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JJA
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MDRSPN001
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NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC03020 [new locus tag: SPNOXC_RS01665 ]
  • pan locus tag?: PNEUPAN001032000
  • symbol: manL
  • pan gene symbol?: manL
  • synonym: manX
  • product: putative mannose-specific phosphotransferase system (PTS), IIAB component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC03020 [new locus tag: SPNOXC_RS01665 ]
  • symbol: manL
  • product: putative mannose-specific phosphotransferase system (PTS), IIAB component
  • replicon: chromosome
  • strand: -
  • coordinates: 294276..295265
  • length: 990
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGTATCGGAATCATTATTGCGAGCCACGGCGAATTTGCTGCGGGTATTCATCAGTCA
    GGATCTATGATCTTTGGTGAACAAGAAAAGGTTCAAGTTGTGACCTTTATGCCAAATGAA
    GGTCCTGATGATCTATACGCTAAGTTTAATAACGCTGTTGCTGCATTTGACGCAGAAGAT
    GAGGTTCTAGTTTTGGCTGACCTTTGGAGTGGTTCTCCATTTAACCAAGCTAGTCGCGTG
    ATGGGAGAAAATCCTGAGCGTAAGTTTGCCATCATCACAGGACTTAACTTACCGATGTTG
    ATTCAAGCCTACACAGAGCGCCTCATGGACGCTGCTGCAGGTGTAGAAAAAGTCGTTGCT
    AATATCATTAAAGAAGCCAAAGATGGCATCAAAGCTCTTCCAGAAGAGCTAAATCCAGTT
    GAAGAAGTTGCAAGCGCTGCAGCTGCTCCAGTTGCCCAAGCTGCTATCCCAGAAGGAACT
    GTTATCGGAGACGGTAAATTGAAAATCAATCTTGCCCGTCTTGACACACGTCTACTTCAC
    GGTCAGGTTGCAACTGCTTGGACTCCAGATTCAAAAGCAAATCGTATCATCGTTGCTTCA
    GATAACGTGGCTAAAGACGACCTTCGTAAAGAATTGATTAAACAAGCAGCTCCAGGTAAT
    GTCAAGGCTAACGTGGTTCCAATTCAAAAACTGATTGATATTTCAAAAGACCCACGTTTT
    GGAGAAACACATGCCCTTATCTTGTTTGAAACACCTCAAGATGCCCTTCGTGCCATCGAA
    GGCGGCGTGCCAATCAAGACTCTTAACGTTGGTTCTATGGCTCACTCAACAGGTAAAACA
    TTGGTCAATACCGTTTTGTCTATGGACAAAGAAGATGTTGCTACATTTGAAAAAATGCGT
    GACTTGGGTGTTGAATTTGATGTCCGTAAAGTACCAAATGATTCTAAAAAAGATTTGTTT
    GACTTGATTAACAAAGCCAATGTCAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    990

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC03020 [new locus tag: SPNOXC_RS01665 ]
  • symbol: ManL
  • description: putative mannose-specific phosphotransferase system (PTS), IIAB component
  • length: 329
  • theoretical pI: 4.91492
  • theoretical MW: 35427.4
  • GRAVY: -0.0644377

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIB component (TIGR00854; EC 2.7.1.69; HMM-score: 152.7)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIB component (TIGR00854; EC 2.7.1.69; HMM-score: 152.7)
    and 2 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 97.5)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIA component (TIGR00824; EC 2.7.1.69; HMM-score: 97.5)
  • TheSEED  :
    • PTS system, mannose-specific IIA component (EC 2.7.1.69)
    • PTS system, mannose-specific IIB component (EC 2.7.1.69)
    Carbohydrates Monosaccharides Mannose Metabolism  PTS system, mannose-specific IIB component (EC 2.7.1.69)
  • ⊞PFAM:
    no clan defined PTSIIB_sorb; PTS system sorbose subfamily IIB component (PF03830; HMM-score: 166.4)
    and 2 more
    EDD (CL0245) EIIA-man; PTS system fructose IIA component (PF03610; HMM-score: 123.4)
    no clan defined Pro_Al_protease; Alpha-lytic protease prodomain (PF02983; HMM-score: 11.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014909
    • TAT(Tat/SPI): 0.00058
    • LIPO(Sec/SPII): 0.003977
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW31962 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDDLYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQAYTERLMDAAAGVEKVVANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGTVIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAPGNVKANVVPIQKLIDISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHSTGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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