From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_0303 [new locus tag: SP_RS01480 ]
  • pan locus tag?: PNEUPAN001053000
  • symbol: bglA-1
  • pan gene symbol?: celA
  • synonym:
  • product: 6-phospho-beta-glucosidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_0303 [new locus tag: SP_RS01480 ]
  • symbol: bglA-1
  • product: 6-phospho-beta-glucosidase
  • replicon: chromosome
  • strand: +
  • coordinates: 276838..278274
  • length: 1437
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGACTACTTTTAAAGATGGATTTTTATGGGGTGGTGCTGTTGCTGCTCATCAACTTGAA
    GGTGGATGGCAAGAAGGTGGCAAGGGAATTAGTGTTGCTGATGTTATGACTGCTGGTCGT
    CATGGAGTAGCTCGTGAAATTACTTTGGGAGTTTTAGAGGGTAAATATTATCCAAATCAT
    GAGGCGATAGATTTTTATCACCGTTATAAAGAAGATATAGCACTTTTTGCTGAAATGGGA
    TTCAAGTGCTTCCGTACCTCTATTGCATGGACACGTATCTTTCCAAAAGGTGATGAGTTA
    GAGCCGAATGAAGAAGGATTACAGTTTTATGATAATCTTTTTGATGAATGCTTAAAGAAT
    GGTATTGAACCTGTCATCACTCTATCTCATTTTGAAATGCCTTATCACTTAGTGACCGAA
    TATGGTGGTTGGAAAAATAGGAAATTGATTGATTTCTTTGCTCGTTTTGCAGAAGTCGTA
    TTTAAACGTTACAAAGATAAGGTTAAATATTGGATGACTTTCAATGAAATCAATAATCAA
    GCGAATTATCAGGAAGATTTTGCACCATTTACTAACTCAGGTATTGTATATGAGGAAGGT
    GATAATAGAGAAGCAATTATGTATCAAGCAGCACATTACGAATTAGTTGCTTCTGCACGA
    GCTGTAAAAATTGGTCATGAGATTAATCCAGATTTTCAAATAGGTTGTATGATTGCGATG
    TGTCCAATTTATCCAGTTACTTGCAATCCTAAGGATATCTTAATGGCAATGAAAGCTATG
    CAGAAGCGTTATTATTTTGCTGATGTGCATGTTTTAGGTAAATATCCTGAGCATATTTTC
    AAGTATTGGGAACGAAAAGGTATTTCAGTTGATTTTACTGCCCAGGATAAAGAAGATTTA
    CTTGGTGGGACTGTAGATTACATTGGTTTCAGTTACTATATGTCCTTTGCTATCGACTCT
    CATCGTGAAAATAATCCTTATTTTGATTATCTTGAAACAGAAGATTTAGTGAAAAATAAT
    TATGTTAAGGCTTCTGAATGGGAGTGGCAAATTGATCCAGAAGGTTTGCGTTATGCGTTA
    AATTGGTTTACAGACCACTATCACTTACCACTCTTTATTGTTGAAAATGGTTTTGGAGCT
    ATAGATCAAGTTGCAGCAGATGGTATGGTACATGATGATTATAGAATTGAATATCTAGGT
    GCCCATATTCGTGAAATGAAAAAGGCTGTAGTTGAAGATGGTGTTGATTTAATGGGTTAT
    ACTCCATGGGGATGTATTGATTTGGTTTCAGCTGGTACCGGTGAAATGCGGAAACGTTAT
    GGCTTTATTTATGTAGATAAAGATGATAATGGGAAGGGAAGTTATAATCGTTCCCCGAAA
    AAATCTTTTGGCTGGTATAAGGAAGTTATTTCATCTAACGGTGAATCAGTAGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1437

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_0303 [new locus tag: SP_RS01480 ]
  • symbol: BglA-1
  • description: 6-phospho-beta-glucosidase
  • length: 478
  • theoretical pI: 4.90837
  • theoretical MW: 55193.9
  • GRAVY: -0.415272

⊟Function[edit | edit source]

  • reaction:
    EC 3.2.1.86?  ExPASy
    6-phospho-beta-glucosidase 6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate
  • TIGRFAM:
    beta-galactosidase (TIGR03356; HMM-score: 293.2)
    and 1 more
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides 6-phospho-beta-galactosidase (TIGR01233; EC 3.2.1.85; HMM-score: 206.2)
  • TheSEED  :
    • 6-phospho-beta-glucosidase (EC 3.2.1.86)
    Carbohydrates Di- and oligosaccharides Beta-Glucoside Metabolism  6-phospho-beta-glucosidase (EC 3.2.1.86)
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_1; Glycosyl hydrolase family 1 (PF00232; HMM-score: 441.5)
    and 2 more
    Cellulase; Cellulase (glycosyl hydrolase family 5) (PF00150; HMM-score: 24.9)
    no clan defined ArfA; Alternative ribosome-rescue factor A (PF03889; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8927
    • Cytoplasmic Membrane Score: 0.001
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.1062
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.035543
    • TAT(Tat/SPI): 0.008672
    • LIPO(Sec/SPII): 0.010977
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVAREITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEPNEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVVFKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVASARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYPEHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETEDLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHDDYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDNGKGSYNRSPKKSFGWYKEVISSNGESVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CelR* (repression) regulon, CcpA regulon
    CelR*(TF)important in Cellobiose utilization; RegPrecise 
    CcpA(TF)important in Global catabolite repression; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP_0303&oldid=2523"