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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 08-SEP-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39V
- locus tag: SPV_RS10945 [old locus tag: SPV_2069 ]
- pan locus tag?: PNEUPAN003950000
- symbol: SPV_RS10945
- pan gene symbol?: parB
- synonym:
- product: ParB/RepB/Spo0J family partition protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPV_RS10945 [old locus tag: SPV_2069 ]
- symbol: SPV_RS10945
- product: ParB/RepB/Spo0J family partition protein
- replicon: chromosome
- strand: +
- coordinates: 2045602..2046360
- length: 759
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NZ_CP027540 (2045602..2046360) NCBI
- BioCyc: see SPV_2069
- MicrobesOnline:
- PneumoBrowse: SPV_2069 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGGAAAAATTTGAAATGATTTCTATCACAGATATACAAAAAAATCCCTATCAACCCCGA
AAAGAATTTGATAGAGAAAAACTAGATGAACTAGCACAGTCTATCAAAGAAAATGGGGTC
ATTCAACCGATTATTGTTCGTCAATCTCCTGTTATTGGTTATGAAATCCTTGCAGGAGAG
AGACGCTATCGGGCTTCACTTTTAGCTGGTCTACGGTCTATCCCAGCTGTTGTTAAACAG
ATTTCAGACCAAGAGATGATGGTCCAGTCCATTATTGAAAATTTACAGAGAGAAAATTTA
AACCCAATAGAAGAAGCACGCGCCTATGAATCTCTCGTAGAGAAAGGATTCACCCATGCT
GAAATTGCAGATAAGATGGGCAAGTCTCGTCCATATATCAGCAACTCCATTCGTTTACTT
TCCTTGCCAGAACAGATTCTTTCAGAAGTAGAAAATGGCAAACTATCACAAGCCCATGCG
CGTTCCCTAGTTGGGTTAAATAAGGAACAACAAGACTATTTCTTTCAACGGATTATAGAA
GAAGATATTTCTGTAAGGAAATTAGAAGCTCTTCTGACAGAGAAAAAACAAAAGAAACAG
CAAAAAACTAATCATTTCATACAAAATGAAGAAAAACAGTTAAGAAAACTACTCGGATTA
GATGTAGAAATTAAACTATCTAAAAAAGACAGTGGAAAAATCATTATTTCTTTTTCAAAT
CAAGAAGAATATAGTAGAATTATCAACAGCCTGAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPV_RS10945 [old locus tag: SPV_2069 ]
- symbol: SPV_RS10945
- description: ParB/RepB/Spo0J family partition protein
- length: 252
- theoretical pI: 9.14608
- theoretical MW: 29153.3
- GRAVY: -0.589683
⊟Function[edit | edit source]
- TIGRFAM: nucleoid occlusion protein (TIGR04285; HMM-score: 223)ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 196.8)and 2 morePRTRC system ParB family protein (TIGR03734; HMM-score: 131.4)Mobile and extrachromosomal element functions Plasmid functions plasmid partitioning protein RepB (TIGR03454; HMM-score: 73.4)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: ParBc (CL0248) ParBc; ParB/Sulfiredoxin domain (PF02195; HMM-score: 99.7)and 9 moreHTH (CL0123) HTH_ParB; HTH domain found in ParB protein (PF17762; HMM-score: 49)RepB; RepB plasmid partitioning protein (PF07506; HMM-score: 27.6)KorB; KorB domain (PF08535; HMM-score: 19.7)HTH_3; Helix-turn-helix (PF01381; HMM-score: 18.1)no clan defined Mu-like_Pro; Mu-like prophage I protein (PF10123; HMM-score: 17.5)HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 15)HTH_23; Homeodomain-like domain (PF13384; HMM-score: 14.9)Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 13.8)Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 13.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9778
- Cytoplasmic Membrane Score: 0.0124
- Cell wall & surface Score: 0.0018
- Extracellular Score: 0.008
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004895
- TAT(Tat/SPI): 0.000573
- LIPO(Sec/SPII): 0.000455
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000410378 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPIIVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNPIEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHARSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLLGLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress: SPV_2069 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Anita Minnen, Laetitia Attaiech, Maria Thon, Stephan Gruber, Jan-Willem Veening
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae.
Mol Microbiol: 2011, 81(3);676-88
[PubMed:21651626] [WorldCat.org] [DOI] (I p)