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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1045 [new locus tag: SP_RS05175 ]
- pan locus tag?: PNEUPAN002094000
- symbol: SP_1045
- pan gene symbol?: —
- synonym:
- product: conserved hypothetical protein TIGR00147
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1045 [new locus tag: SP_RS05175 ]
- symbol: SP_1045
- product: conserved hypothetical protein TIGR00147
- replicon: chromosome
- strand: +
- coordinates: 984090..984974
- length: 885
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AE005672 (984090..984974) NCBI
- BioCyc:
- MicrobesOnline: 116519 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0926 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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841ATGAAAAAAGCAATGGTAATTATCAACCCTACTTCTGGTGGCGAGAAGGCTTTGGATTAC
AAAGAAAAGCTGGAGAATAAAGCAAAAGAATACTTTGAATATGTTGAAACCAAAATTACC
GAAAAAGCGCTGGATGCAACACATTTTGCTGAAGAAGCTTCTCGTGAGCAGTATGATGCA
GTGGTTGTGTTTGGTGGAGATGGAACTGTCAATGAAGTCATTTCAGGTATTGATGAGAGA
GACTACATTCCTAAGTTAGGGATTATCCCAGGCGGTACGGGTAACCTCATTACAAAACTT
TTGGAAATCAATCAAGACATCGATGGCGCAATTGACGAACTGGATTTTGATTTAACCAAT
AAGATTGATATCGGTAAAGCAAATGACAACTATTTTGGTTATATCTTTAGTATCGGTTCT
CTGCCTGAGGCGATTCACAATGTTGAAATAGAGGACAAAACAAAATTCGGTATTTTAACC
TATGCTGTAAATACCATGAAGTCTGTCATGACAGATCAGGTCTTTAACATTAAGGTTGAG
ACAGAAAATGGAAATTATGTTGGTGAAGCTAGCCATGTTTTGGTCCTTTTGACAAATTAC
TTCGCTGATAAGAAAATCTTTGAAGAAAACAAGGACGGCTATGCCAACATTTTGATTCTG
AAAGATGCCTCTATATTCTCCAAATTATCCGTCATTCCTGATTTATTAAAAGGGGATGTT
GTCGCAAATGATAATATCGAGTATATCAAAGCGCGTAATATTAAAATCTCTTCAGATAGT
GAATTGGAGTCAGATGTTGACGGAGATAAATCAGATAACCTACCTGTAGAAATCAAAGTC
CTAGCTCAGCGAGTAGAAGTATTTTCAAAACCGAAAGAGGATTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1045 [new locus tag: SP_RS05175 ]
- symbol: SP_1045
- description: conserved hypothetical protein TIGR00147
- length: 294
- theoretical pI: 4.28828
- theoretical MW: 32681.6
- GRAVY: -0.285714
⊟Function[edit | edit source]
- TIGRFAM: Unknown function Enzymes of unknown specificity lipid kinase, YegS/Rv2252/BmrU family (TIGR00147; EC 2.7.1.-; HMM-score: 156.9)and 1 moreUnknown function Enzymes of unknown specificity lipid kinase YegS (TIGR03702; EC 2.7.1.-; HMM-score: 57.6)
- TheSEED :
- Transcription regulator [contains diacylglycerol kinase catalytic domain]
- PFAM: PFK (CL0240) DAGK_cat; Diacylglycerol kinase catalytic domain (PF00781; HMM-score: 104.2)and 2 moreNAD_kinase_C (CL0701) YegS_C; YegS C-terminal NAD kinase beta sandwich-like domain (PF19279; HMM-score: 36.4)PFK (CL0240) NAD_kinase; ATP-NAD kinase N-terminal domain (PF01513; HMM-score: 22.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.823
- Cytoplasmic Membrane Score: 0.1348
- Cell wall & surface Score: 0.0023
- Extracellular Score: 0.0399
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.01313
- TAT(Tat/SPI): 0.000213
- LIPO(Sec/SPII): 0.001176
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKED
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site: 984031 [1]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0926 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)