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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 25-NOV-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae R6
- locus tag: SPR_RS03340 [old locus tag: spr0665 ]
- pan locus tag?: PNEUPAN001696000
- symbol: prfB
- pan gene symbol?: prfB
- synonym:
- product: peptide chain release factor 2
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPR_RS03340 [old locus tag: spr0665 ]
- symbol: prfB
- product: peptide chain release factor 2
- replicon: chromosome
- strand: +
- coordinates: join(668364..668435,668437..669459)
- length: 1095
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NC_003098 join(668364..668435,668437..669459) NCBI
- BioCyc: see spr0665
- MicrobesOnline: see spr0665
- PneumoBrowse for strain D39V: SPV_0658 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1021
1081ATGGACATTTCAGTAATTCGTCAGAAAATTGACGCAAATCGTGAAAAATTAGCTTCTTTC
AGGGGGTCTCTTGACCTCGAAGGGCTAGAGGAAGAGATTGCCATCTTGGAAAACAAGATG
ACAGAACCTGATTTTTGGAACGATAATATTGCGGCCCAAAAAATGTCGCAAGAATTAAAT
GAATTAAAAAACACTTACAATACCTTCCATAAGATGGAAGAGTTGCAGGATGAAGTCGAA
ATTTTATTGGATTTTTTGGCTGAAGACGAGTCAGTGCATGATGAACTGGTAGCGCAGTTA
GCCGAACTTGATAAGATAATGACCAGCTACGAGATGACTCTACTCTTGTCAGAACCTTAT
GACCACAACAATGCCATCTTGGAAATCCATCCAGGTTCTGGTGGTACTGAGGCGCAGGAC
TGGGGTGATATGTTGCTTCGTATGTATACTCGTTATGGTAATGCTAAAGGCTTTAAAGTG
GAAGTGTTGGATTACCAAGCAGGTGATGAGGCTGGTATTAAGTCGGTAACTTTATCATTT
GAAGGGCCTAATGCCTATGGTCTCCTCAAGTCAGAAATGGGTGTTCACCGCTTAGTGCGA
ATCTCACCATTTGACTCTGCCAAACGTCGCCATACCTCTTTCACATCTGTAGAAGTGATG
CCAGAATTGGATGATACTATTGAAGTGGAAATCCGTGAAGATGATATCAAGATGGATACC
TTCCGTTCAGGTGGTGCCGGTGGACAAAACGTCAATAAGGTTTCAACAGGTGTACGTTTA
ACCTACATTCCAACTGGAATTGTTGTCCAATCAACAGTGGATCGTACCCAGTATGGAAAT
AGAGATCGCGCCATGAAGATGTTGCAGGCTAAGCTCTATCAAATGGAGCAAGAGAAGAAG
GCTGCGGAGGTAGATTCTCTCAAAGGTGAGAAAAAGGAGATCACTTGGGGAAGCCAAATC
CGTTCTTATGTCTTCACGCCTTATACTATGGTAAAAGATCACCGAACTAGCTTTGAGGTT
GCTCAGGTAGATAAGGTTATGGATGGGGACCTAGATGGTTTTATCGATGCTTATCTCAAG
TGGCGAATTAGCTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPR_RS03340 [old locus tag: spr0665 ]
- symbol: PrfB
- description: peptide chain release factor 2
- length: 364
- theoretical pI: 4.47618
- theoretical MW: 41429.4
- GRAVY: -0.508242
⊟Function[edit | edit source]
- TIGRFAM: Protein synthesis Translation factors peptide chain release factor 2 (TIGR00020; HMM-score: 499.5)and 2 moreProtein synthesis Translation factors peptide chain release factor 1 (TIGR00019; HMM-score: 272.1)Protein synthesis Translation factors putative peptide chain release factor H (TIGR03072; HMM-score: 100.2)
- TheSEED: see spr0665
- PFAM: no clan defined PCRF; PCRF domain (PF03462; HMM-score: 202.7)and 3 moreRF (CL0337) RF-1; RF-1 domain (PF00472; HMM-score: 132.1)no clan defined ABC_tran_CTD; ABC transporter C-terminal domain (PF16326; HMM-score: 24)DUF3829; Protein of unknown function (DUF3829) (PF12889; HMM-score: 11)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9923
- Cytoplasmic Membrane Score: 0.0007
- Cell wall & surface Score: 0
- Extracellular Score: 0.007
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001908
- TAT(Tat/SPI): 0.000295
- LIPO(Sec/SPII): 0.000393
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPDFWNDNIAAQKMSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAELDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKVEVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVEVMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTYIPTGIVVQSTVDRTQYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDHRTSFEVAQVDKVMDGDLDGFIDAYLKWRIS
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: prfB > ftsE > ftsX
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0658 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]