAAGATTGATGGAACTGCT
    CGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTAAAATTGATTGGT
    TTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTCATGAAAGGTCTC
    TTGGAAGGTTTAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1278

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPNHU15_01278 [new locus tag: SPNHU15_RS06045 ]
  • symbol: SPNHU15_01278
  • description: cell division protein FtsY
  • length: 425
  • theoretical pI: 4.21955
  • theoretical MW: 47497.3
  • GRAVY: -0.305176

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle-docking protein FtsY (TIGR00064; HMM-score: 353.6)
    and 12 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal recognition particle protein (TIGR00959; HMM-score: 211)
    signal recognition particle protein SRP54 (TIGR01425; HMM-score: 171.8)
    Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 83.5)
    Genetic information processing Protein fate Protein modification and repair hydrogenase accessory protein HypB (TIGR00073; HMM-score: 23.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 18.7)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 18.7)
    arsenical pump-driving ATPase (TIGR04291; EC 3.6.1.-; HMM-score: 14.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions dTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 12.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids capsular exopolysaccharide family (TIGR01007; HMM-score: 12.9)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 12.7)
    Hypothetical proteins Conserved transport-energizing ATPase, TRC40/GET3/ArsA family (TIGR00345; EC 3.6.1.-; HMM-score: 12)
    cell division ATPase MinD (TIGR01969; HMM-score: 7.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    P-loop_NTPase (CL0023) SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 251.9)
    and 23 more
    no clan defined SRP54_N; SRP54-type protein, helical bundle domain (PF02881; HMM-score: 48.9)
    P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 23.4)
    CbiA; CobQ/CobB/MinD/ParA nucleotide binding domain (PF01656; HMM-score: 22.3)
    AAA_22; AAA domain (PF13401; HMM-score: 19.5)
    MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 18.4)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 17.6)
    AAA_31; AAA domain (PF13614; HMM-score: 16.3)
    AAA_25; AAA domain (PF13481; HMM-score: 16.1)
    AAA_33; AAA domain (PF13671; HMM-score: 15.2)
    AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 14.6)
    ArsA_ATPase; Anion-transporting ATPase (PF02374; HMM-score: 14.4)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 14.2)
    Thymidylate_kin; Thymidylate kinase (PF02223; HMM-score: 13.8)
    Fer4_NifH; 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family (PF00142; HMM-score: 13.3)
    no clan defined ATP-cone; ATP cone domain (PF03477; HMM-score: 13.3)
    P-loop_NTPase (CL0023) AAA_19; AAA domain (PF13245; HMM-score: 13.2)
    AAA_15; AAA ATPase domain (PF13175; HMM-score: 13)
    YqeC; YqeC protein (PF19842; HMM-score: 12.9)
    ABC_tran; ABC transporter (PF00005; HMM-score: 12.5)
    MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 12.1)
    AAA_23; AAA domain (PF13476; HMM-score: 11.9)
    ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 9)
    AAA_17; AAA domain (PF13207; HMM-score: 9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5462
    • Cytoplasmic Membrane Score: 0.409
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0439
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002809
    • TAT(Tat/SPI): 0.000153
    • LIPO(Sec/SPII): 0.000246
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ARD37058 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVEENNSEVLEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]