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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0037 [new locus tag: SPT_RS00195 ]
  • pan locus tag?: PNEUPAN000246000
  • symbol: SPT_0037
  • pan gene symbol?: —
  • synonym:
  • product: integrase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0037 [new locus tag: SPT_RS00195 ]
  • symbol: SPT_0037
  • product: integrase
  • replicon: chromosome
  • strand: +
  • coordinates: 22191..23357
  • length: 1167
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAAATAACAGAATACACCAAAAAAGACGGGTCTACAGTCTATCGCTCTAGCGTCTAC
    CTTGGTATCGATACCGTAACAGGTAAGAAAGTCAAGACGACTATATCAGGGCGAACCAAG
    AGAGAACTCAAAGCCAAAGCGCTACAGGCTCAAATCGACTTTGAAAAAGACGGGTCTACA
    GTATATAAAGCAGTTGAGATAAAGACTTACGCCGAACTGGTGGAGAATTGGCTAGAAACG
    TACTGCCATACGGTTAAAAAATCGACCTTAATGGGTACCAAATTCAAAATAGATAAATAT
    CTACTTCCAGCTTTCGGAAATTATAGGCTGGATAAACTGACGCCCCCAATCATTCAAAAG
    CAAGTCAATCAATGGGCAAAAGACTATAATCAACTAGGCAAAGGGTTTCAAGAGTATCCT
    CTCCTTCACTCGCTAAACAAACGCATACTTAAATATGCCGTATCTTTGCAAGCTATCCCC
    TTTAACCCTGCCCGTGATGTTATCGTGCCACGTCGTAAGGAAAAAGAAGGGCAAAAACTG
    AAATATCTGGATGATGATAACTTAAAAAAATTCTTGACTTACCTGGAGCAGCTGCCAAAC
    ACTTACAAAAATTTCTACGATACGGTGCTATATAAGACGCTTTTAGCGACTGGTTTGCGT
    ATTCGTGAGTGTTTAGCCCTCAAATGGTCTGATATTGACCTAAAAAACGGCACACTAGAC
    GTAAATAAAACGTTAAATATTATCAAAGAAATCACTGGCCCTAAGACTAAATCAAGTATT
    AGGGTAATTGACTTGGATAATAAGACGGTGCTCATGCTACGGCTCTATAAAGCAAGACAA
    TCCCAAATAGGGAAAGAAATGGGGTTGACCTATGAGAAAGTATTCTCTAATAGCTTTGAT
    AAGCATATAGACGCTAGAATGCTTAGTTTCAGGTTAGTAAAACATTTGGAACGTGCTGGA
    TGCCCTCGTTTTACGTTCCACGCCTTCCGCCACACTCATGCTAGTATCTTGCTCAATGCT
    GGACTACCTTACAAAGAGATACAAACACGGCTCGGTCATGCAAAACTTTCTATGACCATG
    GATATTTATAGCCACCTATCCAAAGACAATCAGAAAAATGCTACTTCATTTTATGAAAAA
    GCTATTGAAAAATTAAAAAGTTCCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1167

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0037 [new locus tag: SPT_RS00195 ]
  • symbol: SPT_0037
  • description: integrase
  • length: 388
  • theoretical pI: 10.3018
  • theoretical MW: 44848.8
  • GRAVY: -0.504381

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 91.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 77.1)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 48.7)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 48.7)
  • TheSEED  :
    • Phage integrase: site-specific recombinase
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 104.6)
    and 1 more
    l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 59.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9526
    • Cytoplasmic Membrane Score: 0.0028
    • Cell wall & surface Score: 0.0092
    • Extracellular Score: 0.0354
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.015893
    • TAT(Tat/SPI): 0.00139
    • LIPO(Sec/SPII): 0.002817
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO23891 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELKAKALQAQIDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIPFNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATGLRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHASILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: RegR* (repression) regulon
    RegR*(TF)important in Hyaluronate utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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