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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_RS06895 [old locus tag: SPV_1292 ]
  • pan locus tag?: PNEUPAN002746000
  • symbol: SPV_RS06895
  • pan gene symbol?: ogt
  • synonym:
  • product: methylated-DNA--[protein]-cysteine S-methyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPV_RS06895 [old locus tag: SPV_1292 ]
  • symbol: SPV_RS06895
  • product: methylated-DNA--[protein]-cysteine S-methyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1313504..1314034
  • length: 531
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCAAAAGAAGTATGTAAAAATCCTCTACTCCTCACCAATTGGTATTCTATCACTTGTA
    GCTGATGACCATTATTTGTATGGAATTTGGGTTCAGGAGCAGAAGCATTTTGAGAGGGGA
    CTAGGAGATGAAACGATAGAAGAAGTTGTTAGTCATCCTATTTTAGACCCAGTTATTGCT
    TGCTTAGATGATTACTTTAAAGGCAAGCCTCAGGATTTATCCAACTTGCTCTTGGCGCCA
    ATCGGAACGAATTTTGAAAAGAGAGTTTGGGACTATTTACAGGGCATTCCTTATGGTCAG
    ACAGTGACCTATGGACAAATTGCTCAAGACCTGCAAGTGGCTTCTGCTCAAGCAATTGGT
    GGAGCAGTGGGACGCAATCCTTGGTCTATCCTAGTACCTTGTCATCGTGTGTTGGGAGCA
    GGCAAGCGTCTGACAGGTTATGCTGCAGGAGTGGAAAAGAAAGCTTGGCTCTTGGAGCAT
    GAAGGAGTAGATTTTAAAGATAGAAACAATAGAAGGAGAAGCACATGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    531

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPV_RS06895 [old locus tag: SPV_1292 ]
  • symbol: SPV_RS06895
  • description: methylated-DNA--[protein]-cysteine S-methyltransferase
  • length: 176
  • theoretical pI: 7.54934
  • theoretical MW: 19727.4
  • GRAVY: -0.25

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.1.63?  ExPASy
    Methylated-DNA--[protein]-cysteine S-methyltransferase DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine DNA (containing 4-O-methylthymine) + protein L-cysteine = DNA (without 4-O-methylthymine) + protein S-methyl-L-cysteine
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair methylated-DNA--[protein]-cysteine S-methyltransferase (TIGR00589; EC 2.1.1.63; HMM-score: 98.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    HTH (CL0123) DNA_binding_1; 6-O-methylguanine DNA methyltransferase, DNA binding domain (PF01035; HMM-score: 106.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9923
    • Cytoplasmic Membrane Score: 0.0028
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0047
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.058855
    • TAT(Tat/SPI): 0.000426
    • LIPO(Sec/SPII): 0.039999
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001170347 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDETIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTVTYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEHEGVDFKDRNNRRRSTC

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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