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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1204 [new locus tag: SP_RS05915 ]
- pan locus tag?: PNEUPAN002468000
- symbol: SP_1204
- pan gene symbol?: tylA
- synonym:
- product: putative hemolysin A
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1204 [new locus tag: SP_RS05915 ]
- symbol: SP_1204
- product: putative hemolysin A
- replicon: chromosome
- strand: -
- coordinates: 1137314..1137910
- length: 597
- essential: yes [1]
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1137314..1137910) NCBI
- BioCyc: see SP_RS05915
- MicrobesOnline: 116670 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1064 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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541TTGCAGGTCTTTGATTTGTCGGTGGATGGCGCGACTACGATTGATATCGGGGCCTCTACT
GGAGGTTTTACCGATGTCATGCTACAGAATAGTGCCAAGTTGGTCTTTGCAGTCGATGTT
GGTACCAATCAGTTGGCTTGGAAATTACGCCAAGACCCACGAGTTGTCAGCATGGAGCAG
TTCAATTTCCGCTATGCTGAAAAGACTGATTTCGAGCAGGAGCCGAGCTTTGCCAGTATT
GATGTGAGTTTCATTTCCCTTAGTCTGATTTTGCCAGCCTTGCACCGTGTCTTGGCTGAT
CAAGGTCAGGTGGTAGCACTTGTCAAACCTCAGTTTGAGGCAGGACGTGAGCAGATTGGG
AAAAATGGAATTATTCGAGATGCTAAGGTTCATCAGAATGTCCTTGAATCTGTAACAGCT
ATGGCAGTAGAGGTAGGTTTTTCAGTCCTTGGCTTGGACTTTTCTCCCATCCAAGGTGGA
CATGGAAATATTGAATTTTTAGCGTATTTGAAAAAAGAAAAGTCAGCAAGCAATCAGATT
CTTGCTGAGATTAAAGAAGCAGTAGAGAGGGCGCATAGTCAATTTAAAAATGAATAA60
120
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540
597
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1204 [new locus tag: SP_RS05915 ]
- symbol: SP_1204
- description: putative hemolysin A
- length: 198
- theoretical pI: 4.87862
- theoretical MW: 21713.5
- GRAVY: -0.0247475
⊟Function[edit | edit source]
- TIGRFAM: Unknown function General TlyA family rRNA methyltransferase/putative hemolysin (TIGR00478; HMM-score: 180.5)and 1 moreProtein synthesis tRNA and rRNA base modification ribosomal RNA large subunit methyltransferase J (TIGR00438; EC 2.1.1.166; HMM-score: 15.7)
- TheSEED :
- RNA binding methyltransferase FtsJ like
- PFAM: NADP_Rossmann (CL0063) FtsJ; FtsJ-like methyltransferase (PF01728; HMM-score: 51.8)and 1 moreMethyltransf_12; Methyltransferase domain (PF08242; HMM-score: 14.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006351
- TAT(Tat/SPI): 0.001507
- LIPO(Sec/SPII): 0.001251
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MQVFDLSVDGATTIDIGASTGGFTDVMLQNSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEVGFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1064 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Tim van Opijnen, Andrew Camilli
A fine scale phenotype-genotype virulence map of a bacterial pathogen.
Genome Res: 2012, 22(12);2541-51
[PubMed:22826510] [WorldCat.org] [DOI] (I p)