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serotype 4
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serotype 19A
Hu17
serotype 19A
INV104
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INV200
serotype 14
JJA
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MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
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OXC141
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serotype 1
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serotype 2
SP49
serotype 19A
SPN032672
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SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_1329 [new locus tag: SPP_RS06560 ]
  • pan locus tag?: PNEUPAN002570000
  • symbol: SPP_1329
  • pan gene symbol?: —
  • synonym:
  • product: HD superfamily phosphohydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_1329 [new locus tag: SPP_RS06560 ]
  • symbol: SPP_1329
  • product: HD superfamily phosphohydrolase
  • replicon: chromosome
  • strand: +
  • coordinates: 1245780..1247084
  • length: 1305
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAACGAAAAAGTATTCCGTGACCCAGTTCACAACTACATCCATGTCATTAATCAAATC
    ATCTATGACTTGATTAATACAAAAGAATTTCAGCGTTTGCGCCGGATCAAACAACTGGGA
    ACTTCCAGTTATACCTTCCACGGTGGAGAACACAGTCGCTTCTCTCACTGTCTAGGAGTC
    TATGAAATTGCACGACGCATCACAGAGATTTTCGAAGAAAAATATCCTGAGGAATGGAAT
    CCTGCCGAGTCTCTCTTGACCATGATCGCTGCTCTCCTACATGACCTTGGGCATGGCGCC
    TACTCCCATACTTTTGAACATCTCTTTGATACAGACCATGAAGCTATTACTCAGGAGATT
    ATTCAAAGTCCTGAGACAGAGATTCACCAAGTCTTGCTACAAGTAGCGCCCGATTTTCCA
    GAGAAAGTTGCCAGTGTCATAGACCATACCTATCCTAACAAGCAGGTCGTACAACTCATT
    TCTAGTCAGATTGACGCAGATCGCATGGACTATCTCTTGCGTGACTCCTATTTTACAGGA
    GCATCCTATGGGGAATTTGACCTGACTCGAATCCTCCGAGTCATTCGTCCTATCGAAAAT
    GGTATCGCCTTTCAGCGCAATGGCATGCACGCCATCGAAGACTATGTCCTCAGTCGCTAC
    CAGATGTATATGCAGGTCTATTTCCACCCAGCAACACGCGCTATGGAAGTTCTCCTACAG
    AATCTTCTCAAGCGCGCTAAGGAACTCTACCCTAAGGACAAAGACTTCTTTGCACGAACT
    TCCCCACACCTCCTGCCTTTCTTTGAAAAAAATGTGACCTTGTCTGACTATCTGGCTCTA
    GATGATGGTGTGATGAATACCTACTTCCAGCTCTGGATGACCAGTCCTGACAAAATTCTC
    GCAGATTTATCGCAACGCTTTGTCAACCGCAAGGTCTTTAAATCCATTACCTTTTCACAA
    GAAGATCAAGACCAACTCGCTAGCATGAGAAAATTGGTTGAGGACATTGGCTTTGATCCC
    GACTACTATACTGCCATTCATAAGAACTTTGACCTCCCTTATGATATCTATCGTCCCGAA
    TCTGAAAATCCACGGACACAGATTGAGATTTTACAAAAGAATGGAGAACTGGCCGAACTC
    TCTAGCCTGTCTCCTATCGTCCAATCCCTTGCTGGTAGTCGTCACGGAGATAATCGTTTC
    TATTTTCCGAAAGAAATGTTAGATCAAAACAGTATCTTTGCTAGCATTACCCAGCAATTT
    TTATACTTGATTGAGAACGATCATTTTACCCCAAATAAAAACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1305

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_1329 [new locus tag: SPP_RS06560 ]
  • symbol: SPP_1329
  • description: HD superfamily phosphohydrolase
  • length: 434
  • theoretical pI: 5.53843
  • theoretical MW: 50821.1
  • GRAVY: -0.42788

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions putative dGTPase (TIGR01353; EC 3.1.5.1; HMM-score: 25.5)
    and 4 more
    HDIG domain (TIGR00277; HMM-score: 16.1)
    CRISPR-associated endonuclease Cas3-HD (TIGR01596; EC 3.1.-.-; HMM-score: 14.1)
    CRISPR-associated helicase Cas3, subtype I-F/YPEST (TIGR02562; HMM-score: 12.2)
    phosphonate degradation operons associated HDIG domain protein (TIGR03276; HMM-score: 9.4)
  • TheSEED  :
    • Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)
    Nucleosides and Nucleotides Purines Purine conversions  Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)
  • PFAM:
    HD_PDEase (CL0237) HD; HD domain (PF01966; HMM-score: 51.8)
    and 5 more
    no clan defined HD_assoc_2; HD associated region (PF19276; HMM-score: 39.6)
    HD_PDEase (CL0237) PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase (PF00233; HMM-score: 17.6)
    no clan defined RNR_N; Ribonucleotide reductase N-terminal (PF08343; HMM-score: 14.3)
    FliG (CL0436) FliG_N; FliG N-terminal domain (PF14842; HMM-score: 12.5)
    no clan defined CTD9; C-terminal domain 9 of the ABC-three component (ABC-3C) systems (PF20285; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9469
    • Cytoplasmic Membrane Score: 0.0465
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0058
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008631
    • TAT(Tat/SPI): 0.000795
    • LIPO(Sec/SPII): 0.000427
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO20914 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSYTFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYSHTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLISSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLSRYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSDYLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVEDIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAGSRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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