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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1838 [new locus tag: SP_RS09115 ]
- pan locus tag?: PNEUPAN003356000
- symbol: SP_1838
- pan gene symbol?: wcaJ
- synonym:
- product: putative glycosyl transferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1838 [new locus tag: SP_RS09115 ]
- symbol: SP_1838
- product: putative glycosyl transferase
- replicon: chromosome
- strand: -
- coordinates: 1747591..1748283
- length: 693
- essential: yes [1] DEG
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1747591..1748283) NCBI
- BioCyc:
- MicrobesOnline: 117270 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1620 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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661ATGCTGAAATGGGAAGACTTGCCTGTGGAAATGAAATCAAGCGAGGTTGAGTCTTACTAC
CAGCTTGTCTCTAAAAGGAAGGGTTCGCTGATTTTCAAGCGTTGCTTGGACTGGGTTTTG
GCCTTGGTCTTACTGGTTCTGACCTCTCCCATCTTTCTCATCTTGAGCATTTGGATCAAG
TTGGATAGCAAAGGGCCAGTGATTTACAAGCAAGAGCGTGTGACCCAGTACAACCGTCGG
TTCAAGATTTGGAAGTTTCGTACCATGGTGACGGATGCGGATAAAAAAGGAAGTCTGGTG
ACTTCTGCTAACGATAGCCGCATTACCAAGGTTGGAAATTTCATCCGACGTGTCCGTTTG
GACGAACTGCCTCAGTTGGTCAATGTCCTTAAAGGTGAGATGTCCTTTGTCGGTACACGA
CCTGAAGTGCCACGTTATACAGAGCAGTATAGCCCTGAAATGATGGCAACCTTGCTCTTG
CAAGCAGGGATTACCTCTCCAGCCAGCATCAACTACAAGGATGAGGACACAATTATCAGT
CAAATGACGGAGAAAGGTCTGTCAGTTGATCAGGCCTATGTGGAGCATGTTCTTCCTGAA
AAGATGCGCTATAACCTCGCCTATCTCCGAGAGTTTAGTTTCTTTGGGGACATCAAAATC
ATGTTTCAAACCGTGTTTGAGGTACTAAAATAA60
120
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1838 [new locus tag: SP_RS09115 ]
- symbol: SP_1838
- description: putative glycosyl transferase
- length: 230
- theoretical pI: 9.68305
- theoretical MW: 26785.2
- GRAVY: -0.113478
⊟Function[edit | edit source]
- TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (TIGR03025; HMM-score: 248.6)undecaprenyl-phosphate glucose phosphotransferase (TIGR03023; EC 2.7.8.-; HMM-score: 204.3)and 2 moresugar transferase, PEP-CTERM system associated (TIGR03013; HMM-score: 174.4)undecaprenyl-phosphate galactose phosphotransferase WbaP (TIGR03022; EC 2.7.8.6; HMM-score: 149.3)
- TheSEED :
- Undecaprenyl-phosphate glycophosphotransferase
- PFAM: no clan defined Bac_transf; Bacterial sugar transferase (PF02397; HMM-score: 207.3)and 1 moreCsgA; Minor curli fiber component A (PF17334; HMM-score: 13.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.01
- Cytoplasmic Membrane Score: 9.99
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helix: 1
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0009
- Cytoplasmic Membrane Score: 0.9953
- Cell wall & surface Score: 0
- Extracellular Score: 0.0037
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002837
- TAT(Tat/SPI): 0.000184
- LIPO(Sec/SPII): 0.00101
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVLLVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTSANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLLQAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDIKIMFQTVFEVLK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site: 1748320 [2]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1620 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
Nucleic Acids Res: 2002, 30(14);3152-62
[PubMed:12136097] [WorldCat.org] [DOI] (I p)Tim van Opijnen, Andrew Camilli
A fine scale phenotype-genotype virulence map of a bacterial pathogen.
Genome Res: 2012, 22(12);2541-51
[PubMed:22826510] [WorldCat.org] [DOI] (I p) - ↑ 2.0 2.1 2.2 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)