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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-APR-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS09610 [old locus tag: SP_1911 ]
  • pan locus tag?: PNEUPAN003500000
  • symbol: SP_RS09610
  • pan gene symbol?: ytpP
  • synonym:
  • product: thioredoxin family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS09610 [old locus tag: SP_1911 ]
  • symbol: SP_RS09610
  • product: thioredoxin family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1824358..1824675
  • length: 318
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_003028 (1824358..1824675) NCBI
  • BioCyc: SP_RS09610 BioCyc
  • MicrobesOnline: see SP_1911
  • PneumoBrowse for strain D39V: SPV_1714 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGATACAGCCAGCAAGTTTAGAAGAATTAGCATCTTTAGTGGAAAAAGCGGGCAAGAAG
    GTCTTCATTTTTGTGGCAGACTGGTGTAGCGATTGTCGTTATATTTATCCTGCCTTACCA
    GAGATTGAGGAGACCAATCCAGAGTTCACCTTTATTCGAATGGACCGAGATCAGTATATG
    GATTTGGCCAAACTCTGGGATGTTTACGGAATTCCTAGCCTTGTTGTTCTAGAAAAGGAC
    AAGGAAATCGGTCGTTTTGTCAATCGCGACCGTAAAAGCAAGCAACAAATCAATGACTTT
    TTAGCAGGACTGAAATAG
    60
    120
    180
    240
    300
    318

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP_RS09610 [old locus tag: SP_1911 ]
  • symbol: SP_RS09610
  • description: thioredoxin family protein
  • length: 105
  • theoretical pI: 4.71898
  • theoretical MW: 12249.1
  • GRAVY: -0.267619

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport thioredoxin (TIGR01068; HMM-score: 51.3)
    and 5 more
    Genetic information processing Protein fate Protein folding and stabilization protein disulfide-isomerase domain (TIGR01126; HMM-score: 28.6)
    protein disulfide isomerase (TIGR01130; HMM-score: 20.2)
    Genetic information processing Protein fate Protein folding and stabilization periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily (TIGR00385; HMM-score: 12.9)
    glutaredoxin-like protein, YruB-family (TIGR02196; HMM-score: 12.6)
    putative alkyl hydroperoxide reductase F subunit (TIGR03143; EC 1.6.4.-; HMM-score: 11.1)
  • TheSEED: see SP_1911
  • PFAM:
    Thioredoxin (CL0172) Thioredoxin; Thioredoxin (PF00085; HMM-score: 50.7)
    and 4 more
    Thioredoxin_9; Thioredoxin (PF14595; HMM-score: 37.5)
    Thioredoxin_8; Thioredoxin-like (PF13905; HMM-score: 23.8)
    Thioredoxin_2; Thioredoxin-like domain (PF13098; HMM-score: 19.7)
    Thioredoxin_7; Thioredoxin-like (PF13899; HMM-score: 14.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02875
    • TAT(Tat/SPI): 0.000492
    • LIPO(Sec/SPII): 0.010617
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MIQPASLEELASLVEKAGKKVFIFVADWCSDCRYIYPALPEIEETNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLAGLK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]