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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
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ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
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G54
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HU-OH
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Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
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SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC09020 [new locus tag: SPNOXC_RS04885 ]
  • pan locus tag?: PNEUPAN002030000
  • symbol: lmb
  • pan gene symbol?: lmb
  • synonym: adcAII
  • product: laminin binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC09020 [new locus tag: SPNOXC_RS04885 ]
  • symbol: lmb
  • product: laminin binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 909215..910132
  • length: 918
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAAGAAACAAAATTTATTTTTAGTCCTGTTAAGTGTCTTTCTTTTGTGCTTGGGGGCT
    TGTGGTCAAAAGGAAAGTCAGGCAGGAAAGGGGATGAAAATTGTGACCAGTTTTTATCCT
    ATCTACGCTATGGTTAAGGAAGTATCTGGTGACTTGAATGATGTTCGGATGATTCAGTCA
    AGTAGTGGTATTCACTCCTTTGAACCTTCGGCAAATGATATCGCAGCCATCTATGATTCA
    GATGTCTTTGTTTACCATTCTCATACACTCGAATCTTGGGCAGGAAGTCTGGATCCAAAT
    CTAAAAAAATCCAAAGTGAAGGTCTTAGAGGCTTCTGAGGGAATGACCTTGGAACGTGTC
    CCTGGACTAGAGGATGTGGAAGCAGGGGATGGAGTTGATGAAAAAACGCTCTATGACCCT
    CACACATGGCTAGATCCTGAAAAAGCTGGAGAAGAAGCCCAAATTATCGCTGATAAACTT
    TCAGAGGTGGATAGTGAGCATAAAGAGACTTATCAAAAAAATGCGCAAGCCTTTATCAAA
    AAAGCTCAGGAATTGACTAAGAAATTCCAGTCTAAATTTGAAAAAGCGACTCAGAAAACA
    TTTGTAACACAACATACAGCCTTTTCTTATCTAGCGAAGAGATTTGGGCTTAATCAACTT
    GGTATTGCAGGCATCTCTCCTGAACAAGAACCAAGTCCACGACAATTAACAGAAATTCAG
    GAATTTGTTAAAACCTATAAGGTTAAAACGATTTTTACAGAAAGTAATGCTTCTTCAAAA
    GTAGCTGAAACTCTTGTCAAATCAACAGGTGTGGGTCTTAAAACTCTGAATCCTTTAGAG
    GCAGACCCACAAAATGACAAGACCTATTTAGAAAATCTGGAAGAAAATATGAGTGTTCTA
    GCAGAAGAATTAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    918

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC09020 [new locus tag: SPNOXC_RS04885 ]
  • symbol: Lmb
  • description: laminin binding protein
  • length: 305
  • theoretical pI: 5.03294
  • theoretical MW: 33897.2
  • GRAVY: -0.417049

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate anchored repeat ABC transporter, substrate-binding protein (TIGR03772; HMM-score: 92.6)
  • TheSEED  :
    • Laminin-binding surface protein
  • PFAM:
    Chelatase (CL0043) ZnuA; Zinc-uptake complex component A periplasmic (PF01297; HMM-score: 227.5)
    and 4 more
    Peptidase_MH (CL0035) SpoIIP; Stage II sporulation protein P (SpoIIP) (PF07454; HMM-score: 16.1)
    no clan defined DUF1598; Protein of unknown function (DUF1598) (PF07643; HMM-score: 13.6)
    LEDGF; Lens epithelium-derived growth factor (LEDGF) (PF11467; HMM-score: 11.9)
    LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 9.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helix: 1
  • SignalP: Signal peptide LIPO(Sec/SPII) length 20 aa
    • SP(Sec/SPI): 0.012158
    • TAT(Tat/SPI): 0.000107
    • LIPO(Sec/SPII): 0.987443
    • Cleavage Site: CS pos: 20-21. LGA-CG. Pr: 0.9835
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32560 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKQNLFLVLLSVFLLCLGACGQKESQAGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKLSEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLEADPQNDKTYLENLEENMSVLAEELK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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