PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 25-AUG-2021

⊟Summary

• organism: Streptococcus pneumoniae Hu17
• locus tag: SPNHU17_RS07635 [old locus tag: SPNHU17_01633 ]
• pan locus tag^?: PNEUPAN002984000
• symbol: SPNHU17_RS07635
• pan gene symbol^?: phnA
• synonym:
• product: alkylphosphonate utilization protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SPNHU17_RS07635 [old locus tag: SPNHU17_01633 ]
• symbol: SPNHU17_RS07635
• product: alkylphosphonate utilization protein
• replicon: chromosome
• strand: -
• coordinates: 1514329..1514667
• length: 339
• essential: unknown

⊟Accession numbers

• Location: NZ_CP020549 (1514329..1514667) NCBI
• BioCyc: SPNHU17_RS07635 BioCyc
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1427 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  
  ATGAACAATTTACCAAATTGTCCAAAATGTAACTCAGAGTATGTCTACGAAGACGGTGCC
  CTACTGGTTTGCCCAGAGTGTGCTCATGAGTGGAATCCTGCTGAAGTTGCAGAAGTAGAA
  GAAGGTCTTGTCGCTATCGATGCCAACGGAAATAAATTGACTGATGGTGATACAGTAACT
  CTCATCAAGGACTTGAAAGTAAAAGGTGCGCCAAAAGATTTGAAACAAGGGACGCGCGTG
  AAAAATATCCGCATCGTAGAAGGCGATCACAATATCGACTGTAAGATTGATGGTTTTGGT
  GCCATGAAACTTAAATCAGAGTTTGTGAGGAAGATTTAA
  60
  120
  180
  240
  300
  339
  

⊟Protein

⊟General

• locus tag: SPNHU17_RS07635 [old locus tag: SPNHU17_01633 ]
• symbol: SPNHU17_RS07635
• description: alkylphosphonate utilization protein
• length: 112
• theoretical pI: 4.9408
• theoretical MW: 12314
• GRAVY: -0.390179

⊟Function

• TIGRFAM:
  Unknown function General putative alkylphosphonate utilization operon protein PhnA (TIGR00686; HMM-score: 166.7)
  and 3 more
  flagellar operon protein TIGR03826 (TIGR03826; HMM-score: 17.2)
  Genetic information processing Transcription Transcription factors transcription factor S (TIGR01384; HMM-score: 15.6)
  Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 8.4)
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  SH3 (CL0010) YjdM; PhnA domain (PF03831; HMM-score: 111.1)
  and 16 more
  Zn_Beta_Ribbon (CL0167) YjdM_Zn_Ribbon; PhnA Zinc-Ribbon (PF08274; HMM-score: 59.7)
  TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 17.3)
  no clan defined FtrD-like; Membrane iron-sulfur containing protein FtrD-like (PF10080; HMM-score: 17.1)
  Zn_Beta_Ribbon (CL0167) A2L_zn_ribbon; A2L zinc ribbon domain (PF08792; HMM-score: 16.2)
  zf-RRN7; Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 (PF11781; HMM-score: 14.9)
  zf-TFIIB; Transcription factor zinc-finger (PF13453; HMM-score: 14.8)
  zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 13.1)
  zinc-ribbons_6; zinc-ribbons (PF07191; HMM-score: 12.9)
  OrfB_Zn_ribbon; Putative transposase DNA-binding domain (PF07282; HMM-score: 12.9)
  HeH (CL0306) PADR1; PADR1 (NUC008) domain (PF08063; HMM-score: 12.6)
  Zn_Beta_Ribbon (CL0167) UPF0547; Uncharacterised protein family UPF0547 (PF10571; HMM-score: 12.5)
  TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 11.7)
  no clan defined FYDLN_acid; Protein of unknown function (FYDLN_acid) (PF09538; HMM-score: 11.3)
  Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 11)
  Zn_Tnp_IS1; InsA N-terminal domain (PF03811; HMM-score: 10.4)
  Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 9.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.013035
  • TAT(Tat/SPI): 0.000275
  • LIPO(Sec/SPII): 0.002127
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_001061594 NCBI
• UniProt:

⊟Protein sequence

• MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLVAIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAMKLKSEFVRKI

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Expression data

• PneumoExpress for strain D39V: SPV_1427 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications