From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0216 [new locus tag: SPT_RS01095 ]
  • pan locus tag?: PNEUPAN000902000
  • symbol: ruvA
  • pan gene symbol?: ruvA
  • synonym:
  • product: holliday junction DNA helicase RuvA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0216 [new locus tag: SPT_RS01095 ]
  • symbol: ruvA
  • product: holliday junction DNA helicase RuvA
  • replicon: chromosome
  • strand: +
  • coordinates: 193033..193626
  • length: 594
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTACGCATATTTAAAAGGAATCATTACCAAAATTACTGCCAAATACATTGTTCTTGAA
    ACCAATGGTATTGGTTATATCCTGCATGTGGCCAATCCTTATGCCTATTCAGGTCAGGTT
    AATCAGGAGGATCAGATTTATGTGCATCAGGTTGTGCGTGAGGACGCCCATTTGCTTTAT
    GGATTTCGCTCAGAGGATGAGAAAAAGCTCTTTCTTAGTCTGATTTCGGTCTCTGGGATT
    GGTCCTGTATCAGCTCTTGCTATTATCGCTGCTGATGACAATGCTGGCTTGGTTCAAGCC
    ATTGAAACCAAGAACATCACCTACTTGACCAAGTTCCCTAAAATTGGCAAGAAAACAGCC
    CAGCAGATGGTGCTGGACTTGGAAGGCAAGGTAGTAGTTGCAGGAGATGACCTTCCTGCC
    AAGATCGCAGTGCAAGCAAGTGCTGAAAACCAAGAATTGGAAGAAGCTATGGAAGCCATG
    TTGGCTCTGGGCTACAAGGCAACAGAGCTCAAGAAAATCAAGAAATTCTTTGAAGGAACG
    ACAGATACAGCTGAGAACTATATCAAGTCGGCCCTTAAAATGTTGGTCAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    594

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0216 [new locus tag: SPT_RS01095 ]
  • symbol: RuvA
  • description: holliday junction DNA helicase RuvA
  • length: 197
  • theoretical pI: 6.28145
  • theoretical MW: 21664
  • GRAVY: 0.0192893

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.1.-?  ExPASy
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair Holliday junction DNA helicase RuvA (TIGR00084; EC 3.6.4.12; HMM-score: 163.2)
    and 2 more
    Cellular processes Cellular processes DNA transformation comEA protein (TIGR01259; HMM-score: 13.7)
    Cellular processes Cellular processes DNA transformation competence protein ComEA helix-hairpin-helix repeat region (TIGR00426; HMM-score: 13)
  • TheSEED  :
    • Holliday junction DNA helicase RuvA
    DNA Metabolism DNA recombination RuvABC plus a hypothetical  Holliday junction DNA helicase RuvA
    and 1 more
    DNA Metabolism DNA replication DNA-replication  Holliday junction DNA helicase RuvA
  • PFAM:
    OB (CL0021) RuvA_N; RuvA N terminal domain (PF01330; HMM-score: 71)
    and 4 more
    HHH (CL0198) HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 45.1)
    UBA (CL0214) RuvA_C; RuvA, C-terminal domain (PF07499; HMM-score: 24.8)
    HHH (CL0198) HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 15)
    HHH_3; Helix-hairpin-helix motif (PF12836; HMM-score: 14.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9905
    • Cytoplasmic Membrane Score: 0.0082
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0011
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.021166
    • TAT(Tat/SPI): 0.000996
    • LIPO(Sec/SPII): 0.001545
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEDQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: RegR* (repression) regulon
    RegR*(TF)important in Hyaluronate utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPT_0216&oldid=165056"