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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_10710 [new locus tag: SPNINV200_RS05735 ]
  • pan locus tag?: PNEUPAN002299000
  • symbol: zmpD
  • pan gene symbol?: zmpD
  • synonym:
  • product: IgA-protease ZmpB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_10710 [new locus tag: SPNINV200_RS05735 ]
  • symbol: zmpD
  • product: IgA-protease ZmpB
  • replicon: chromosome
  • strand: -
  • coordinates: 1086907..1091976
  • length: 5070
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312029 (1086907..1091976) NCBI
  • BioCyc: see SPNINV200_RS05735
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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    121
    181
    241
    301
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    481
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    1021
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    1501
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    5041
    TTGATTGTAGGGGCGACAGGTTTAGTTACACTATCAACTGCTTCAGCACTTAATTTGAAT
    GCTAACATCCATGAGTCTGGACGTGATGGTGTGTTGCAAATTTCTGGTTACAGATATGTT
    GGTTACTTGGAGCTTGATGATAAAACTGTTTCGTCGGTTTCTCCAGCATCAACTGTTTCG
    CCAGTTGAGCAACCCAAAGTTGTAACAGAGAAAGGGGAACCGGAGGTTCAACCAGCCTTA
    CCCGAAGCTGTTGTGACTGACAAAGGCGAACCGGAAGTACAACCGACATTACCAGAAGCT
    GTTGTGACTGACAAAGGCGAACCAGAAGTTCATGAGAAGCCTGACTATACGCAACCAATA
    GGTGCAAACCTTGTTGAGCCTGAAGTTCATGAGAAACTAGCATACACTGAATCAGTAGGT
    ACAACAGGAATGGATGAAAACGGAAACTTGATTGAACCACCTGTTAGCGATATTCCAGAA
    TACACTGAATCAGTAGGTACAACAGGAGTGGACGAAAATGGAAACTTGATTGAACCACCT
    GTTAGCGATATTCCAGAATACACTGAATCAGTAGGTACAACAGGAGTGGACGAAAACGGA
    AACTTGATTGAACCACCTGTTAACGACATTCCAGAGTATACTGAACCAATATCTACAGTT
    TCAGAAGTTGCATCAGAAAGAGAAGAGTTGCCTTCTTTACATACCGATATTCGTACAGAG
    ACTATTCCTAAAACCACTATAGAAGAATCTGATCCTAGCAAATTTATAGGCGATGATTCT
    GTTAAAGAAGTTGGTGAGGATGGCGAACGTCAAATTGTTACTAGCTATGAAGAGTTACAT
    GGCAAAAAAATTAGTGAACCAGTTGAAACGGTAACAATTTTGAAAGAAATGAAACCTAAA
    ATTCTTGTAAAAGGTACAAAAGAAAATCCAAAAGAAAAAACAGTTCCCGTTTTGACCTTG
    ACCAAAGTAACAGAAGATGCTATGAATCGTTCTGCCAACTTAAATTATGAGCTTGATAAT
    AAAGATAATGCTGAAATATCAAGTATTATAGCTGAAATTAAAGATGGTGATACAGTAGTT
    AAAAAGGTTGATTTATCTAAAGAAAAATTAACTGACGCTGTACAAAATTTGGATTTGTTT
    AAAGATTATAAGATTGCAACAACAATGATTTATGATCGTGGTCAAGGTTCTGAAACGTCT
    AAACTGGATGAAAAAACTTTGCGTTTGGAGTTGAAAAAGGTCGAAATTAAAAATATTTCA
    TCTACTAATTTAGTGAAGGTAAATGATGATGGTACTGAAATACCTAGTGATTTCATGAGC
    GAAAAACCTTCTGATGAAGATGTGAAGAAAATGTACTTAAAAATCACTAGTCGTGATAAT
    AAAGTAACTCGTTTAGCAGTTGATAAGATTGAGTTAGTAACTGAAAAAGAAAAAGAACTT
    TATAAAATTACAGCAAGCGCTCAAGATTTAATTCAACATGTCGATCCATCTAAGACTAGA
    AATGAATACATTCATTACATTGAAAAACCAGTTCCAAAAGTCAATAATGTATATTACAAT
    TTCAATGAACTTGTGAGAGATATGCAAGAACATCCAAATGACGAGTTTAAATTGGGTGCT
    GACCTTAATGCCACAAATGTATCAGCATTTGGTAAATCATATGTTACGAAAGATTTCAAA
    GGTAAGCTCTTGAGTGATGGTGATAATCACTATACCATTCATAACTTGTCACGTCCGTTA
    TTTGGCAATGTTATTGGTGGAACGATTAAGAATATTAATCTTGGTAATGTTGACATAAAT
    ATGCCATGGGCGAACCAAGTTGCAGCTGTAGCGAATATTATTAAAGGTGGAACTACCATT
    GAAAATGTTAAGGTTAAAGGTAATATAGTAGGTAAAGATTGGGTATCTGGATTTATTGAT
    AAGATTGATAACCAAGGTACACTCAGAAATGTGGCCTTTATCGGTAACGTAACTTCTGTC
    GGCGATGGTGGACAATTCTTGACTGGTATCGTTGGTGAGAACTGGAAAGGACTCGTCGAA
    CGCGCGTATGTTAACGCAAATCTTATTGGCAAGAAAGCCAAGGCTGCGGGCATTGCTTAT
    TGGACACAAAATGAAGGAAATAACAATACTGTTCGTCAGGAAGGAGCAATCAAAAAATCT
    ATTGCTAAGGGAACAATTCAAGTAACTGAGGCGATTGAAAGTGGTGGTGTTGTAGGAAGC
    ATGAAGCACCACGGTTCTGTCGAAGATTCAGTTTCCATGATGAAGGTACCTAATGGTGAA
    ATTTTCTATGGTTCTAGTGATATTGATTATGATGATGGCTACTGGACAGGAGATAATGTA
    AGACGAAATTATGTTGTAATAGGTGTTAGTGATGGGCATTCTAGCTACCAGCGTTCAAAA
    GATAAAAATCGTATCAGACCTATTTCTGAGGAAGAGGCAAAATCTAAAATTGAAGCTACA
    GGAATTACCGCAGATAAATACGAAATCAATGAACCTGTGGTCAATCGCTTAAATCGTTTA
    ACCAGAAGAGAAGATGAATATAAGTCAACCCAAGACTATAAAGTAGATCGAGATCTGGCT
    TATCGTAATATTGAGAAACTGCAACCATTTTATAACAAAGAATGGATTGTCAATCAAGGT
    AACAAACTTGCAGAAGATTCAAACTTAGCTAAGAAAGAAGTCCTTTCTGTTACGGGTATG
    AAGGATGGTCAATTCGTGACCGATTTATCAGATATTGATCATGTGATGATTCACTATGCA
    GATAAGACTAAAGAAATCAAAGCTGTTCATCAAAAAGAGTCTAAAGTAGCGCAAGTTCGT
    GAGTATAGTATCGATGGATTAGATGACATTGTTTATACACCAAACATGGTTGATAAAAAT
    CGTGATCAATTGATTAAAGACATTAAAGATAGGTTAGCAACTGTTGAATTAATTTCTCCC
    GAAGTCCGTGCTTTGATGGATAAACGAGATACATCTAGAGATCCTAATGCTAATTCGGAT
    GAGCGTAAGAATGGTTATATCCGAGACCTTTATTTCGAAGAAAGTTTTTCTGAAACGAAA
    GCTAATCTTGATAAATTGGTCAAATCTTTGATTGAAAATGCTGACCATCAATTAAATAGT
    GACGAAGCAGCTATGAAAGCACTTGTTAAGAAGGTGGATGAAAATAAAGCTAAAATCGTG
    ATGGCTCTTACTTACCTTAATCGTTACTATGATATCAAGTATGGGGATATGACTATCAAA
    AACTTGATGATGTTTAAACCTGATTTCTATGGTAAGTCAGTTGACCTTCTTGACTTCTTG
    ATTCGAATTGGATCAAGTGAGCGAAATATCAAGGGTGACAGAACTTTGGATGCTTATCGT
    GATATGATTGGTGGAACTATTGGTAAGTCTGAATTACATGGCTTCTTAGATTACAACATG
    CGTCTCTTCACTAACGATACTGATTTAAATGATTGGTTTATCCATGCGGCTAAGAACGTA
    TACATTGTGGAGCCTAAAACAACGAACCCAGATTTTGTTAATAAACGACATCGTGCATTT
    GATGGTTTGAATAATGGTGTTCATAATCGTATGATCCTACCTCTATTAACTCTTAAGAAT
    GCACATATGTTCTTGATTTCGACTTACAATACAATGGCTTATAGCTCTTTTGAAAAATAT
    GGTAAGTATACAGAAGCTGAACGAGAAGCATTTAAAGATAAAATTAAAGAAGTTGCTCAC
    GCACAACAAACTTATCTTGACTTCTGGTCGCGTTTAGCATTGCCAAGCGTACGTGACCAA
    TTACTCAAGAGTCAAAATAGGGTTCCAACACCTGTTTGGGATAACCAAAACTATCATAAC
    GTCGAAGGTGTAAATCGTATGGGTTATGATAAGAATAATAAACCAATTGCACCTATTCGT
    GAATTATATGGACCTACTTGGCGTTATCATACTACAAATTGGTACATGGGAGCTATGGCA
    TCTATTTTCCAAGATCCCAATAATAATGACCAAGTTTATTTCATGGGAACAAATATGATT
    AGTCCGTTTGGTATTTCAGCCTTTACTCACGAAACAACACACGTAAACGATAGAATGCTT
    TACTTCGGTGGGCATAGACACCGTCAAGGTACAGACGTTGAAGCCTATGCGCAAGGTATG
    TTGCAGACACCTGATAAATCTGGTAACGGTGAATATGGTGCTCTTGGTCTTAACATGGCT
    TATCATCGTGAAAATGACGGTGACCAATGGTATAATTATGATCCAGATAAATTGAAAACT
    CGTGAAGATATCGACCGTTATATGAGAAATTATAATGATGCTCTTATGATGTTAGACCAT
    CTTGAGGCTGATGCTGTTATCCCTAAATTACATGGTAATATTAGTCGATGGTTCAAGAAA
    ATGGATAGACAATATCGCAAAAATGGAGAGCTACATCAATTTGATAAAGTTCGTGAATTA
    ACTGAAGATGAGAAGAAGAAAATTGTTATCAACAACATTGATGATTTAGTCAACAATAAT
    TTGATGACAAAACATGGCGCTCCTAGTGACAGAACATATAATCCAGAAGATTTTGATAGT
    GCTTACGTAAATATTAATATGATGACCGGTATCTATGGTGGTAATACTAGCCAAGGAGCA
    CCTGGAGCTGCATCATTCAAGCATAATACTTTCCGTATGTGGGGCTATTTTGGTTATGAA
    AATGGATTCATTAGTTATGCATCTAGCAAATATCAAGGCGAAGCTGACAAAACCAATAAA
    AAATTATTGGGTGATGATTTCATTATCAAGAAAGTATCTAAGGATAAATTCAATAATCTT
    GAAGAGTGGAAGAAACAATACTTCAAAGATGTTAAGTCAAAAGCAGAAAAAGGATTTACT
    GCTATTGAAATTGATGGTCGTCAAATTACAAATTATGCTCAGTTGAAAACTTTATTTGCT
    GAAGCTGTTCAAAAAGATATTGATGGTATGTCAGATCCGAAAATTAAAGATCATTTCAAA
    AATACAGTAGACTTGAAATCCAAAGTATTCAAAGCCCTTCTTAAAAACACAGACGGTTTC
    TTTAATAAACTGTTTAAAGAAGACATTTAA
    60
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_10710 [new locus tag: SPNINV200_RS05735 ]
  • symbol: ZmpD
  • description: IgA-protease ZmpB
  • length: 1689
  • theoretical pI: 5.26394
  • theoretical MW: 190747
  • GRAVY: -0.662167

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Zinc metalloprotease zmpB precursor (EC 3.4.24.-)
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 826.7)
    and 2 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 254.1)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 35.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.2
    • Extracellular Score: 0.78
    • Internal Helices: 0
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0009
    • Cytoplasmic Membrane Score: 0.0111
    • Cell wall & surface Score: 0.84
    • Extracellular Score: 0.148
  • SignalP: Signal peptide SP(Sec/SPI) length 21 aa
    • SP(Sec/SPI): 0.470685
    • TAT(Tat/SPI): 0.008094
    • LIPO(Sec/SPII): 0.050693
    • Cleavage Site: CS pos: 21-22. LNA-NI. Pr: 0.1846
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW34704 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDKTVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTESVGTTGMDENGNLIEPPVSDIPEYTESVGTTGVDENGNLIEPPVSDIPEYTESVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVTSYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDVKKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHYIEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLLSDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIENVKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVVGSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSYQRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKDRLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVKSLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQLLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGAMASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDALMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINNIDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINMMTGIYGGNTSQGAPGAASFKHNTFRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYFKDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLKSKVFKALLKNTDGFFNKLFKEDI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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