From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0760 [new locus tag: SPT_RS03785 ]
  • pan locus tag?: PNEUPAN001687000
  • symbol: upp
  • pan gene symbol?: upp
  • synonym:
  • product: uracil phosphoribosyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0760 [new locus tag: SPT_RS03785 ]
  • symbol: upp
  • product: uracil phosphoribosyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 721460..722110
  • length: 651
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    TTGAAAGAAGGAATTCCAAAAATGGGAAAAATTGAAGTTATTAATCACCCACTGATTCAA
    CACAAATTGTCAATCTTGCGTCGTACAGATACTTCTACAAAAGCTTTTCGTGAGCTAGTA
    GATGAGATTGCAATGTTGATGGGGTATGAAGTACTTCGTGATCTTCCACTAGAAGATGTG
    GAAATCGAAACACCAATTACAAAAACAGTTCAAAAACAATTGGCAGGTAAGAAATTGGCC
    ATCGTCCCAATCTTGCGTGCAGGTATCGGGATGGTTGATGGTCTCTTGAGCTTGGTTCCA
    GCTGCTAAAGTTGGCCACATCGGTATGTACCGTGATGAAGAAACACTTCAACCAGTTGAA
    TACTTGGTGAAATTGCCTGAGGACATTGACCAACGTCAAATTTTTGTAGTAGACCCAATG
    TTGGCAACAGGTGGCTCAGCAATCTTGGCTGTTGATTCTCTTAAAAAACGTGGCGCATCA
    AATATCAAATTTGTCTGCCTTGTATCTGCTCCAGAGGGTGTAAAAGCCCTTCAAGAAGCT
    CATCCAGATGTAGAAATCTTTACAGCAGCCTTGGATGAACGTTTGAACGAACACGGTTAT
    ATCGTTCCAGGTCTTGGAGATGCTGGAGACCGCTTGTTCGGTACAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    651

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_0760 [new locus tag: SPT_RS03785 ]
  • symbol: Upp
  • description: uracil phosphoribosyltransferase
  • length: 216
  • theoretical pI: 5.68427
  • theoretical MW: 23655.5
  • GRAVY: 0.0412037

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.2.9?  ExPASy
    Uracil phosphoribosyltransferase UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate
  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uracil phosphoribosyltransferase (TIGR01091; EC 2.4.2.9; HMM-score: 303.5)
    and 6 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis ribose-phosphate diphosphokinase (TIGR01251; EC 2.7.6.1; HMM-score: 26.8)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 26.2)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 15.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 14.6)
    Cellular processes Cellular processes DNA transformation comF family protein (TIGR00201; HMM-score: 12.6)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 12.6)
  • TheSEED  :
    • Uracil phosphoribosyltransferase (EC 2.4.2.9)
    Nucleosides and Nucleotides Pyrimidines De Novo Pyrimidine Synthesis  Uracil phosphoribosyltransferase (EC 2.4.2.9)
    and 1 more
    Nucleosides and Nucleotides Pyrimidines pyrimidine conversions  Uracil phosphoribosyltransferase (EC 2.4.2.9)
  • PFAM:
    PRTase-like (CL0533) UPRTase; Uracil phosphoribosyltransferase (PF14681; HMM-score: 261.9)
    and 1 more
    Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 45.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9656
    • Cytoplasmic Membrane Score: 0.0065
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0276
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002359
    • TAT(Tat/SPI): 0.000255
    • LIPO(Sec/SPII): 0.000242
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO23245 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKEGIPKMGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEVLRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCLVSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPT_0760&oldid=165592"