PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 02-APR-2021

⊟Summary

• organism: Streptococcus pneumoniae Hu15
• locus tag: SPNHU15_RS07725 [old locus tag: SPNHU15_01628 ]
• pan locus tag^?: PNEUPAN002986000
• symbol: SPNHU15_RS07725
• pan gene symbol^?: rpsO_1
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU15_RS07725 [old locus tag: SPNHU15_01628 ]
• symbol: SPNHU15_RS07725
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 1535140..1535616
• length: 477
• essential: unknown

⊟Accession numbers

• Location: NZ_CP020551 (1535140..1535616) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1429 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  
  ATGGCAAAAGAACCGTGGCAAGAAGATATTTATGATCAAGAAGAATCAAGAGCAGGGCGT
  CGGCATCGAAACCACGGAGGGGCTGATAGGATGGCTAATCGTATTTTGACGATCCTAGCT
  AGTATTTTCTTTGTAATTGTGGTGGTGATGGTCATCGTTCTCATCTATCTATCATCGGGG
  GGGAGCAATCGCACAGCAGCCTTAAAAGACTTTCATGATTCTGATGCAAGTGTAGTACAA
  ATCTCATCTTCAAGCAGTTCTCAGCCTGAGCAGAGTTCAGAGCCAGAATCTACTTCTAGT
  AGTTCAGAAGAAGCTGCTAATCCTGAAGGAACGATTAAAGTTCTCGCAGGAGAAGGGGAA
  GCAGCTATTGCCGCTCGTGCAGGAATCTCCATTGCTCAGTTAGAGGCCTTGAATCCTGGG
  CACATGGCTACAGGATCTTGGTTTGCTAATCCAGGTGATGTTATAAAAATAAAATAG
  60
  120
  180
  240
  300
  360
  420
  477
  

⊟Protein

⊟General

• locus tag: SPNHU15_RS07725 [old locus tag: SPNHU15_01628 ]
• symbol: SPNHU15_RS07725
• description: hypothetical protein
• length: 158
• theoretical pI: 4.78786
• theoretical MW: 16797.6
• GRAVY: -0.189873

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Pathogenesis type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus protein PrgH/EprH (TIGR02554; HMM-score: 14.9)
  variant surface antigen, rifin family (TIGR01477; HMM-score: 13.1)
  and 1 more
  Metabolism Transport and binding proteins Other Niemann-Pick C type protein family (TIGR00917; HMM-score: 10.7)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  no clan defined SecG; Preprotein translocase SecG subunit (PF03840; HMM-score: 16.7)
  DUF1673; Protein of unknown function (DUF1673) (PF07895; HMM-score: 16)
  MSP1a; Major surface protein 1a (MSP1a) (PF11670; HMM-score: 15.3)
  VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 14.8)
  no clan defined DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 14.7)
  LysM (CL0187) LysM; LysM domain (PF01476; HMM-score: 14.3)
  no clan defined ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 14.3)
  Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 13.9)
  and 7 more
  MRAP; Melanocortin-2 receptor accessory protein family (PF15183; HMM-score: 12.6)
  Orf78; Orf78 (ac78) (PF06024; HMM-score: 12)
  OB (CL0021) tRNA_anti-like; tRNA_anti-like (PF12869; HMM-score: 12)
  no clan defined Shisa; Wnt and FGF inhibitory regulator (PF13908; HMM-score: 11.9)
  ASFV_J13L; African swine fever virus J13L protein (PF05568; HMM-score: 11.7)
  SCAI; Protein SCAI (PF12070; HMM-score: 11.3)
  4HB_MCP (CL0457) TarH; Tar ligand binding domain homologue (PF02203; HMM-score: 11.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helix: 1
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001714
  • TAT(Tat/SPI): 0.000249
  • LIPO(Sec/SPII): 0.00105
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI:
• RefSeq: WP_001040912 NCBI
• UniProt:

⊟Protein sequence

• MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFFVIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSSEEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1429 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications