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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Taiwan19F-14
- locus tag: SPT_1595 [new locus tag: SPT_RS07920 ]
- pan locus tag?: PNEUPAN003071000
- symbol: SPT_1595
- pan gene symbol?: gpmA
- synonym:
- product: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase) (pgam) (bpg-dependent pgam) (dpgm)
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPT_1595 [new locus tag: SPT_RS07920 ]
- symbol: SPT_1595
- product: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase) (pgam) (bpg-dependent pgam) (dpgm)
- replicon: chromosome
- strand: -
- coordinates: 1517596..1518288
- length: 693
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000921 (1517596..1518288) NCBI
- BioCyc: see SPT_RS07920
- MicrobesOnline: 7475313 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1468 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGGTAAAATTGGTTTTTGCTCGCCACGGTGAGTCTGAATGGAACAAAGCTAACCTTTTC
ACTGGTTGGGCTGATGTTGATTTGTCTGAAAAAGGTACACAACAAGCGATTGACGCTGGT
AAATTGATCAAAGAAGCTGGTATCAAATTTGACCAAGCTTACACTTCAGTATTGAAACGT
GCTATCAAAACAACTAACTTGGCTCTTGAAGCTTCTGACCAATTGTGGGTTCCAGTTGAA
AAATCATGGCGCTTGAACGAACGTCACTACGGTGGTTTGACTGGTAAAAATAAAGCTGAA
GCTGCTGAACAATTTGGTGATGAGCAAGTTCACATCTGGCGTCGTTCATACGATGTATTG
CCTCCAAACATGGACCGTGATGATGAGCACTCAGCTCACACAGACCGTCGTTACGCTTCA
CTTGACGACTCAGTTATCCCAGATGCTGAAAACTTGAAAGTGACTTTGGAACGTGCTCTT
CCATTCTGGGAAGATAAAATCGCTCCAGCTCTTAAAGATGGTAAAAACGTATTCGTAGGA
GCTCACGGTAACTCAATCCGTGCCCTTGTAAAACACATCAAAGGTTTGTCAGATGATGAG
ATCATGGACGTGGAAATCCCTAACTTCCCACCATTGGTATTCGAATTCGACGAAAAATTG
AACGTTGTTTCTGAATACTACCTTGGAAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPT_1595 [new locus tag: SPT_RS07920 ]
- symbol: SPT_1595
- description: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase) (pgam) (bpg-dependent pgam) (dpgm)
- length: 230
- theoretical pI: 5.20726
- theoretical MW: 26050.1
- GRAVY: -0.526087
⊟Function[edit | edit source]
- reaction: EC 5.4.2.1? ExPASyTransferred entry: 5.4.2.11 and 5.4.2.12
- TIGRFAM: phosphoglycerate mutase 1 family (TIGR01258; HMM-score: 354.5)and 3 moreBiosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin alpha-ribazole phosphatase (TIGR03162; EC 3.1.3.73; HMM-score: 78.1)probable phosphomutase, MSMEG_4193 family (TIGR03848; EC 5.4.2.-; HMM-score: 41.3)Regulatory functions Protein interactions phosphohistidine phosphatase SixA (TIGR00249; EC 3.1.3.-; HMM-score: 20.4)
- TheSEED :
- Phosphoglycerate mutase (EC 5.4.2.11)
Carbohydrates Central carbohydrate metabolism Entner-Doudoroff Pathway Phosphoglycerate mutase (EC 5.4.2.1)and 3 moreCarbohydrates Central carbohydrate metabolism Entner-Doudoroff Pathway Phosphoglycerate mutase (EC 5.4.2.11) - PFAM: His_phosphatase (CL0071) His_Phos_1; Histidine phosphatase superfamily (branch 1) (PF00300; HMM-score: 127.6)and 1 moreno clan defined Imm70; Immunity protein 70 (PF15601; HMM-score: 12.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9859
- Cytoplasmic Membrane Score: 0.0006
- Cell wall & surface Score: 0.0002
- Extracellular Score: 0.0133
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006577
- TAT(Tat/SPI): 0.000364
- LIPO(Sec/SPII): 0.001768
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1468 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]