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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1869 [new locus tag: SP_RS09270 ]
  • pan locus tag?: PNEUPAN003362000
  • symbol: SP_1869
  • pan gene symbol?: piuB
  • synonym:
  • product: iron-compound ABC transporter, permease protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1869 [new locus tag: SP_RS09270 ]
  • symbol: SP_1869
  • product: iron-compound ABC transporter, permease protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1774497..1775471
  • length: 975
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAGGACGGGGTATGAAACTTTCTCATTATTTAATTGGCTTACTTCTACTCCTAGTC
    TTTCTCTCTATTAGCATTGGGACCAGTGATTTTTCATGGGGAAAGCTATTTGATTTCGAC
    CAGCAGACCTGGCTCCTCTTTCAAGAGTCCCGTCTCCCAAGAACTATCAGTATTCTCCTG
    ACTGCCTCTAGTATGAGTATGGCAGGCCTTCTCATGCAGACTATTACCCAAAATCAGTTT
    GCTGCACCGAGTACAGTTGGAACGACTGAAGCCGCCAAACTGGGAATGGTGCTGAGCCTT
    TTTGTCTTTCCATCGGCTAGTCTGACCCACAAGATGCTCTTCGCTTTTGTTTCATCCATC
    GTATTCACCCTCTTCTTCCTAGCCTTTATGACCATTTTTACTGTAAAGGAAAGGTGGATG
    TTGCCTCTGATTGGGATCATCTATAGCGGGATTATCGGCTCAGTCACAGAAGTTATCGCC
    TATCGTTTCAATCTGGTTCAGAGTATGACTGCCTGGACCCAGGGCTCCTTCTCCATGATT
    CAGACCCATCAGTATGAGTGGCTCTTCTTAGGCCTCATCATCCTGATAACCGTTTGGAAA
    TTATCCCAAACCTTCACCATCATGAATCTAGGGAAAGAAACCAGCGAGAGTTTGGGGATT
    TCCTACTCCCTACTTGAAAAACTGGCCCTCTTTCTGGTGGCGCTAACGACAAGCGTCACC
    ATGATTACCGTGGGTGGCCTACCATTTCTCGGAGTTATCGTTCCCAATCTTGTTCGCAAG
    CGCTATGGAGATAATCTAAGTCAAACCAAACTCATGGTCGCACTGGTTGGTGCCAATCTA
    GTTCTGGCTTGCGATATCCTATCCCGAGTTCTGATTAGGCCCTATGAGTTGTCTGTCAGT
    CTCTTGCTAGGAATCATCGGTAGTCTCGTCTTTATCCTACTTCTCTGGAGAGGGGGACGA
    AAAGATGCAGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    975

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1869 [new locus tag: SP_RS09270 ]
  • symbol: SP_1869
  • description: iron-compound ABC transporter, permease protein
  • length: 324
  • theoretical pI: 10.0388
  • theoretical MW: 35956.7
  • GRAVY: 0.775

⊟Function[edit | edit source]

  • TIGRFAM:
    proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 77.6)
    and 1 more
    Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, permease subunit (TIGR03770; HMM-score: 19)
  • TheSEED  :
    • Iron compound ABC uptake transporter permease protein PiuB
    Iron acquisition and metabolism Iron acquisition and metabolism - no subcategory Heme, hemin uptake and utilization systems in GramPositives  Iron compound ABC uptake transporter permease protein PiuB
  • PFAM:
    Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 231.2)
    and 2 more
    ABC-3; ABC 3 transport family (PF00950; HMM-score: 18.6)
    no clan defined Peptidase_A8; Signal peptidase (SPase) II (PF01252; HMM-score: 8.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.352172
    • TAT(Tat/SPI): 0.001592
    • LIPO(Sec/SPII): 0.08986
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKGRGMKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQESRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSASLTHKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNLVQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYSLLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLVLACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY (activation (repression)) regulon
    CodY(TF)important in Amino acid metabolism; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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