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serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_06020 [new locus tag: SPNINV200_RS03215 ]
  • pan locus tag?: PNEUPAN001596000
  • symbol: SPNINV200_06020
  • pan gene symbol?: rsuA-2
  • synonym:
  • product: putative ribosomal small subunit pseudouridine synthase A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_06020 [new locus tag: SPNINV200_RS03215 ]
  • symbol: SPNINV200_06020
  • product: putative ribosomal small subunit pseudouridine synthase A
  • replicon: chromosome
  • strand: -
  • coordinates: 617426..618151
  • length: 726
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGCGTTTAGATAATTTATTAGCCCAAGAAAAAGTTAGCCGAAAGGCCATGAAGCAAGCA
    CTCCTCAGAGGGGAAATTCTAGTCGATGGTTGCCCAGCCCGCTCCCTAGCTCAAAATATC
    GATACAGGACTACAAGAACTCCTTTTTCAGGATCGAATCATTCAAGGCTATGAACACACC
    TATCTTATGCTTCATAAACCTGCTGGTGTCGTTACAGCCAACAAAGACAAGGAACTTCCG
    ACCGTCATGGACCTGCTTCCATCTGACATCCAGTCTGACAAGCTCTATGCCGTCGGCCGA
    CTGGACCGAGATACAACAGGACTCCTTCTCTTGACCGATAACGGTCCCTTGGGCTTCCAA
    CTCCTCCATCCCCAATATCATGTCGATAAGACTTATCAAGTTGAGGTTAATGGACTTCTA
    ACACCTGACCATATCCAAGCCTTTCAAAAGGGAATTGTCTTTTTAGATGGTACTGTCTGT
    AAACCCGCAAAACTAGAGATTCTATCTGCAAGTCCTTCCCTCAGTCAAGCCTCTATCACC
    ATTTCAGAAGGAAAATTTCATCAAATCAAGAAAATGTTCCTCTCGGTTGGTGTTAAGGTA
    ACTAGCCTCAAGAGAATCCAATTTGGGGACTTCACATTGAACCCAGATTTAGCAGAAGGT
    AACTACCGCCCTTTGAACCAAAAAGAGTTACAAATCATTAAAAACTATTTAGAGATGAGT
    CGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    726

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_06020 [new locus tag: SPNINV200_RS03215 ]
  • symbol: SPNINV200_06020
  • description: putative ribosomal small subunit pseudouridine synthase A
  • length: 241
  • theoretical pI: 8.21634
  • theoretical MW: 27000.1
  • GRAVY: -0.198755

⊟Function[edit | edit source]

  • reaction:
    EC 4.2.1.70?  ExPASy
    Pseudouridylate synthase Uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O
  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 146.7)
    and 2 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 33.4)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 22.8)
  • TheSEED  :
    • Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70)
  • PFAM:
    PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 65.1)
    and 1 more
    S4 (CL0492) S4; S4 domain (PF01479; HMM-score: 22.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9955
    • Cytoplasmic Membrane Score: 0.0015
    • Cell wall & surface Score: 0.0018
    • Extracellular Score: 0.0012
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011097
    • TAT(Tat/SPI): 0.004423
    • LIPO(Sec/SPII): 0.005112
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW34235 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGLQELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLDRDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVCKPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLAEGNYRPLNQKELQIIKNYLEMSR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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