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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS10975 [old locus tags: SPNOXC19820 SPNOXC_19820 ]
  • pan locus tag?: PNEUPAN003950000
  • symbol: SPNOXC_RS10975
  • pan gene symbol?: parB
  • synonym:
  • product: ParB/RepB/Spo0J family partition protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS10975 [old locus tags: SPNOXC19820 SPNOXC_19820 ]
  • symbol: SPNOXC_RS10975
  • product: ParB/RepB/Spo0J family partition protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2036082..2036840
  • length: 759
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (2036082..2036840) NCBI
  • BioCyc: SPNOXC_RS10975 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2069 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGAAAAATTTGAAATGATTTCTATCACAGATATACAAAAAAATCCCTATCAACCCCGA
    AAAGAATTTGATAGAGAAAAGCTAGATGAACTAGCACAGTCTATCAAAGAAAATGGGGTC
    ATTCAACCGATTATTGTTCGTCAATCTCCTGTTATTGGTTATGAAATCCTTGCAGGAGAG
    AGACGCTATCGGGCTTCACTTTTAGCTGGTCTACGGTCTATCCCAGCTGTTGTTAAACAG
    ATTTCAGACCAAGAGATGATGGTCCAGTCCATTATTGAAAATTTACAGAGAGAAAATTTA
    AACCCAATAGAAGAAGCACGCGCCTATGAATCTCTCGTAGAGAAAGGATTCACCCATGCT
    GAAATTGCAGATAAGATGGGCAAGTCTCGTCCATATATCAGCAACTCCATTCGTTTACTT
    TCCTTGCCAGAACAGATTCTCTCAGAAGTAGAAAATGGCAAACTATCACAAGCCCATGCG
    CGTTCCCTAGTTGGGTTAAATAAGGAACAACAAGACTATTTCTTTCAACGGATTATAGAA
    GAAGATATTTCTGTAAGGAAGTTAGAAACTCTTCTGACAGAGAAAAAACAAAAGAAACAG
    CAAAAAACTAATCATTTCATACAAAATGAAGAAAAACAGTTAAGAAAACTACTCGGATTA
    GATGTAGAAATTAAACTATCTAAAAAAGACAGTGGAAAAATCATTATTTCTTTTTCAAAT
    CAAGAAGAATATAGTAGAATTATCAACAGCCTGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    759

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS10975 [old locus tags: SPNOXC19820 SPNOXC_19820 ]
  • symbol: SPNOXC_RS10975
  • description: ParB/RepB/Spo0J family partition protein
  • length: 252
  • theoretical pI: 9.14608
  • theoretical MW: 29183.3
  • GRAVY: -0.599603

⊟Function[edit | edit source]

  • TIGRFAM:
    nucleoid occlusion protein (TIGR04285; HMM-score: 223)
    ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 196.7)
    and 2 more
    PRTRC system ParB family protein (TIGR03734; HMM-score: 130.9)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions plasmid partitioning protein RepB (TIGR03454; HMM-score: 73.6)
  • TheSEED: see SPNOXC19820
  • PFAM:
    ParBc (CL0248) ParBc; ParB/Sulfiredoxin domain (PF02195; HMM-score: 99.6)
    and 9 more
    HTH (CL0123) HTH_ParB; HTH domain found in ParB protein (PF17762; HMM-score: 48.1)
    RepB; RepB plasmid partitioning protein (PF07506; HMM-score: 27.4)
    KorB; KorB domain (PF08535; HMM-score: 19.8)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 18.1)
    no clan defined Mu-like_Pro; Mu-like prophage I protein (PF10123; HMM-score: 16.8)
    HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 15)
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 14.8)
    Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 13.8)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9798
    • Cytoplasmic Membrane Score: 0.0116
    • Cell wall & surface Score: 0.0018
    • Extracellular Score: 0.0068
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004895
    • TAT(Tat/SPI): 0.000573
    • LIPO(Sec/SPII): 0.000455
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000410383 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPIIVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNPIEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHARSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLLGLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Anita Minnen, Laetitia Attaiech, Maria Thon, Stephan Gruber, Jan-Willem Veening
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae.
Mol Microbiol: 2011, 81(3);676-88
[PubMed:21651626] [WorldCat.org] [DOI] (I p)

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