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SPN034183
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SPN994038
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SPNA45
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ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0325 [new locus tag: SPT_RS01645 ]
  • pan locus tag?: PNEUPAN001018000
  • symbol: SPT_0325
  • pan gene symbol?: rsuA-1
  • synonym:
  • product: ribosomal small subunit pseudouridine synthase A, putative

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0325 [new locus tag: SPT_RS01645 ]
  • symbol: SPT_0325
  • product: ribosomal small subunit pseudouridine synthase A, putative
  • replicon: chromosome
  • strand: +
  • coordinates: 290652..291374
  • length: 723
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAGATTAGATAAATTTTTAGTTGCCTGTGCGGTGGGAAGTCGGACTGAGGTCAAAAAC
    TTGCTCAAGGCTGGGCGCGTGACTGTAAATGGTAAAAAAGAAAAATCAGCTAAATTGCAG
    ATTGATGAAAAAATAGATGAGATTCGCTTTGATGGGCAAGTGTTGGAGTATGAAGAGTTT
    GTCTACTACATGATGAACAAGCCCAAAGGAGTTATCTCAGCGACTGAGGATCCCAAGCAC
    AGAACCGTTCTGGACTTGTTGGATGACTTGGCGCGGAGTAAGGAAGTTTTCCCAGTAGGA
    CGCTTGGATATTGACACGCATGGTCTTTTGCTCTTGACCAATGATGGTCAGCTGGCTCAT
    GTTCTTCTTTCGCCCAAGCGTCATGTGGATAAGACTTATCTGGCACAAGTCAAGGGAATC
    ATGACCCAAGAAGATGTGGAGACATTTGCTGAGGGTATTCCTCTCAAAGACTTTACCTGT
    CAACCCGCTATACTGGAGCTTGTATCCATAGATACAGAAAAGAATCAGAGCCAAATCCGT
    GTGACCATTGCAGAAGGGAAGTTTCATCAGATCAAGCGTATGGTGGGCTACTGTGGCAAG
    GAAGTGGTGGACTTGCAACGATTGACTATGGGAACTTTAGTATTAGATGAGAACCTGGAA
    CGAGGGGAATGGCGTCGCTTGACCAAGGAAGAATTAGAAATTCTCCGCGCTAATATTATT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    723

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0325 [new locus tag: SPT_RS01645 ]
  • symbol: SPT_0325
  • description: ribosomal small subunit pseudouridine synthase A, putative
  • length: 240
  • theoretical pI: 6.37557
  • theoretical MW: 27335.5
  • GRAVY: -0.294583

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 171.9)
    and 3 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 48.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 25.2)
    Unknown function General TlyA family rRNA methyltransferase/putative hemolysin (TIGR00478; HMM-score: 16.4)
  • TheSEED  :
    • Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70)
  • PFAM:
    PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 72.4)
    and 2 more
    S4 (CL0492) S4; S4 domain (PF01479; HMM-score: 34)
    S4_2; S4 domain (PF13275; HMM-score: 15.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9851
    • Cytoplasmic Membrane Score: 0.0127
    • Cell wall & surface Score: 0.002
    • Extracellular Score: 0.0002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.041039
    • TAT(Tat/SPI): 0.009279
    • LIPO(Sec/SPII): 0.013158
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO23962 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEKIDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRLDIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTCQPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDENLERGEWRRLTKEELEILRANII

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: RegR* (repression) regulon
    RegR*(TF)important in Hyaluronate utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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