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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 07-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu17
  • locus tag: SPNHU17_RS11050 [old locus tag: SPNHU17_01806 ]
  • pan locus tag?: PNEUPAN003243000
  • symbol: SPNHU17_RS11050
  • pan gene symbol?: —
  • synonym:
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU17_RS11050 [old locus tag: SPNHU17_01806 ]
  • symbol: SPNHU17_RS11050
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin
  • replicon: chromosome
  • strand: -
  • coordinates: <1685318..1686667
  • length: 1350
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP020549 <1685318..1686667 NCBI
  • BioCyc: SPNHU17_RS11050 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATATTTTTTAGACGTCAGAAGGGTGAATATAGAGAAACAGACCGAGTAACTCGGTTCAAA
    TTAATCAAATCAGGGAAGCATTGGCTACGGGCCTCGACTTCTCTTTTTGGCTTGTTTAAG
    GTCTTGCGAGGTGGTGTTGATACTACTCAGGTCATGACCGAAACGGTAGAAGATAAAGTA
    AGTCATTCAATTACTGGGCTTGATATCCTCAAGGGGATAGTTGCTGCGGGAACTGTCATA
    AGTGGAACCGTTGCAACTCAAACGAAGGTATTTACAAATGAGTCGGCAGTACTTGAAAAA
    ACTGTAGAGAAAACGGATGCTTTGGCAACAAATGGTACAGTAGTTCTAGGTACGATATCT
    ACAAGTAATTCAGCGAGTTCAACTAGTTTGTCAGCTTCAGAGTCGGCAAGTACATCTGCA
    TCTGAGTCAGCCTCAACCAGCGCTTCGACCTCAGCGAGTACAAGTGCATCAGAATCAGCA
    AGTACATCGGCTTCGACAAGTATCTCTGCATCATCTACTGTGGTAGGATCACAAACAGCT
    GCCGCTACAGAAGCAACTGCTAAGAAGGTCGAAGAAGATCGTAAGAAACCAGCTAGTGAT
    TATGCAGCATCAGTTACAAATGTCAATCTCCAATCTTATGCTAAGCGACGCAAGCGTTCA
    GTGGATTCCATCGAGCAATTGCTGGCTTCTATAAAAGCTGCTGTTTTTTCTGGCAATACG
    ATTGTAAATGGCGCCCCTGTAATTAATGCAAGTCTAAACATTGCTAAAAGTGAGACAAAA
    GTTTATACAGGTAAAGGTGTAGATTCGGTATATAATGTTCCAATTTACTATCAATTGAAA
    GTGACAAATGATGGTTCAAAATTGACCTTTACCTATACAGTCACCTATGTAAATCCTAAC
    ACAAGGGCTCTTGAAAATCTTTCAAGAATGTCTTATAGATATTCTATCTATAATGCAGGT
    ACTTCAACACAAACAATGTTAACCCTTGGCAGAGGTCTTGGTAAACCTTCAGTTGTAAAG
    AACTACATTACTGACAAAGATGGTAGACAGGTTCGATACTATAATACATCTACAATGACG
    AAGCGGGGTAGTGGGTATACTTGGGCAAATGGTGCCCAAATGAATGGTTGGTATGCTAAG
    AAAGAATATGGATTAACATCATCTTGGACTGTACCAATTACTGGAACGGATACATCCTTT
    ACATTTACCCCTTACGCTGCTAAAACAGATAGAATTGGAATTAACTACTTCAAGGGTAGA
    GGAAAGGTAGTTGAATCTAGCACGACCAGTCAGTCACTTTCACAGTCTAAGTCACTCTCA
    GTAAGTGCTAGTCAAAGCGCCTCAGCTTCA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1350

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU17_RS11050 [old locus tag: SPNHU17_01806 ]
  • symbol: SPNHU17_RS11050
  • description: accessory Sec-dependent serine-rich glycoprotein adhesin
  • length: 450
  • theoretical pI: 10.2568
  • theoretical MW: 47914.1
  • GRAVY: -0.329333

⊟Function[edit | edit source]

  • TIGRFAM:
    serine-rich repeat adhesion glycoprotein (TIGR04224; HMM-score: 67.3)
    and 2 more
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 29.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair UV excision repair protein Rad23 (TIGR00601; HMM-score: 4.9)
  • TheSEED:
  • PFAM:
    no clan defined KxYKxGKxW_sig; KxYKxGKxW signal peptide (PF19258; HMM-score: 38.4)
    and 4 more
    Tox-SGS; Salivary glad secreted protein domain toxin (PF15651; HMM-score: 12.9)
    SOBP; Sine oculis-binding protein (PF15279; HMM-score: 10.3)
    Med3; Mediator complex subunit 3 fungal (PF11593; HMM-score: 9.8)
    Macoilin; Macoilin family (PF09726; HMM-score: 7.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.2
    • Extracellular Score: 0.78
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.1273
    • Extracellular Score: 0.8723
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.033294
    • TAT(Tat/SPI): 0.007117
    • LIPO(Sec/SPII): 0.002847
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_257788419 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVLRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVISGTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPVINASLNIAKSETKVYTGKGVDSVYNVPIYYQLKVTNDGSKLTFTYTVTYVNPNTRALENLSRMSYRYSIYNAGTSTQTMLTLGRGLGKPSVVKNYITDKDGRQVRYYNTSTMTKRGSGYTWANGAQMNGWYAKKEYGLTSSWTVPITGTDTSFTFTPYAAKTDRIGINYFKGRGKVVESSTTSQSLSQSKSLSVSASQSASAS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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