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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A026
  • locus tag: T308_00930 [new locus tag: T308_RS00925 ]
  • pan locus tag?: PNEUPAN000916000
  • symbol: T308_00930
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: T308_00930 [new locus tag: T308_RS00925 ]
  • symbol: T308_00930
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 168485..169081
  • length: 597
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP006844 (168485..169081) NCBI
  • BioCyc: see T308_RS00925
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    TTGCAGAATGACAAGGAAATAAGAGAGATAAAAACATCCCTTAATTGCTTATCAAATGGT
    ATGGAGAATGGACTTGAACCTAGAGCGAAGCTAGAGAAAATGAAAAAAAGCCAGCACAGG
    GCTGACTCCTTTATGAATTATTCCATAAAACTATTATATCACAAAGGAGGCCGAGGCATG
    ACACCAGAGCAAGTAAAAGAAAAACTAGAGGGCGTTAAGTGGATAAACAAGGAGATCAAA
    GGCTTATATTTGGAATTGGAAACCCTGGAAGGTGGCATTATCAAAAAACCAACACTAAGC
    CATAGCAGGGTGCAGACAAGTAGAGAGAATAAGACAGAGAACAATCTTATAAGTGTTCTG
    AAGCTAAAAGAGGACACTTTACAGAGAATTGAGCGACTTACTGAAGAGAGAATGAAAATA
    TCTGAGCTAATCGATAAACTGGCCAATCCGCTTGAGCGTTCTGTTCTAAGACTTTTTTAC
    TTGAATGATCTTGTAGTTTCGGAGGTGGCTGAAGAAATAGATAGATCAAATACTACAGTA
    TACATTATAAGGCAAAAAGCTATAGAACACTTAACAGGTATTGTAAACGGGGATTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    597

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: T308_00930 [new locus tag: T308_RS00925 ]
  • symbol: T308_00930
  • description: hypothetical protein
  • length: 198
  • theoretical pI: 9.29227
  • theoretical MW: 22878.3
  • GRAVY: -0.641414

Function[edit | edit source]

  • TIGRFAM:
    RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 34.3)
    and 11 more
    RNA polymerase sigma-70 factor, TIGR02954 family (TIGR02954; HMM-score: 23.5)
    RNA polymerase sigma-70 factor, sigma-B/F/G subfamily (TIGR02980; HMM-score: 23.3)
    RNA polymerase sigma-70 factor, Bacteroides expansion family 1 (TIGR02985; HMM-score: 22.2)
    RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1 (TIGR02984; HMM-score: 22.1)
    RNA polymerase sigma-70 factor, sigma-E family (TIGR02983; HMM-score: 21.8)
    RNA polymerase sigma factor, FliA/WhiG family (TIGR02479; HMM-score: 18.9)
    RNA polymerase sigma-70 factor, TIGR02952 family (TIGR02952; HMM-score: 18.3)
    RNA polymerase sigma-B factor (TIGR02941; HMM-score: 15.6)
    RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family (TIGR02989; HMM-score: 14.6)
    Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-F factor (TIGR02885; HMM-score: 14.1)
    Genetic information processing Transcription Transcription factors RNA polymerase sigma-F factor (TIGR02885; HMM-score: 14.1)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    HTH (CL0123) DUF1492; Protein of unknown function (DUF1492) (PF07374; HMM-score: 41.1)
    and 8 more
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 22.6)
    Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 21.4)
    UPF0122; Putative helix-turn-helix protein, YlxM / p13 like (PF04297; HMM-score: 18.6)
    Terminase_5; Putative ATPase subunit of terminase (gpP-like) (PF06056; HMM-score: 16.2)
    PKinase (CL0016) CotH; CotH kinase protein (PF08757; HMM-score: 14.6)
    PhoU (CL0297) PhoU_div; Protein of unknown function DUF47 (PF01865; HMM-score: 14.2)
    HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 14)
    no clan defined Het-C; Heterokaryon incompatibility protein Het-C (PF07217; HMM-score: 12.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8548
    • Cytoplasmic Membrane Score: 0.0313
    • Cell wall & surface Score: 0.0063
    • Extracellular Score: 0.1077
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006394
    • TAT(Tat/SPI): 0.001388
    • LIPO(Sec/SPII): 0.00157
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AGZ47015 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MQNDKEIREIKTSLNCLSNGMENGLEPRAKLEKMKKSQHRADSFMNYSIKLLYHKGGRGMTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSRVQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYLNDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]