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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_0327 [new locus tag: SP_RS01590 ]
  • pan locus tag?: PNEUPAN001080000
  • symbol: SP_0327
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_0327 [new locus tag: SP_RS01590 ]
  • symbol: SP_0327
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 299300..300940
  • length: 1641
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGAAAGAAGAAAGAAGACAATTTTTTGAAAGAGTCGATGGAAATCAATGTCGTGATTAT
    ATCTTGTCGCACTGTTCAAAAGACTATGAGAAAGTCAAGAGTTCCCTTGAACGCTTGATG
    GACAATCGTTTTATGTTTGATAGTCCTTGGGATATGGAGCCTTGTTCAAAAATCCATCAA
    ATCCAGCCGATGGTATGGGATCAAGTATTTGAAGATGATCCAGAATGGTCTTATATGCTC
    AATCGACAAGAATATCTCTTGCAGTTTATGATAGGGTATCTGGTAGAAGGAGATAAGGAC
    TATATTCAAAAGTGCAAGTTCTTTCTATTTGATTGGATTGAGCAGGTGAGAGAATTTTCT
    CCTCAATCCTTGATGACTAGAACCTTGGATACGGGTATTCGTTCCTTTACTTGGTTGAAA
    CTACTCTTGCTCCTCTTGAAATTTGACTTGCTAGAGGAGAAAGAACTAGAGAAAATTTTG
    GTCAGTCTAGAAAAGCAGATTGACTTTATGAAAAGCTACTATCGCGCCAAGTACACCCTT
    AGTAACTGGGGGATTTTACAAACAATTCCGATGCTTGCTATCTATCATTTCTTTTCAGAT
    AAGATGGATCTAGAAGAAGCTTACCATTTTGCTTCAGAGGAGTTGAAACAGCAAATTGAG
    ACACAGATTTTAGGAGATGGAAGCCAGTTTGAACAGTCGATTCTCTATCATGTAGAGGTT
    TATAAAGCCTTGCTGGATTTGTGTCTCTTGCTTCCAGACTTGCAAGATAGTTACCAAGAG
    TTGCTGGAAAAGATGGCGACCTATATTCAAATGATGACAGGCTTAGATGGACGGACTTTG
    GCTTTTGGTGATAGCGATTCTACAGAAACGACAGAAATTTTGAGCCTGTCTGCTGTGGTT
    TTGAACCAGGAAGACCTTCTTAACGGTCTGGATGTTAAAGTTGATTTGCTTAGCCTCTTG
    TTCCTGGGGCGAGAAAAGGTCAAGCGACTGCAGGAATTTGAAAAGAGAGCTTGGCAGCCT
    AAGTCCATGATCTTTGAAGACTCTGGACATGTCTGCATTAAGGATGAACATCGTTATCTA
    TTTTTCAAAAATGGTCCGCTAGGAAGTGCCCATAGTCATAGTGACGAGAATAGTTTTTGC
    TTACAGTATCAAGGCCAACCTATTTTCATAGATGCTGGGCGTTATTCTTATCGGGAGATA
    TATGAACGTTATCTCTTAAAGAGTGCTTGGAGTCATTCGACCTGCATTGTAGATGGGAAA
    GCTCCGGAAAGAATCACGGGATCCTGGGAATATGAATACTATCCTCACTCCCTGTTTTGT
    CACCATAAAGAAAGGGAGGGAGTGCATTATATTGAGGGGGCTTATTGGTCAGCAGAACCT
    GATTTGCCTTATCTTCACAGGAGAAAAATCCTCATGTTGGTAGAGGATGTCTGGCTCTTG
    GTAGATGACATCAGGTGTCAAGGTCAACATGAGGTGTTGACTCAGTTTATCCTTGACAAG
    GATGTGACCTATCAAGATGGGAAAATCAATCAGTTGAGACTATGGAGTGAAGTTGATTTT
    GATTTGGAAGATACCATCATTTCTCCTAAATCCCCAATTATTCACCCCAAATCTAAAAAC
    CATCCAGAATCCTTGCCTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1641


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_0327 [new locus tag: SP_RS01590 ]
  • symbol: SP_0327
  • description: hypothetical protein
  • length: 546
  • theoretical pI: 4.78305
  • theoretical MW: 64754.4
  • GRAVY: -0.419231

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Oligohyaluronate lyase (EC 4.2.2.-)
  • PFAM:
    Gal_mutarotase (CL0103) Hepar_II_III; Heparinase II/III-like protein (PF07940; HMM-score: 86.3)
    and 2 more
    Hy-ly_N (CL0372) Hepar_II_III_N; Heparinase II/III N-terminus (PF16889; HMM-score: 68.2)
    Alginate_lyase; Alginate lyase (PF05426; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7976
    • Cytoplasmic Membrane Score: 0.1286
    • Cell wall & surface Score: 0.0172
    • Extracellular Score: 0.0566
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011824
    • TAT(Tat/SPI): 0.002735
    • LIPO(Sec/SPII): 0.004725
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRFMFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYIQKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKILVSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQIETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLDGRTLAFGDSDSTETTEILSLSAVVLNQEDLLNGLDVKVDLLSLLFLGREKVKRLQEFEKRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDAGRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHYIEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGKINQLRLWSEVDFDLEDTIISPKSPIIHPKSKNHPESLP

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, RegR (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 
    RegR(TF)important in Hyaluronate utilization; RegPrecise 

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟'lacZ' fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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