From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_RS03340 [old locus tag: SPP_0684 ]
  • pan locus tag?: PNEUPAN001606000
  • symbol: SPP_RS03340
  • pan gene symbol?: zmpB
  • synonym:
  • product: G5 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_RS03340 [old locus tag: SPP_0684 ]
  • symbol: SPP_RS03340
  • product: G5 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 624113..629755
  • length: 5643
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    GTGTTTAAAAAAGACCGTTTTTCAATTCGTAAGATTAAGGGAGTTGTAGGCTCTGTATTT
    CTTGGAAGCCTTTTGATGGCTCCTTCTGTAGTGGACGCAGCCACCTATCACTATGTAAAT
    AAAGAGATTATTTCACAAGAAGCTAAAGATTTAATTCAGACAGGAAAGCCTGACAGGAAT
    GAAGTTGTATATGGTTTGGTGTATCAAAAAGATCAGTTTCCTCAAACAGGGACAGAAGCA
    TCTGTTTTGACAGCTTTTGGTTTGCTGACTGTTGGGAGCTTGCTTTTAATCTACAAGAGA
    AAGAAAATTGCTAGCGTCTTTCTAGTTGGAGCTATGGGATTGGTAGTTCTTCCTAGTGCA
    GGGGCTGTAGACCCAGTTGCGACCCTAGCGCTGGCTAGTCGAGAGGGTGTTGTTGAAATG
    GATGGCTATCGCTATGTTGGTTATCTATCAGGTGACATCCTCAAAACGCTTGGCTTGGAC
    ACTGTTTTAGAAGAAACCTCAGCAAAACCTGGAGAGGTGACTGTAGTCGAAGTTGAGACT
    CCTCAATCAACAACAAATCAGGAGCAAGCTAGGACAGAAAACCAAGTAGTAGAGACAGAG
    GAAGCTCCAAAAGAAGAAGCACCTAAAACAGAAGAAAGTCCAAAGGAAGAACCAAAATCG
    GAGGTAAAACCTACTGACGACACCCTTCCTAAAGTAGAAGAGGGGAAAGAAGATTCAGCA
    GAACCAGCTCCAGTTGAAGAAGTAGGTGGAGAAGTTGAGTCAAAACCAGAGGAAAAAGTA
    GCAGTTAAGCCAGAAAGTCAACCATCAGACAAACCAGCTGAGGAATCAAAAGTTGAACCA
    CCAGTAGAACAAGCAAAAGTCCCAGAACAACCCGTGCAACCTACACAAGCTGAGCAACCA
    AGTACACCAAAAGAATCATCACAACAAGAAAATCCTAAAGAAGATAGGGGAGCGGAAGAG
    ACACCGAAACAAGAAGATGAACAGCCAGCAGAAGCCCCAGAAATCAAGGTTGAAGAACCA
    GTAGAATCAAAAGAGGAGACTAAAACAGCTAAAGGTACGCAAGAAAAAGGTCACGTGGGT
    GAGGCTCTTGCTCAAGAACAATTACCTGAGTACAAAGTAACTGAGGGAACCCTTGTTGAA
    ACATCGACTACAGACCTAGACTACAAAACTGAAACGACTGAGGATCCAACCAAGTATACG
    GACGAAGAAACTGTCCTACGAACTGGTGAAAAAGGAAGTCAAGTTACAAAAACAACCTAT
    AAAACAGTAGAAGGTGTTAAAACTGACCAAGTTCTTTCAACCAGTACGGAAGTGACCAAG
    GAGCCTGTAAATCAACAGGTAATCCGTGGTACAAAACCAATTGAAGGAACTCTTATAGAA
    GAAAGTCTTGAAAAGATTCCATTTAAGGAAGTTGTTAAAGAAGATGACCAACTGAAAAAA
    GGCTTAGAAGTTGTAGCTCAAGAAGGAAAAGAAGGCCAGAAAAAAATCACCAAGACCTTT
    AATACCATTAAGGGAGTTAAAACAGAAGACGCTCCAAAAGTTACAGAGGAAATCCTTGAG
    GAACCTCAAGACAAAATTTTGAAACGTGGTACCAAGAGCTTTGAAAAACCAGTGTTGACC
    ATCACAGAAATTGAATCTAAGGATTTGAAGCGTACTTCAGATGTTAAGTATAGTTTAGAA
    AATCCAAGTAAGGCAGCCATTAAATCTATTACCCTAACTCTGAAAAAAGGTGATGAGATT
    GTCAAAACCTTGAATGTTTCACCAGAAGACTTGACAACTACCCTGACAGATTTGCAGTAC
    TACAAGGATTATAAACTTGAAACAAAGATGGTTTATGACCGTGGTGAGGGGGATGAGGAA
    GAAGTTCTGAAAGAAGAACCGCTAAGAATTGATCTCAAAAAAGTTGAAATAAAAGATATT
    ATAAGAACGGATTTAATCAAATATGAAAACCAAGTTGAAACTGATGAAACTCGATTGACT
    TCAGTGCCAACTGATTTGTCAAATTATTATTTAAAAGTTACCTCTAATGACCATAAGACC
    AATCTACTAGCGGTTCAAAAAATTGAAGAGTCAACAATTGATGGAAAACAAGTCTACAAG
    GTAATAGCAGTAGCGGATAACTTGGTCCAACGTAATGTCGATAATCGCTTTGAAGAAACT
    TATACCTACTATATTGAAAAACCCAAAGCTAGTCAGGCTGGTATTTTCTACGACTTTGAA
    GAATTGATCCAAGCCATTCAGACAAATCCTGCCGGTGAATTTAAACTGGGTCAAAGCATG
    AGCGCTCGTAACGTTGTTCCTAAAGGGAAATCTTATATTACTTCAGAGTTTACTGGTAAA
    CTATTGAGTGATGGTGATAAACGCTATGCTATCCATAATTTGGAACATCCTTTATTCGAT
    AAGATTAAGGCTGGAACTGTTAAAAATATAAATTTTGAAAATATTGATATTGATTTATCT
    AATCAAGATAATATCGCTGCAATAGCAAATGAAATCAGTGGAACGACACGTATAGAAAAT
    ATCAAAGCAATCGGAACCATAACAGCTAGAAATAATGTTGCTGGGTTCGTAAATAACATA
    AAAGAAGACGCTACTTTAGAAAATGTGGCATTTATCGGTAGTATAAATTCTGCTGGTAAT
    AATTCAACAGTTGGAGGTATTGCCGGTTCTAACTATATGGGGTTTGTTAATAGAGCCTAC
    GTTGATGCTACTATTACAGCAAATAACGCAAATGCAAGTATGCTTGTTCCTTTCGTTCAA
    TATAAAGCTCATAGCTGGCTATCAGGGACAAAAGGAAAACTTACAAACTCTGTAGCAAAA
    GGTATTCTTGATGTTAAAAATACTAAATATGTTGGTGGAATAACCTCTAAAACTTGGCCA
    TATGGAGCGGTTCAAGATAATGTAACATATGCGAAAGTTATTAAAGGTCAGGAAATATTC
    GGTTCAAACGATGTTAATGATGGAGATGCAAATCCTTTTGTGTCTAATTTATTTGGAGTT
    ATTGGATATAGCTCTTCTGAAGATGGAACTGGTAAAGATAATAAAAACAAAAATAAATTA
    AAACACTTATCTAAATCTGAGGCTGATGCAAAAGTTGCTAGTTTCAATATTACTGCTGCT
    AAATTCGTAAGTGAACCTTATGAATTGAACAAATTGAATAATGTTAGCAGTCGTGAAGCA
    GCTTACGAGTCTATTCAAGATTATAATGCAGACTATAAACTTGCTTATAAGAATATTGAA
    AAACTACAACCATTCTATAACAAAGATTTTATCGTTAATCAAGCTAATAAACTAGATAAG
    AACAACAAGTTAAATACTAAAGAGATTCTATCGGTTACTCCTATGAACAATAATAACTTT
    GTAACTGATTTAGGTGATGCAAACAAAATTATCGTTCATTATGCTGATGGAACAAAAGAC
    TACTTCAACCTATCTTCTAGTGATGAAGGTCTAAGTAATGTTAGAGAATACACTATAACT
    GACTTAGGTATTAAATATACACCTAATATCGTTCAAAAAGATCATAGTGCTTTAATTAAC
    GGTATCGTAAATATCTTAAGCCCTATTGAGCTTCAATCTAATCCAATTTACCAAAAACTT
    GGCAGAACAGGGTCTAATAGAGTAAATGCAATTAAAGACCTTTATTTAGAAGAAAGTTTT
    GACCATGTAAAAGCTAATTTAAACATATTAGTAACTAAATTAGTTGAAAATGAAGATCAT
    CAACTGAATAATTCATCTGCAGCTCAACAAATGATTCTTGATAAAGTTGAGAAAAATAAA
    GCTGCCCTATTATTAGGTTTAACATACTTAAACCGTTACTACGGTGTTAAATTCGGTGAT
    GTTAACATTAAAGAATTAATGTTATTCAAACCAGATTTCTATGGTAAAAATGTAAGTGTA
    TTAGATAGATTAATTGAAATCGGTTCAAGAGAAGATAATATAAAAGGTCATCGGACATAT
    GATGCTTTCAGCGAGATTATTTCTAAGACAACCTTATCAGAAAATTTGGTAAACTTTTTA
    AATTATAATCGTCGACTATTTACTGCAGATGTAAATATTTATGATTGGTTTAAGAAAGCT
    ACAGAAGGGAATGTCTATATAGCGGAGCGTGCTTCGGAAGTCGATGAAATTAAAGCGGCG
    AAATATAAAGTTTGGGATAATTTACAATCTGCTACTCATCGGAAGATGATACTCCCATTA
    TTAAATCTAAATAAATCACATGTGTATTTAATCTCGAATTATAGTGCAATGGCTGTTGGA
    ACAGCAGAAAAGTTAGGGCATAGCTCCTTCGATGGAATAAAAAATCAGATTGAAAAAGCA
    GCGGACAGTTATCGAAATTATTTTGATTTTTGGTATAGATTATCTTTAGATAAGGTTAAG
    AATATGCTAGTCAAAAATACAGTAACTCCTCTTTGGGAAGGTTATCAAGCACCTGGTGGA
    TGGCCTGATAAGTATGGTAAGAGAAATAATAAAGAAGACTATGCCCCATTGAGAGAGTTG
    TTTGGACCTATTGGTAAGTATTATGGTAACAATGGAACAGGTGCTTATGCAGTTATTTGG
    GATAATCCTTTGGATACGCGAACAGAAGTAAATTATATTGCATTAAGTATGATTGATGAG
    TTTGGAATCTCTGTTTATACACATGAAACTACTCATGTTAATGATCGTGCAATCTATTTA
    GGAGGATATGGACGTCGCTCAGGGACTCATGCAGAAGCCTATGCACAAGGAATGTTACAA
    ACACCAGTACCAAGTACATGGTTTGATGAATACGGTGCTTTGGGAATTAATATGACTTTC
    TATCGTCCAAATGATGGAAATCAGTGGTATATTACCGATCCGAAGACTCTTAAAACAAGA
    GAAGACATTGATAATTATATGAAAGGCTATATAGATACCTTGTCTCTTCTTGATTATGTT
    GAAGGTGATGCAGTCATTAGTAAACATGATGATAAATTAAATCAACTGTGGTTTAAGAAA
    GTTGATCCTATTGAACGCACTGTAGGGTCAAAAGATCAATATGACAAGGTTCGAAATATG
    AGCTCTGATGATTGGAAAGGAATAACATTAAACAGTGTTAATGACTTAGTTGATAATAAT
    CTGATGACTAATCGTATGATGAATAATAATATATATAAGCCAGAAGTATTTGATCCAGGT
    ATTGCCTATGTAGGAATTAAAATGATGAATAGTATCTATGCAGGTAACACAAGTGAGGGT
    GCACCCGGTGCTGTTACATTTAAGAATAATGCATTTAGACTCTGGGGATATTATGGCTAT
    GATAAAGGATTCTTAGGATATGCTTCAGATAAATTAAAATCTCAAGCTAATAAAGAAGGG
    AAACAATTTGGAGATCAATATATTATACAAAAAATATCTGACGGCAGATTCCAATCGTTT
    GCTGATTTTAAGAAAGAATATTATAAAGAATTGTTAGAAAAAGCCAACGCTGGTTTTACT
    CCTTTTACTATTGATGGTGAGACCATTCATAACTATGATGAATTAAAATCATTATTTGCC
    AAAGCTCTTGAAGAAGATATGGTTACTAATAAAGTTAATGGTAAACTTGTGCAAGTAAAA
    GAAAAAGTTTATAAGAAACTTCTTCAACAAACAAATAGCTTTAAAACTTCAATCTTTAAA
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4980
    5040
    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5643

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_RS03340 [old locus tag: SPP_0684 ]
  • symbol: SPP_RS03340
  • description: G5 domain-containing protein
  • length: 1880
  • theoretical pI: 4.99039
  • theoretical MW: 210414
  • GRAVY: -0.591117

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 22.8)
  • TheSEED: see SPP_0684
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 677.8)
    and 5 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 283.9)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 75.4)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 22.9)
    RusA; Endodeoxyribonuclease RusA (PF05866; HMM-score: 18)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • SignalP: Signal peptide SP(Sec/SPI) length 33 aa
    • SP(Sec/SPI): 0.98483
    • TAT(Tat/SPI): 0.008282
    • LIPO(Sec/SPII): 0.001095
    • Cleavage Site: CS pos: 33-34. VDA-AT. Pr: 0.9782
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000472960 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEIISQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKKIASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLDTVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEESKVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPEIKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTETTEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKTEDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAAIKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLKEEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNLLAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFEELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPLFDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGFVNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASMLVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAKVIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADAKVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNKDFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSSSDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTGSNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTYDAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIKAAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQIEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDYAPLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTHVNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWYITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTVGSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGIKMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFGDQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKALEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi, Marco R Oggioni
The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice.
BMC Microbiol: 2003, 3;14
[PubMed:12841855] [WorldCat.org] [DOI] (I e)C E Blue, G K Paterson, A R Kerr, M Bergé, J P Claverys, T J Mitchell
ZmpB, a novel virulence factor of Streptococcus pneumoniae that induces tumor necrosis factor alpha production in the respiratory tract.
Infect Immun: 2003, 71(9);4925-35
[PubMed:12933834] [WorldCat.org] [DOI] (P p)

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPP_RS03340&oldid=122781"