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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-APR-2017

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu17
  • locus tag: SPNHU17_01050 [new locus tag: SPNHU17_RS10965 ]
  • pan locus tag?: PNEUPAN002024000
  • symbol: SPNHU17_01050
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU17_01050 [new locus tag: SPNHU17_RS10965 ]
  • symbol: SPNHU17_01050
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 967662..968072
  • length: 411
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP020549 (967662..968072) NCBI
  • BioCyc: see SPNHU17_RS10965
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    TTGTACTCTATCAAAAACTCTACGATATTCTCATGTCGCTTAGAAAGTAATAATGGATCT
    GATGCGGACTTTGATAAGGTGGATGCATTATTAGATCAACTTTCTGCTAATAGTAAAGAC
    AAAACAGCTTTACTTGAATCGACAAAAGCTATTCTAGTTTTGAATCATCAAATCCAGTCA
    AAAGCTAGCGCAAGTGAAGAAACAAGTCCAGCAAGAAATGCTGAAGCAAATGGTGATAAC
    ACCAGTGCTGAGAACCAACCAAACGCAACTGCAGAATCTAACATTGAAACTGCTAGCGAC
    GAAAACAAACCAAGCAATACAAGAGATTCTAAACCTGCTGAATCAACTTCAGAAAATAAA
    ACAACAGAATCTTCTACAACTACTGGAAATCAAGAAAAACCAGTAGAATAA
    60
    120
    180
    240
    300
    360
    411

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPNHU17_01050 [new locus tag: SPNHU17_RS10965 ]
  • symbol: SPNHU17_01050
  • description: hypothetical protein
  • length: 136
  • theoretical pI: 4.23096
  • theoretical MW: 14528.3
  • GRAVY: -1.03529

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin cobaltochelatase, CobT subunit (TIGR01651; EC 6.6.1.2; HMM-score: 7.2)
    Metabolism Transport and binding proteins Anions anion exchange protein (TIGR00834; HMM-score: 6.5)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    PTase-anion_tr (CL0340) Band_3_cyto; Band 3 cytoplasmic domain (PF07565; HMM-score: 12.1)
    no clan defined CobT; Cobalamin biosynthesis protein CobT (PF06213; HMM-score: 11.7)
    GAGA_bind; GAGA binding protein-like family (PF06217; HMM-score: 11.2)
    and 3 more
    Eapp_C; E2F-associated phosphoprotein (PF10238; HMM-score: 8)
    RR_TM4-6; Ryanodine Receptor TM 4-6 (PF06459; HMM-score: 7.6)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 5.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.039
    • Cytoplasmic Membrane Score: 0.0091
    • Cell wall & surface Score: 0.0032
    • Extracellular Score: 0.9488
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008811
    • TAT(Tat/SPI): 0.007091
    • LIPO(Sec/SPII): 0.001448
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ARD34640 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MYSIKNSTIFSCRLESNNGSDADFDKVDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]