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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 23-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS02155 [old locus tag: SP_0437 ]
  • pan locus tag?: PNEUPAN001282000
  • symbol: gatA
  • pan gene symbol?: gatA
  • synonym:
  • product: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS02155 [old locus tag: SP_0437 ]
  • symbol: gatA
  • product: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA
  • replicon: chromosome
  • strand: -
  • coordinates: 410461..411927
  • length: 1467
  • essential: yes [1]

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (410461..411927) NCBI
  • BioCyc:
  • MicrobesOnline: see SP_0437
  • PneumoBrowse for strain D39V: SPV_0397 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGACTTTTAACAATAAAACTATTGAAGAGTTGCACAATCTCCTTGTCTCTAAGGAAATT
    TCTGCAACAGAATTGACCCAAGCAACACTTGAAAATATCAAGTCTCGTGAGGAAGCCCTC
    AATTCATTTGTCACCATCGCTGAGGAGCAAGCTCTTGTTCAAGCTAAAGCCATTGATGAA
    GCTGGAATTGATGCTGACAATGTCCTTTCAGGAATTCCACTTGCTGTTAAGGATAACATC
    TCTACAGACGGTATTCTCACAACTGCTGCCTCAAAAATGCTCTACAACTATGAGCCAATC
    TTTGATGCGACAGCTGTTGCCAATGCAAAAACCAAGGGCATGATTGTCGTTGGAAAGACC
    AACATGGACGAATTTGCTATGGGTGGTTCAGGTGAAACTTCACACTACGGAGCAACTAAA
    AACGCTTGGAACCACAGCAAGGTTCCTGGTGGGTCATCAAGTGGTTCTGCCGCAGCTGTA
    GCCTCAGGACAAGTTCGCTTGTCACTTGGTTCTGATACTGGTGGTTCCATCCGCCAACCT
    GCTGCCTTCAACGGAATCGTTGGTCTCAAACCAACCTACGGAACAGTTTCACGTTTCGGT
    CTCATTGCCTTTGGTAGCTCATTAGACCAGATTGGACCTTTTGCTCCTACTGTTAAGGAA
    AATGCCCTCTTGCTCAACGCTATTGCCAGCGAAGATGCTAAAGACTCTACTTCTGCTCCT
    GTCCGCATCGCCGACTTTACTTCAAAAATCGGCCAAGACATCAAGGGTATGAAAATCGCT
    TTGCCTAAGGAATACCTAGGCGAAGGAATTGATCCAGAGGTTAAGGAAACAATCTTAAAC
    GCGGCCAAACACTTTGAAAAATTGGGTGCTATCGTCGAAGAAGTCAGCCTTCCTCACTCT
    AAATACGGTGTTGCCGTTTATTACATCATCGCTTCATCAGAAGCTTCATCAAACTTGCAA
    CGCTTCGACGGTATCCGTTACGGCTATCGCGCAGAAGATGCAACCAACCTTGATGAAATC
    TATGTAAACAGCCGAAGCCAAGGTTTTGGTGAAGAGGTAAAACGTCGTATCATGCTGGGT
    ACTTTCAGTCTTTCATCAGGTTACTATGATGCCTACTACAAAAAGGCTGGTCAAGTCCGT
    ACCCTCATCATTCAAGATTTCGAAAAAGTCTTCGCGGATTACGATTTGATTTTGGGTCCA
    ACTGCTCCAAGTGTTGCCTATGACTTGGATTCTCTCAACCATGACCCAGTTGCCATGTAC
    TTAGCCGACCTATTGACCATACCTGTAAACTTGGCAGGACTGCCTGGAATTTCGATTCCT
    GCTGGATTCTCTCAAGGTCTACCTGTCGGACTCCAATTGATTGGTCCCAAGTACTCTGAG
    GAAACCATTTACCAAGCTGCTGCTGCTTTTGAAGCAACAACAGACTACCACAAACAACAA
    CCCGTGATTTTTGGAGGTGACAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1467

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS02155 [old locus tag: SP_0437 ]
  • symbol: GatA
  • description: Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA
  • length: 488
  • theoretical pI: 4.644
  • theoretical MW: 52059.3
  • GRAVY: -0.0860656

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA aminoacylation aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit (TIGR00132; EC 6.3.5.-; HMM-score: 613.2)
    and 2 more
    Unknown function Enzymes of unknown specificity amidohydrolase, AtzE family (TIGR02715; EC 3.-.-.-; HMM-score: 296.8)
    Metabolism Central intermediary metabolism Nitrogen metabolism allophanate hydrolase (TIGR02713; EC 3.5.1.54; HMM-score: 246)
  • TheSEED: see SP_0437
  • PFAM:
    no clan defined Amidase; Amidase (PF01425; HMM-score: 489.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.64
    • Cytoplasmic Membrane Score: 0.3
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8613
    • Cytoplasmic Membrane Score: 0.0142
    • Cell wall & surface Score: 0.0042
    • Extracellular Score: 0.1203
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004526
    • TAT(Tat/SPI): 0.000754
    • LIPO(Sec/SPII): 0.00048
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFVTIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFDATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTVKENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKETILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDATNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFADYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVGLQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Tim van Opijnen, Andrew Camilli
    A fine scale phenotype-genotype virulence map of a bacterial pathogen.
    Genome Res: 2012, 22(12);2541-51
    [PubMed:22826510] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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