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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: SPOH_0386 [new locus tag: EL271_RS02115 ]
  • pan locus tag?: PNEUPAN001319000
  • symbol: ilvH
  • pan gene symbol?: ilvH
  • synonym: ilvN
  • product: Putative acetolactate synthase small subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPOH_0386 [new locus tag: EL271_RS02115 ]
  • symbol: ilvH
  • product: Putative acetolactate synthase small subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 383963..384439
  • length: 477
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCGTAGAATGTTAACAGCAAAACTACAAAATCGTTCAGGAGTCCTCAATCGCTTTACA
    GGTGTCCTATCTCGTCGTCAGGTTAATATTGAAAGCATCTCTGTTGGAGCAACAGAAGAT
    CCGAATGTATCGCGTATCACTATTATTATTGATGTTGCTTCTCATGATGAAGTGGAGCAA
    ATCATCAAACAGCTCAATCGTCAGATTGATGTGATTCGCATTCGAGATATTACAGACAAG
    CCTCATTTGGAGCGCGAGGTGATTTTGGTTAAGATGTCAGCGCCAGCTGAGAAGAGAGCT
    GAGATTTTAGCGATTATTCAACCTTTCCGTGCAACAGTGGTAGACGTAGCGCCAAGCTCG
    ATTACCATTCAGATGACGGGAAATGCAGAAAAGAGCGAAGCCCTATTGCGAGTCATTCGC
    CCATACGGTATTCGCAATATTGCTCGAACGGGTGCAACTGGATTTACCCGCGATTAA
    60
    120
    180
    240
    300
    360
    420
    477

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPOH_0386 [new locus tag: EL271_RS02115 ]
  • symbol: IlvH
  • description: Putative acetolactate synthase small subunit
  • length: 158
  • theoretical pI: 10.9758
  • theoretical MW: 17694.4
  • GRAVY: -0.136076

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Pyruvate family acetolactate synthase, small subunit (TIGR00119; EC 2.2.1.6; HMM-score: 177.5)
    and 6 more
    Metabolism Amino acid biosynthesis Aspartate family aspartate kinase, monofunctional class (TIGR00656; EC 2.7.2.4; HMM-score: 24.9)
    Metabolism Amino acid biosynthesis Serine family phosphoglycerate dehydrogenase (TIGR01327; EC 1.1.1.95; HMM-score: 20)
    Cellular processes Cellular processes Adaptations to atypical conditions RelA/SpoT family protein (TIGR00691; HMM-score: 16.5)
    Metabolism Energy metabolism Amino acids and amines tryptophan 5-monooxygenase (TIGR01270; EC 1.14.16.4; HMM-score: 15.7)
    Hypothetical proteins Conserved TIGR02147 family protein (TIGR02147; HMM-score: 13.6)
    Metabolism Amino acid biosynthesis Aspartate family aspartate kinase (TIGR00657; EC 2.7.2.4; HMM-score: 12.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    ACT (CL0070) ALS_ss_C; Small subunit of acetolactate synthase (PF10369; HMM-score: 89.8)
    and 5 more
    ACT; ACT domain (PF01842; HMM-score: 52.9)
    ACT_5; ACT domain (PF13710; HMM-score: 50)
    ACT_4; ACT domain (PF13291; HMM-score: 35.5)
    ACT_6; ACT domain (PF13740; HMM-score: 18.9)
    no clan defined DUF5301; Domain of unknown function (DUF5300) (PF17225; HMM-score: 16.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007876
    • TAT(Tat/SPI): 0.006729
    • LIPO(Sec/SPII): 0.002106
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG36418 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVSRITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEILAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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