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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-APR-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu15
  • locus tag: SPNHU15_01489 [new locus tag: SPNHU15_RS07050 ]
  • pan locus tag?: PNEUPAN002736000
  • symbol: SPNHU15_01489
  • pan gene symbol?: capA
  • synonym:
  • product: poly-gamma-glutamate biosynthesis enzyme

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU15_01489 [new locus tag: SPNHU15_RS07050 ]
  • symbol: SPNHU15_01489
  • product: poly-gamma-glutamate biosynthesis enzyme
  • replicon: chromosome
  • strand: -
  • coordinates: 1408866..1409582
  • length: 717
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP020551 (1408866..1409582) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGCCCACGGGGATTTGCTCTACCACGATGGACTTTTCTTTTCAGCTAAAAAAGAAGAC
    GGTACCTATGACTTTCATGAAAATTTTGAGTATGTGACTCCTTGGCTCAAGCAAGCAGAT
    TTAGCTATTGGTGATTTTGAAGGAACCATTAATAAGGATCATTATTTAGCGGGTTATCTT
    CTCTTTAATGCTCCTGTTGAAGTTATGGATGCTATTAAGGAGGCAGGTTATCATGTGCTG
    GATTTAGCTCATAATCATATTTTGGATTCGCAAATTGAGGGAGTTATTTCAACGGCCGAT
    ATTATTGAGAAAGCTGGAATCACTCCAATCGGAGTTTATACGCACGAACCACGTGTTCAG
    GCTCCGCTGGTCATTAAGGAAGTGAATGGTATCAAGGTTGCATTGTTAGCCTATTCCTAT
    GGTTTCAATGGAATTGAGCAGTATATTTCTAAGGAAGACTATAATCGTTATCTTTCAGAT
    TTAAACGAAGATAAGATGAAGGCTGAAATTGAACGGGCAGAGAAGGAAGCAGATATCACC
    ATTATCATGCTTCAGATGGGTGTTGAGTATCGATTGGAACCAACTGAAGAACAAAAAGCT
    CTTTATCACAAGATGATCGATTGGGGAGCGGATATTATCTTTGGAGGGCATCCTCACGTT
    GTTGAACCATCTGAAATGGTTGAAAAAGATGGAGATAAGAAACTCATTATCTATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    717

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU15_01489 [new locus tag: SPNHU15_RS07050 ]
  • symbol: SPNHU15_01489
  • description: poly-gamma-glutamate biosynthesis enzyme
  • length: 238
  • theoretical pI: 4.48154
  • theoretical MW: 27039.4
  • GRAVY: -0.265966

⊟Function[edit | edit source]

  • TIGRFAM:
    thiosulfohydrolase SoxB (TIGR04486; HMM-score: 17.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Calcineurin (CL0163) PGA_cap; Bacterial capsule synthesis protein PGA_cap (PF09587; HMM-score: 206)
    and 2 more
    HTH (CL0123) HTH_OrfB_IS605; Helix-turn-helix domain (PF12323; HMM-score: 15.4)
    NADP_Rossmann (CL0063) Semialdhyde_dh; Semialdehyde dehydrogenase, NAD binding domain (PF01118; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5413
    • Cytoplasmic Membrane Score: 0.0256
    • Cell wall & surface Score: 0.0586
    • Extracellular Score: 0.3745
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003241
    • TAT(Tat/SPI): 0.000172
    • LIPO(Sec/SPII): 0.000562
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ARD37258 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIGDFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSDLNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHPHVVEPSEMVEKDGDKKLIIY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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