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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 25-OCT-2019
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae NU83127
 - locus tag: SPNU_1818 [new locus tag: EL277_RS09605 ]
 - pan locus tag?: PNEUPAN003422000
 - symbol: lacF_6
 - pan gene symbol?: msmF
 - synonym:
 - product: Lactose transport system permease protein LacF
 
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
 - locus tag: SPNU_1818 [new locus tag: EL277_RS09605 ]
 - symbol: lacF_6
 - product: Lactose transport system permease protein LacF
 - replicon: chromosome
 - strand: -
 - coordinates: 1821703..1822575
 - length: 873
 - essential: unknown
 
⊟Accession numbers[edit | edit source]
- Location: AP018936 (1821703..1822575) NCBI
 - BioCyc: see EL277_RS09605
 - MicrobesOnline:
 - PneumoBrowse for strain D39V: SPV_1676 PneumoBrowse
 
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGGCTATTCGAAAATTTTTAAATAAATACTGGGGTTGGACTTTTTTGCTCATCCCGCTT
GCATTACAAGCTATCTTCTTTTACTTTCCGATGGTACAAGGTGCTTTCTATAGTTTGACT
AACTGGACTGGATTGACCTATAATTATAAATTTGTTGGTCTGAATAACTACAAATTGCTT
ATGATTGATGGGAAATTCTTTACAGCCATTGCTTTTACTTTGATTTTAACACTGGCATTG
ATTATTGGAGAGATTACAATTGGGATGGTTGTGGCTCGGGCCTTGAATTCTAAGATGAAA
GGGCAGACCTTCTTTAGAGCATGGTTCTTTTTCCCAGCGGTTTTGTCTGGTTTGACAGTT
TCCTTGATTTTTAAACAATTCTTTAACTATGGTCTTCCAACGATTGGAAAAATTTTAGGG
ATTAGTTTTTTACAAGAAAGTCTATTAGGAACACCGATCGGTGCGGTAGTAGCAACCATT
TTTGTTCTTCTATGGCAAGGAGTAGCAATGCCAATTATTCTCTTTCTTGCTGGTCTTCAG
AGTATTCCAAGTGATATTTTGGAGGCGGCATCAATTGATGGTGCAACAAGCAAACAAACT
TTTTGGAAGATTGAATTACCATATTTGCTACCAACGATTTCTATGGTTTTTATCCTAGCT
CTTAAGTCTGGTTTGACTGCCTTTGACCAAATTTTTGCCTTGACGAGTGGTGGCCCGAAT
AATGCTACAACGTCTCTTGGTCTTTTAGTCTATAACTATGCCTTCAAGAGTAATCAATAT
GGATATGCGAATGCAATTGCCTTGATTTTATTCTTAATTATTGGAATTGTTTCTTTTATC
CAAATCAAACTATCAAAGAAATTTGAAATCTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNU_1818 [new locus tag: EL277_RS09605 ]
 - symbol: LacF_6
 - description: Lactose transport system permease protein LacF
 - length: 290
 - theoretical pI: 10.1292
 - theoretical MW: 32206.3
 - GRAVY: 0.848621
 
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 37.8)NifC-like ABC-type porter (TIGR01581; HMM-score: 36.6)Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 32.5)Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 30.3)and 3 morecholine ABC transporter, permease protein (TIGR03416; HMM-score: 29.7)2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 11.5)2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 10.3)
 - TheSEED: data available for D39, Hungary19A-6, TIGR4
 - PFAM: BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 55)
 
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
 - modifications:
 - cofactors:
 - effectors:
 
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
 - Cytoplasmic Membrane Score: 10
 - Cellwall Score: 0
 - Extracellular Score: 0
 - Internal Helices: 7
 
 - DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
 - Cytoplasmic Membrane Score: 0.9999
 - Cell wall & surface Score: 0
 - Extracellular Score: 0.0001
 
 - SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.289657
 - TAT(Tat/SPI): 0.002676
 - LIPO(Sec/SPII): 0.01081
 
 - predicted transmembrane helices (TMHMM): 7
 
⊟Accession numbers[edit | edit source]
- GI:
 - RefSeq: BBG35699 NCBI
 - UniProt:
 
⊟Protein sequence[edit | edit source]
- MAIRKFLNKYWGWTFLLIPLALQAIFFYFPMVQGAFYSLTNWTGLTYNYKFVGLNNYKLLMIDGKFFTAIAFTLILTLALIIGEITIGMVVARALNSKMKGQTFFRAWFFFPAVLSGLTVSLIFKQFFNYGLPTIGKILGISFLQESLLGTPIGAVVATIFVLLWQGVAMPIILFLAGLQSIPSDILEAASIDGATSKQTFWKIELPYLLPTISMVFILALKSGLTAFDQIFALTSGGPNNATTSLGLLVYNYAFKSNQYGYANAIALILFLIIGIVSFIQIKLSKKFEI
 
⊟Experimental data[edit | edit source]
- protein localization:
 - interaction partners:
 
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1676 PneumoExpress
 
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]