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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 25-OCT-2019
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae NU83127
- locus tag: SPNU_0798 [new locus tag: EL277_RS04240 ]
- pan locus tag?: PNEUPAN001794000
- symbol: cdd
- pan gene symbol?: cdd-1
- synonym:
- product: Cytidine deaminase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNU_0798 [new locus tag: EL277_RS04240 ]
- symbol: cdd
- product: Cytidine deaminase
- replicon: chromosome
- strand: +
- coordinates: 798625..799014
- length: 390
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AP018936 (798625..799014) NCBI
- BioCyc: see EL277_RS04240
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0738 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
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241
301
361ATGGCGACTACTGAGTTGATTGAACTGGCAATTGAAACCAGCAAACATGCCTATGTCCCC
TATTCTCACTTTCCTATCGGAGCAGTTTTAGTAGCTAAAGACGGAAGTGTTTACACGGGA
GTGAATATTGAAAATGCTAGCTATCCTTTGACCAATTGCGGTGAGAGAACAGCTATTTTT
AAGGCTATATCTGAAGGCCAAAGAGAATTTTCAGAATTGATTGTCTATGGTCAAACTGAA
AAACCGATCTCGCCATGTGGTGCTTGTCGCCAAGTGATGGCTGAATTTTTTGAACAAGAT
CTAAAAGTGACCTTAGTCGCAAAAGATAAATCGACGGTCGAGATGACGGTCGGGGAATTA
CTTCCATACTCTTTTACAGACTTAAACTAG60
120
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240
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390
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNU_0798 [new locus tag: EL277_RS04240 ]
- symbol: Cdd
- description: Cytidine deaminase
- length: 129
- theoretical pI: 4.44985
- theoretical MW: 14175.1
- GRAVY: -0.00155039
⊟Function[edit | edit source]
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides cytidine deaminase (TIGR01354; EC 3.5.4.5; HMM-score: 152.1)and 2 morePurines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides cytidine deaminase (TIGR01355; EC 3.5.4.5; HMM-score: 57.6)putative CRISPR-associated protein, APE2256 family (TIGR02619; HMM-score: 12.4)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: CDA (CL0109) dCMP_cyt_deam_1; Cytidine and deoxycytidylate deaminase zinc-binding region (PF00383; HMM-score: 62.8)and 7 moredCMP_cyt_deam_2; Cytidine and deoxycytidylate deaminase zinc-binding region (PF08211; HMM-score: 37.7)LmjF365940-deam; A distinct subfamily of CDD/CDA-like deaminases (PF14421; HMM-score: 15.8)SNAD4; Secreted Novel AID/APOBEC-like Deaminase 4 (PF18750; HMM-score: 15.4)no clan defined DUF6510; Family of unknown function (DUF6510) (PF20120; HMM-score: 14.8)CDA (CL0109) APOBEC4_like; APOBEC4-like -AID/APOBEC-deaminase (PF18774; HMM-score: 12.4)APOBEC1; APOBEC1 (PF18769; HMM-score: 12.3)NAD1; Novel AID APOBEC clade 1 (PF18778; HMM-score: 12.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9836
- Cytoplasmic Membrane Score: 0.0035
- Cell wall & surface Score: 0.0025
- Extracellular Score: 0.0104
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.013318
- TAT(Tat/SPI): 0.000865
- LIPO(Sec/SPII): 0.001637
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: BBG34689 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGELLPYSFTDLN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0738 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]