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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS09910 [old locus tags: SPNOXC17990 SPNOXC_17990 ]
  • pan locus tag?: PNEUPAN003615000
  • symbol: rnpA
  • pan gene symbol?: rnpA
  • synonym:
  • product: ribonuclease P protein component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS09910 [old locus tags: SPNOXC17990 SPNOXC_17990 ]
  • symbol: rnpA
  • product: ribonuclease P protein component
  • replicon: chromosome
  • strand: -
  • coordinates: 1828606..1828977
  • length: 372
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (1828606..1828977) NCBI
  • BioCyc: SPNOXC_RS09910 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1851 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    TTGAAGAAAAACTTTCGTGTAAAAAGAGAGAAAGATTTTAAGGCGATTTTCAAGGAGGGG
    ACAAGTTTTGCTAATCGCAAATTTGTGGTCTACCAATTAGAAAACCAGAAAAACCATTTT
    CGAGTAGGTCTATCAGTTAGCAAAAAACTGGGGAATGCCGTCACTAGAAATCAAATTAAG
    CGACGGATTCGGCATATTATCCAGAATGCAAAAGGGAGTCTGGTAGAAGATGTCGACTTT
    GTTGTCATTGCTCGAAAAGGAGTCGAAACCTTGGGATACGCAGAGATGGAGAAAAATCTA
    CTCCACGTATTAAAATTATCAAAGATTTACCAGGAAGGAAATGGGAGTGAAAAAGAAACT
    AAAGTTGACTAG
    60
    120
    180
    240
    300
    360
    372

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS09910 [old locus tags: SPNOXC17990 SPNOXC_17990 ]
  • symbol: RnpA
  • description: ribonuclease P protein component
  • length: 123
  • theoretical pI: 10.8281
  • theoretical MW: 14252.4
  • GRAVY: -0.638211

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 3.1.26.5?  ExPASy
    Ribonuclease P Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
  • ⊞TIGRFAM:
    Genetic information processing Transcription RNA processing ribonuclease P protein component (TIGR00188; EC 3.1.26.5; HMM-score: 103.6)
    and 1 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase T (TIGR01882; EC 3.4.11.-; HMM-score: 12.6)
  • TheSEED: see SPNOXC17990
  • PFAM:
    S5 (CL0329) Ribonuclease_P; Ribonuclease P (PF00825; HMM-score: 111)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009578
    • TAT(Tat/SPI): 0.001693
    • LIPO(Sec/SPII): 0.001839
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000739244 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGLSVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLHVLKLSKIYQEGNGSEKETKVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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