PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 03-APR-2017

⊟Summary

• organism: Streptococcus pneumoniae Hu15
• locus tag: SPNHU15_02120 [new locus tag: SPNHU15_RS10075 ]
• pan locus tag^?: PNEUPAN003760000
• symbol: SPNHU15_02120
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU15_02120 [new locus tag: SPNHU15_RS10075 ]
• symbol: SPNHU15_02120
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 1988272..1989210
• length: 939
• essential: unknown

⊟Accession numbers

• Location: CP020551 (1988272..1989210) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  ATGGAGAACAAATTTGTAGAATTTATCGAAAACAATAAAAAAGTAATCATTTCATCAGTT
  GCAGTTGGTGTTGTATTGGTATTAGGGTTTGGATGGTATTCATATAACCAACAACAAGCA
  GAACAACAAGCAAAAATTGTACAATTAGAAAAAGATAGCAAATCAGACAAAGAACAAGTT
  GATAAACTATTTGAATCATTTGATGCATCTTCAGATGAATCTATTTCTAAATTAAAAGAA
  CTATCTGAAACTTCACTTAAAACCGATGCAGGTAAAGACTATCTTAATAACAAAGTCAAA
  GAATCATCTAAAGCAATTGTAGATTTTCATTTGCAAAAAGGTTTGGCTTATGATGTTAAA
  GATTCAGATGACAAATTTAAAGATAAAGCAACTCTTGAAACAAATGTGAAAGAAATTAAT
  AAGCAAATTGATTTTATCAAAAAAGTTGATAAAACCTTTAAACAGGAGAATTTGGAAGAA
  ACTCTTAAATCTCTAAATGATATTGTTGATAAATATCAAAAACAAATCGAAATTTTGAAG
  AAACAAGAAGAAGAAAAAGCTGCTAAAAAAGCAAAAGAATCTTCTAGTCAAAGTAATTCT
  TCTGGTCGTGCTTCTAATGAGTCTTATAATGGTTCTTCTAATTCAAATGTAGATTATAGT
  TCATCTGAACAAACTAATAGATATTCGAATAATTATGGCGGTCAAGATTATTCTAGTTCT
  GGAAATAGTTCAACAAATGGTGGATCATCAGAACAATATTCATCTAGCAATTCAAACAGC
  GGAGTAAATAATGGCTACTATACAAAATATAAGAATATTGGTGCTGATGGATATGTAAGA
  GATACTTACCATAATGAGAGCAATGGAGATGTGTTTGACGAAAATGGGAATTATCTTGGA
  AACACTGGGGGAGGCATTGCAGAACCTCCACAACGATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  939
  

⊟Protein

⊟General

• locus tag: SPNHU15_02120 [new locus tag: SPNHU15_RS10075 ]
• symbol: SPNHU15_02120
• description: hypothetical protein
• length: 312
• theoretical pI: 4.80587
• theoretical MW: 34751.4
• GRAVY: -1.06058

⊟Function

• TIGRFAM:
  early transcribed membrane protein (ETRAMP) family (TIGR01495; HMM-score: 14.6)
  Signal transduction Regulatory functions Protein interactions Phr family secreted Rap phosphatase inhibitor (TIGR04429; HMM-score: 12.5)
  and 1 more
  phage lysis regulatory protein, LysB family (TIGR03495; HMM-score: 10.2)
• TheSEED: data available for Hungary19A-6, TIGR4
• PFAM:
  TPR (CL0020) TPR_21; Tetratricopeptide repeat-like domain (PF09976; HMM-score: 21)
  and 12 more
  no clan defined SlyX; SlyX (PF04102; HMM-score: 15.4)
  TMP_2; Prophage tail length tape measure protein (PF06791; HMM-score: 15)
  ETRAMP; Malarial early transcribed membrane protein (ETRAMP) (PF09716; HMM-score: 14.7)
  DUF4307; Domain of unknown function (DUF4307) (PF14155; HMM-score: 12.9)
  FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 12.4)
  no clan defined MRPL52; Mitoribosomal protein mL52 (PF18699; HMM-score: 11.7)
  LapA_dom; Lipopolysaccharide assembly protein A domain (PF06305; HMM-score: 11.4)
  SP24; Putative virion membrane protein of plant and insect virus (PF16504; HMM-score: 10.8)
  YebO; YebO-like protein (PF13974; HMM-score: 8.1)
  Histone_HNS; H-NS histone family (PF00816; HMM-score: 7.4)
  Ax_dynein_light; Axonemal dynein light chain (PF10211; HMM-score: 6.3)
  DUF6080; Family of unknown function (DUF6080) (PF19558; HMM-score: 5.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.0001
  • Cytoplasmic Membrane Score: 0.2147
  • Cell wall & surface Score: 0.0677
  • Extracellular Score: 0.7174
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.149429
  • TAT(Tat/SPI): 0.002244
  • LIPO(Sec/SPII): 0.006393
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI:
• RefSeq: ARD37870 NCBI
• UniProt:

⊟Protein sequence

• MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQAKIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKESSKAIVDFHLQKGLAYDVKDSDDKFKDKATLETNVKEINKQIDFIKKVDKTFKQENLEETLKSLNDIVDKYQKQIEILKKQEEEKAAKKAKESSSQSNSSGRASNESYNGSSNSNVDYSSSEQTNRYSNNYGGQDYSSSGNSSTNGGSSEQYSSSNSNSGVNNGYYTKYKNIGADGYVRDTYHNESNGDVFDENGNYLGNTGGGIAEPPQR

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications