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serotype 1

NCBI: 25-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: SPR_RS07975 [old locus tag: spr1607 ]
  • pan locus tag?: PNEUPAN003242000
  • symbol: SPR_RS07975
  • pan gene symbol?: rsmE
  • synonym:
  • product: 16S rRNA (uracil(1498)-N(3))-methyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPR_RS07975 [old locus tag: spr1607 ]
  • symbol: SPR_RS07975
  • product: 16S rRNA (uracil(1498)-N(3))-methyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1583235..1583978
  • length: 744
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGCAGCAGTATTTTGTAAAAGGCAGTGCTATCTCTCCTGTCACTATCGAGGACAAGGAA
    ACCAGTAAGCATATGTTTCAGGTTATGCGCTTGAAAGAAGAGGATGAGGTTACCTTAGTC
    TTTGATGATGGCATCAAGCGCTTGGCGCGCGTGCTGGATATGGAAAATCGTCAGTTTGAG
    TTGGTCCAAGAATTAAATGACAATGTGGAACTACCAGTTCAAGTGACCATCGCATCTGGA
    TTTCCCAAGGGAGACAAGCTGGAGTTCATCGCTCAAAAAGTAACCGAACTGGGTGCTAGC
    CAAATCTGGGCCTTTCCTGCAGACTGGTCAGTTGCCAAGTGGGATGGCAAGAAATTGGGT
    AAAAAAGTTGAAAAACTAGAAAAAATTGCCCTTGGAGCAGCCGAGCAAAGCAAGCGTAAT
    ATTGTACCAAGTATTAAACTTTTCGAGAAAAAAGCAGATTTTCTAGCTCAGCTGGACCAG
    TTTGACTCTATCATAGTAGCCTATGAAGAATCAGCTAAAGAAGGAGAAGCCGCTGCGCTT
    CTGCAAGCAGTCACTGGTCTTGAAACAGGAGCCAAACTGCTCTTTATCTTTGGTCCAGAA
    GGCGGTCTCTCACCTGCAGAAATCGAAAGTTTTGAAGCTAAAGGAGCCGTTTTGGCAGGC
    CTAGGTCCTCGTATTTTGCGAGCAGAAACAGCACCGCTTTACGCTTTATCAGCCCTTAGT
    GTTTTAGTAGAATTAGAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    744

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPR_RS07975 [old locus tag: spr1607 ]
  • symbol: SPR_RS07975
  • description: 16S rRNA (uracil(1498)-N(3))-methyltransferase
  • length: 247
  • theoretical pI: 4.63731
  • theoretical MW: 27155.1
  • GRAVY: -0.057085

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.1.193?  ExPASy
    16S rRNA (uracil1498-N3)-methyltransferase S-adenosyl-L-methionine + uracil1498 in 16S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil1498 in 16S rRNA
  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification RNA methyltransferase, RsmE family (TIGR00046; EC 2.1.1.-; HMM-score: 172.1)
    and 1 more
    heme utilization protein HutZ (TIGR04110; HMM-score: 14.4)
  • TheSEED: see spr1607
  • PFAM:
    SPOUT (CL0098) Methyltrans_RNA; RNA methyltransferase domain (PF04452; HMM-score: 180.2)
    and 3 more
    PUA (CL0178) PUA_4; RNA methyltransferase PUA domain (PF20260; HMM-score: 40.2)
    PK_TIM (CL0151) PEP_mutase; Phosphoenolpyruvate phosphomutase (PF13714; HMM-score: 13.3)
    Toprim-like (CL0413) Toprim_4; Toprim domain (PF13662; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001255
    • TAT(Tat/SPI): 0.000137
    • LIPO(Sec/SPII): 0.000187
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDGIKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQIWAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQFDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVLAGLGPRILRAETAPLYALSALSVLVELEK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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