Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 15-OCT-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae P1031
- locus tag: SPP_RS06035 [old locus tag: SPP_1217 ]
- pan locus tag?: PNEUPAN000484000
- symbol: SPP_RS06035
- pan gene symbol?: phtD
- synonym: phtB
- product: pneumococcal-type histidine triad protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPP_RS06035 [old locus tag: SPP_1217 ]
- symbol: SPP_RS06035
- product: pneumococcal-type histidine triad protein
- replicon: chromosome
- strand: -
- coordinates: 1136859..1139393
- length: 2535
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012467 (1136859..1139393) NCBI
- BioCyc: SPP_RS06035 BioCyc
- MicrobesOnline: see SPP_1217
- PneumoBrowse for strain D39V: SPV_2265 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521ATGAAAATCAATAAAAAATATCTAGCTGGGTCAGTAGCTACACTTGTTTTAAGTGTCTGT
GCTTATGAACTAGGTTTGCATCAAGCTCAAACTGTAAAAGAAAATAATCGTGTTTCCTAT
ATAGATGGAAAACAAGCGACGCAAAAAACGGAGAATTTGACTCCTGATGAGGTTAGCAAG
CGTGAAGGAATCAATGCCGAACAAATCGTCATCAAAATAACAGACCAAGGCTATGTCACT
TCACATGGGGACCACTATCATTATTACAATGGTAAGGTTCCTTATGACGCTATCATCAGT
GAAGAATTGCTGATGAAGGATCCAAACTACCAGCTAAAGGACGAGGATATTATCAGTGAA
ATCAAGGGTGGTTATGTGATTAAGGTAGATGGAAAATACTATGTTTACCTTAAGGATGCA
GCTCATGCGGATAATGTCCGTACAAAAGAAGAAATCAATCGACAAAAACAAGAGCATAGT
CAACATCGTGAAGGTGGGACTCCAAGAAACGATGGTGCTGTTGCCTTGGCACGTTCACAG
GGACGCTACACCACAGATGATGGTTATATCTTTAATGCTTCTGATATCATTGAAGATACT
GGTGATGCTTATATCGTTCCTCACGGCGACCATTACCATTACATTCCTAAGAATGAGTTA
TCAGCTAGCGAGTTAGCTGCTGCAAAAGCCTTCCTATCTGGTCGGGGAAATCTGTCAAAT
TCAAGAACCTATCGCCGACAAAATAGCGATAACACTTCAAGAACAAACTGGGTACCTTCT
GTAAGCAATCCAGGAACTACAAATACTAACACAAGCAACAACAGCAACACTAACAGTCAA
GCAAGTCAAAGTAATGACATTGATAGTCTCTTGAAACAGCTCTACAAACTGCCTTTGAGT
CAACGCCATGTAGAATCTGATGGCCTTATTTTCGACCCAGCGCAAATCACAAGTCGAACC
GCCAATGGTGTTGCTGTACCGCACGGAGACCATTATCACTTTATTCCTTATTCACAACTG
TCACCTTTGGAAGAAAAATTGGCTCGTATTATTCCCCTTCGTTATCGTTCAAACCATTGG
GTACCAGATTCAAGACCAGAACAACCAAGTCCACAACCGACTCCGGAACCTAGTCCAAGT
CCGCAACCTGCACCAAATCCTCAACCAGCTCCAAGCAATCCAATTGATGAGAAATTGGTC
AAAGAAGCTGTTCGAAAAGTAGGCGATGGTTATGTCTTTGAGGAGAATGGAGTTCCTCGT
TATATCCCAGCCAAGGATCTTTCAGCAGAAACAGCAGCAGGCATTGATAGCAAACTGGCC
AAGCAGGAAAGTTTATCTCATAAGCTAGGAGCTAAGAAAACTGACCTCCCATCTAGTGAT
AGAGAATTTTACAATAAGGCTTATGACTTACTAGCAAGAATTCATCAAGATTTACTTGAT
AATAAAGGTCGACAAGTTGATTTTGAGGCTTTGGATAACCTGTTGGAACGACTCAAGGAT
GTCTCAAGTGATAAAGTCAAGTTAGTGGAAGATATTCTTGCCTTCTTAGCTCCGATTCGT
CATCCAGAACGTTTAGGAAAACCAAATGCGCAAATTACCTACACTGATGATGAGATTCAA
GTAGCCAAGTTGGCAGGCAAGTACACAACAGAAGACGGTTATATCTTTGATCCTCGTGAT
ATAACCAGTGATGAGGGGGATGCCTATGTAACTCCACATATGACCCATAGCCACTGGATT
AAAAAAGATAGTTTGTCTGAAGCTGAGAGAGCGGCAGCCCAGGCTTATGCTAAAGAGAAA
GGTTTGACCCCTCCTTCGACAGACCATCAGGATTCAGGAAATACTGAGGCAAAAGGAGCA
GAAGCTATCTACAACCGCGTGAAAGCAGCTAAGAAGGTGCCACTTGATCGTATGCCTTAC
AATCTTCAATATACTGTAGAAGTCAAAAACGGTAGTTTAATCATACCTCATTATGACCAT
TACCATAACATCAAATTTGAGTGGTTTGACGAAGGCCTTTATGAGGCACCTAAGGGGTAT
AGTCTTGAGGATCTTTTGGCGACTGTCAAGTACTATGTCGAACATCCAAACGAACGTCCG
CATTCAGATAATGGTTTTGGTAACGCTAGCGACCATGTTCAAAGAAACAAAAATGGTCAA
GCTGATACCAATCAAACGGAAAAACCAAACGAGGAGAAACCTCAGACAGAAAAACCTGAG
GAAGAAACCCCTCGAGAAGAGAAACCGCAAAGCGAGAAACCAGAGTCTCCAAAACCAACA
GAGGAACCAGAAGAAGAATCACCAGAAGAATCACCAGAGGAATCAGAAGAACCTCAGGTC
GAGACTGAAAAGGTTAAAGAAAAACTGAGAGAGGCTGAAGATTTACTTGGAAAAATCCAG
AATCCAATTATCAAGTCCAATGCCAAAGAGACTCTCACAGGATTAAAAAATAATTTACTA
TTTGGCACCCAGGACAACAATACTATTATGGCAGAAGCTGAAAAACTATTGGCTTTATTA
AAGGAGAGTAAGTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1200
1260
1320
1380
1440
1500
1560
1620
1680
1740
1800
1860
1920
1980
2040
2100
2160
2220
2280
2340
2400
2460
2520
2535
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPP_RS06035 [old locus tag: SPP_1217 ]
- symbol: SPP_RS06035
- description: pneumococcal-type histidine triad protein
- length: 844
- theoretical pI: 5.26171
- theoretical MW: 94739
- GRAVY: -0.930687
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Pathogenesis streptococcal histidine triad protein (TIGR01363; HMM-score: 741.3)and 1 morecobaltochelatase subunit (TIGR02442; EC 6.6.1.2; HMM-score: 5.4)
- TheSEED: see SPP_1217
- PFAM: no clan defined Strep_his_triad; Streptococcal histidine triad protein (PF04270; HMM-score: 249.9)and 2 morePHtD_u1; Unstructured region on Pneumococcal histidine triad protein (PF16645; HMM-score: 93.3)RNR_Alpha; Ribonucleotide reductase alpha domain (PF17975; HMM-score: 14.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: Signal peptide LIPO(Sec/SPII) length 19 aa
- SP(Sec/SPI): 0.378356
- TAT(Tat/SPI): 0.001471
- LIPO(Sec/SPII): 0.586
- Cleavage Site: CS pos: 19-20. LSV-CA. Pr: 0.5552
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000700264 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGKQATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAKAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator: AdcR* see SPP_1217
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_2265 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.